Page last updated: 2024-10-23

berberine and Edema

berberine has been researched along with Edema in 14 studies

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Berberine-loaded gum nanocomplexes were prepared by the ionic complexation between the negative charges of the gums (tragacanth and acacia gum) using a cross-linker for loading cationic berberine and their anti-inflammatory activity was evaluated against carrageenan-induced paw edema in rats."8.12Evaluation of anti-inflammatory response of berberine-loaded gum nanocomplexes in carrageenan-induced acute paw edema in rats. ( Bakshi, J; Dhingra, D; Grewal, S; Kumari, S; Lathar, P; Mehra, M, 2022)
"Berberine-loaded gum nanocomplexes were prepared by the ionic complexation between the negative charges of the gums (tragacanth and acacia gum) using a cross-linker for loading cationic berberine and their anti-inflammatory activity was evaluated against carrageenan-induced paw edema in rats."4.12Evaluation of anti-inflammatory response of berberine-loaded gum nanocomplexes in carrageenan-induced acute paw edema in rats. ( Bakshi, J; Dhingra, D; Grewal, S; Kumari, S; Lathar, P; Mehra, M, 2022)
" The results showed that DHB effectively mitigated acetic acid-induced vascular permeability, xylene-elicited ear edema and carrageenan-caused paw edema."3.91Dihydroberberine, a hydrogenated derivative of berberine firstly identified in Phellodendri Chinese Cortex, exerts anti-inflammatory effect via dual modulation of NF-κB and MAPK signaling pathways. ( Ai, G; Chen, H; Chen, J; Li, C; Luo, C; Su, Z; Tan, L; Wang, Y; Xie, J; Zeng, H, 2019)
" The aim of this study was to investigate the potential anti-inflammatory properties of coptisine free base (CFB, 8-hydroxy-7,8-dihydrocoptisine) on three animal models, namely xylene-induced ear edema, acetic acid-induced vascular permeability and carrageenan-induced paw edema."3.85Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways. ( Chen, HB; Li, CL; Liang, JL; Lin, GS; Luo, CD; Su, ZR; Tan, LH; Wu, JZ; Xie, JH; Yang, XB; Zeng, HF; Zhang, ZB, 2017)
"The topical anti-inflammatory activities and inhibition of eicosanoid formation of HLJDT and its components were observed in an arachidonic acid (AA)-induced mouse ear edema model."3.78The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase. ( Li, L; Li, Y; Liu, R; Shan, L; Yuan, X; Zeng, H; Zhang, W, 2012)
" 2) Mice with xylene-induced acute exudative edema and acetic acid-induced writhing."3.77Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid. ( Guo, Z; Li, C; Li, Q; Li, Y; Liu, L; Long, Y; Mei, Q; Niu, Y; Sun, Y; Wang, Y; Wu, H; Zhang, M, 2011)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's7 (50.00)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Bakshi, J1
Lathar, P1
Mehra, M1
Grewal, S1
Dhingra, D1
Kumari, S1
Del Gaudio, MP1
Kraus, SI1
Melzer, TM1
Bustos, PS1
Ortega, MG1
Tan, L1
Wang, Y3
Ai, G1
Luo, C1
Chen, H1
Li, C2
Zeng, H2
Xie, J1
Chen, J1
Su, Z1
Dai, X1
Ding, M1
Zhang, W2
Xuan, Z1
Liang, J1
Yang, D1
Zhang, Q1
Su, B1
Zhu, H1
Jia, X1
Li, G1
Wang, T1
Zhang, X1
Zhao, S1
Wu, J3
Peng, S1
Zhao, M1
Chen, HB1
Luo, CD1
Liang, JL1
Zhang, ZB1
Lin, GS1
Wu, JZ1
Li, CL1
Tan, LH1
Yang, XB1
Su, ZR1
Xie, JH1
Zeng, HF1
Luo, Y1
Jiang, Q1
Li, S1
Huang, W1
Xiang, L1
Liu, D1
Hu, Y1
Wang, P2
Lu, X1
Zhang, G1
Wang, F2
Meng, X2
Zhang, H1
Hu, B1
Yang, L1
Zhang, M1
Long, Y1
Sun, Y1
Li, Q1
Wu, H1
Guo, Z1
Li, Y2
Niu, Y1
Liu, L1
Mei, Q1
Li, L1
Shan, L1
Yuan, X1
Liu, R1
Vaidya, AB1
Rajagopalan, TG1
Kale, AG1
Levine, RJ1
Ivanovska, N1
Philipov, S1
Xu, X1
Malavé, A1
Yeşilada, E1
Küpeli, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients[NCT05896878]20 participants (Anticipated)Interventional2023-07-10Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

