Page last updated: 2024-10-23

berberine and Endotoxemia

berberine has been researched along with Endotoxemia in 10 studies

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
" In the present study reverse transcription-polymerase chain reaction, immunofluorescence, pyrosequencing, ELISA and Oil Red O staining were performed to assess whether berberine can protect against diet-induced obesity, through modulating the gut microbiota and consequently improving metabolic endotoxemia and gastrointestinal hormone levels."7.85Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels. ( Liu, XZ; Pan, W; Xu, JH; Zou, DJ, 2017)
"The effect of berberine hydrochloride (BBR) on inducible cyclooxygenase-2 (COX-2) in small intestinal mucosa and related mechanisms was investigated in a rat model of acute endotoxemia."7.77Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia. ( Feng, AW; Li, JS; Li, N; Li, QR; Mao, Q; Yu, C, 2011)
" In the present study reverse transcription-polymerase chain reaction, immunofluorescence, pyrosequencing, ELISA and Oil Red O staining were performed to assess whether berberine can protect against diet-induced obesity, through modulating the gut microbiota and consequently improving metabolic endotoxemia and gastrointestinal hormone levels."3.85Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels. ( Liu, XZ; Pan, W; Xu, JH; Zou, DJ, 2017)
"The effect of berberine hydrochloride (BBR) on inducible cyclooxygenase-2 (COX-2) in small intestinal mucosa and related mechanisms was investigated in a rat model of acute endotoxemia."3.77Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia. ( Feng, AW; Li, JS; Li, N; Li, QR; Mao, Q; Yu, C, 2011)
"Berberine is thought to be an immunomodulator, so the present study aimed to investigate the effect of berberine on mortality, lung and intestine injury in endotoxemic mice, and the mechanism of its action."1.33Neutral sulfate berberine modulates cytokine secretion and increases survival in endotoxemic mice. ( Fu, YM; Li, CJ; Li, F; Lu, DX; Qi, RB; Wang, HD; Wang, YP, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's9 (90.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, JH1
Liu, XZ1
Pan, W1
Zou, DJ1
Brown, BI1
He, Y1
Yuan, X1
Zhou, G1
Feng, A1
Choi, YY1
Kim, MH1
Han, JM1
Hong, J1
Lee, TH1
Kim, SH1
Yang, WM1
Lee, DU1
Ko, YS1
Kim, HJ1
Chang, KC1
Gu, L1
Li, N3
Gong, J1
Li, Q1
Zhu, W1
Li, J1
Feng, AW2
Yu, C1
Mao, Q1
Li, QR2
Li, JS2
Li, HM1
Wang, YY1
Wang, HD2
Cao, WJ1
Yu, XH1
Lu, DX2
Qi, RB2
Hu, CF1
Yan, YX1
Gao, W1
Zhou, GR1
Yu, R1
Huang, XL1
Li, F1
Wang, YP1
Fu, YM1
Li, CJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
To Test the Efficacy of Novel Berberine Emulsification by TPGS or Quillaja Extract on the Absorption of Berberine Compared to Berberine Powder in Humans[NCT03438292]32 participants (Actual)Interventional2018-09-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for berberine and Endotoxemia

ArticleYear
Nutritional Management of Metabolic Endotoxemia: A Clinical Review.
    Alternative therapies in health and medicine, 2017, Volume: 23, Issue:4

    Topics: Anti-Infective Agents; Berberine; Diet Therapy; Dysbiosis; Endotoxemia; Fermentation; Glutamine; Hum

2017

Other Studies

9 other studies available for berberine and Endotoxemia

ArticleYear
Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels.
    Molecular medicine reports, 2017, Volume: 15, Issue:5

    Topics: Animals; Berberine; Dietary Fats; Endotoxemia; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Mal

2017
Activation of IGF-1/IGFBP-3 signaling by berberine improves intestinal mucosal barrier of rats with acute endotoxemia.
    Fitoterapia, 2018, Volume: 124

    Topics: Anilides; Animals; Berberine; Endotoxemia; Ileum; Insulin-Like Growth Factor Binding Protein 3; Insu

2018
The anti-inflammatory potential of Cortex Phellodendron in vivo and in vitro: down-regulation of NO and iNOS through suppression of NF-κB and MAPK activation.
    International immunopharmacology, 2014, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Cell Line; Cyclooxygenase 2; Cytokines; Down-Regulatio

2014
13-Ethylberberine reduces HMGB1 release through AMPK activation in LPS-activated RAW264.7 cells and protects endotoxemic mice from organ damage.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 86

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Berberine; Endotoxemia; Enzyme Activation; HMGB1 Prot

2017
Berberine ameliorates intestinal epithelial tight-junction damage and down-regulates myosin light chain kinase pathways in a mouse model of endotoxinemia.
    The Journal of infectious diseases, 2011, Jun-01, Volume: 203, Issue:11

    Topics: Animals; Berberine; Disease Models, Animal; Down-Regulation; Endotoxemia; Immunohistochemistry; Inte

2011
Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia.
    Fitoterapia, 2011, Volume: 82, Issue:7

    Topics: Acute Disease; Anilides; Animals; Anti-Inflammatory Agents; Berberine; Coptis; Cyclooxygenase 2; Cyc

2011
Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms.
    Acta pharmacologica Sinica, 2011, Volume: 32, Issue:11

    Topics: Animals; Apoptosis; Berberine; Chemokine CXCL2; Coptis chinensis; Drugs, Chinese Herbal; Endotoxemia

2011
Berberine ameliorates COX-2 expression in rat small intestinal mucosa partially through PPARγ pathway during acute endotoxemia.
    International immunopharmacology, 2012, Volume: 12, Issue:1

    Topics: Anilides; Animals; Berberine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal;

2012
Neutral sulfate berberine modulates cytokine secretion and increases survival in endotoxemic mice.
    Acta pharmacologica Sinica, 2006, Volume: 27, Issue:9

    Topics: Animals; Berberine; Cytokines; Endotoxemia; Interferon-gamma; Interleukin-10; Interleukin-12; Intest

2006