14 other studies available for berberine and Edema

ArticleYear
Evaluation of anti-inflammatory response of berberine-loaded gum nanocomplexes in carrageenan-induced acute paw edema in rats.
    Pharmacological reports : PR, 2022, Volume: 74, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Carrageenan; Edema; Inflammation; Rats

2022
Antinociceptive effect and identification of berberine alkaloid in Berberis ruscifolia extracts.
    Journal of ethnopharmacology, 2023, Apr-06, Volume: 305

    Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Berberine; Berberis; Edema; Ethanol; Formaldehyde; Mice

2023
Dihydroberberine, a hydrogenated derivative of berberine firstly identified in Phellodendri Chinese Cortex, exerts anti-inflammatory effect via dual modulation of NF-κB and MAPK signaling pathways.
    International immunopharmacology, 2019, Volume: 75

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Berberine; Capillary Permeability; Carrageenan; Cyto

2019
Anti-Inflammatory Effects of Different Elution Fractions of Er-Miao-San on Acute Inflammation Induced by Carrageenan in Rat Paw Tissue.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Oct-23, Volume: 25

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Carrageenan; Dinoprostone; Drugs, Chinese Herbal; Edem

2019
Development of 13-Cys-BBR as an Agent Having Dual Action of Anti-Thrombosis and Anti-Inflammation.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Disease Models, Animal; Edema; Inflamma

2020
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
    European journal of pharmacology, 2017, Sep-15, Volume: 811

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Berberine; Capillary Permeability; Dinoprostone; Dos

2017
Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1.
    Pharmacological research, 2019, Volume: 147

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Caspase 1; Caspase Inhibitors; Coptis; Edema; Gout; In

2019
Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells.
    European journal of pharmacology, 2016, Jun-05, Volume: 780

    Topics: Animals; Berberine; Coptis; Edema; Enzyme Activation; Gene Expression Regulation; Inflammation Media

2016
Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid.
    European journal of pharmacology, 2011, Jan-25, Volume: 651, Issue:1-3

    Topics: Acetic Acid; Aconitine; Alkaloids; Analgesics; Animals; Antidiarrheals; Behavior, Animal; Berberine;

2011
The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase.
    Journal of ethnopharmacology, 2012, Sep-28, Volume: 143, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Ber

2012
Inhibition of human pregnancy plasma diamine oxidase with alkaloids of Argemone mexicana--berberine and sanguinarine.
    Journal of postgraduate medicine, 1980, Volume: 26, Issue:1

    Topics: Alkaloids; Amine Oxidase (Copper-Containing); Benzophenanthridines; Berberine; Berberine Alkaloids;

1980
Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids.
    International journal of immunopharmacology, 1996, Volume: 18, Issue:10

    Topics: Alkaloids; Animals; Anti-Infective Agents; Antibody Formation; Arthritis, Experimental; Berberine; C

1996
Protective effect of berberine on cyclophosphamide-induced haemorrhagic cystitis in rats.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:5

    Topics: Animals; Berberine; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Drug Interactions;

2001
Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats.
    Journal of ethnopharmacology, 2002, Volume: 79, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

2002