berberine has been researched along with Disease Exacerbation in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine may slow the progression of prediabetes to T2DM in ZDF rats by improving GLP-2 secretion, intestinal permeability, and the structure of the gut microbiota." | 8.02 | Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota. ( Jiang, Y; Kong, Y; Liu, H; Ren, H; Shan, C; Wang, J; Wang, S; Wang, Y; Yang, J; Yang, Y; Zheng, M, 2021) |
| "Berberine (BBR) is an isoquinoline quaternary alkaloid extracted from a variety of medicinal plants." | 6.66 | Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression. ( Bruno, G; Calvani, M; Favre, C; Subbiani, A, 2020) |
| "Berberine may slow the progression of prediabetes to T2DM in ZDF rats by improving GLP-2 secretion, intestinal permeability, and the structure of the gut microbiota." | 4.02 | Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota. ( Jiang, Y; Kong, Y; Liu, H; Ren, H; Shan, C; Wang, J; Wang, S; Wang, Y; Yang, J; Yang, Y; Zheng, M, 2021) |
| "Berberine (BBR) is an isoquinoline quaternary alkaloid extracted from a variety of medicinal plants." | 2.66 | Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression. ( Bruno, G; Calvani, M; Favre, C; Subbiani, A, 2020) |
| "Berberine was one of the active components in Chinese herb and exerted tumor suppressive role in cancer progression, but the exact antitumor mechanism is still not clearly clarified." | 1.72 | β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway. ( Nie, Q; Peng, WW; Wang, Y; Zeng, L; Zhang, X; Zhong, L, 2022) |
| "The anti-diabetic nephropathy properties were systematically analyzed in the diabetic db/db mice treated with Met, BBR or with combination of Met and BBR." | 1.62 | Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation. ( Sun, G; Sun, X; Zhang, B; Zhang, C; Zhang, X, 2021) |
| "Berberine (BBR) is an ancient Chinese medicine and has various beneficial effects on metabolic diseases, including NAFLD/NASH." | 1.62 | Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways. ( Chen, W; Gurley, EC; Hylemon, PB; Kakiyama, G; Lai, G; Liu, J; Pandak, WM; Tai, YL; Wang, X; Wang, Y; Yan, J; Zhang, Y; Zhao, D; Zhou, H, 2021) |
| "KRas is frequently mutated in pancreatic cancers." | 1.62 | GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals. ( Abrams, SL; Akula, SM; Candido, S; Cervello, M; Cocco, L; Duda, P; Falzone, L; Gizak, A; Libra, M; Martelli, AM; McCubrey, JA; Meher, AK; Montalto, G; Rakus, D; Ratti, S; Ruvolo, P; Steelman, LS, 2021) |
| " Demonstration of oral bioavailability and anti-tumorigenic efficacy of dietary berberine, as well as further demonstration of signaling pathway modulation and cell-cycle arrest, implicate this relatively safe, natural compound as a potentially important therapeutic and chemopreventive agent for lung cancer." | 1.37 | Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis. ( Chen, DR; Fu, H; James, MA; Liu, Y; You, M, 2011) |
| "The treatment with berberine, curcumin or picroliv were found to (a) elevate the life span of leukemia harboring animals by more than 60 days; (b) decreased the anemic condition which was highly prevalent in FMuLv alone treated group; (c) histopathological evaluations showed that the compounds tested here inhibited the massive leukemic cell infiltrations to sinusoidal spaces in spleen; (d) decrease the expression of Bcl-2, Raf-1, Erk-1 IFNgamma receptor and erythropoietin; (e) induce the expression of p53." | 1.35 | Inhibition of progression of erythroleukemia induced by Friend virus in BALB/c mice by natural products--berberine, curcumin and picroliv. ( Harikumar, KB; Kuttan, G; Kuttan, R, 2008) |
| "Because type 1 diabetes is caused by T cell-mediated destruction of beta cells and severe islet inflammation, we hypothesized that berberine could ameliorate type 1 diabetes through its immune regulation properties." | 1.35 | Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice. ( Cui, G; Ge, B; Gong, Z; Qin, X; Zang, YQ; Zhang, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, B | 1 |
| Zhang, X | 2 |
| Zhang, C | 1 |
| Sun, G | 1 |
| Sun, X | 1 |
| Nie, Q | 1 |
| Peng, WW | 1 |
| Wang, Y | 3 |
| Zhong, L | 1 |
| Zeng, L | 1 |
| Calvani, M | 1 |
| Subbiani, A | 1 |
| Bruno, G | 1 |
| Favre, C | 1 |
| Tai, YL | 1 |
| Zhao, D | 1 |
| Zhang, Y | 2 |
| Yan, J | 1 |
| Kakiyama, G | 1 |
| Wang, X | 2 |
| Gurley, EC | 1 |
| Liu, J | 3 |
| Lai, G | 1 |
| Hylemon, PB | 1 |
| Pandak, WM | 1 |
| Chen, W | 1 |
| Zhou, H | 1 |
| Abrams, SL | 1 |
| Akula, SM | 1 |
| Meher, AK | 1 |
| Steelman, LS | 1 |
| Gizak, A | 1 |
| Duda, P | 1 |
| Rakus, D | 1 |
| Martelli, AM | 1 |
| Ratti, S | 1 |
| Cocco, L | 1 |
| Montalto, G | 1 |
| Cervello, M | 1 |
| Ruvolo, P | 1 |
| Libra, M | 1 |
| Falzone, L | 1 |
| Candido, S | 1 |
| McCubrey, JA | 1 |
| Liu, H | 1 |
| Zheng, M | 1 |
| Yang, Y | 1 |
| Ren, H | 1 |
| Kong, Y | 1 |
| Wang, S | 1 |
| Wang, J | 1 |
| Jiang, Y | 1 |
| Yang, J | 1 |
| Shan, C | 1 |
| Dai, W | 1 |
| Mu, L | 1 |
| Cui, Y | 1 |
| Li, Y | 1 |
| Chen, P | 1 |
| Xie, H | 1 |
| Tang, QL | 1 |
| Lai, ML | 1 |
| Zhong, YF | 1 |
| Wang, AM | 1 |
| Su, JK | 1 |
| Zhang, MQ | 1 |
| Zhu, T | 1 |
| Li, LL | 1 |
| Xiao, GF | 1 |
| Luo, QZ | 1 |
| Liu, QZ | 1 |
| Yao, KT | 1 |
| Xiao, GH | 1 |
| Harikumar, KB | 1 |
| Kuttan, G | 1 |
| Kuttan, R | 1 |
| Cui, G | 1 |
| Qin, X | 1 |
| Gong, Z | 1 |
| Ge, B | 1 |
| Zang, YQ | 1 |
| James, MA | 1 |
| Fu, H | 1 |
| Liu, Y | 1 |
| Chen, DR | 1 |
| You, M | 1 |
1 review available for berberine and Disease Exacerbation
| Article | Year |
|---|---|
Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression.
Topics: Adrenergic beta-Antagonists; Animals; Berberine; Brain Neoplasms; Cell Proliferation; Dietary Supple | 2020 |
11 other studies available for berberine and Disease Exacerbation
| Article | Year |
|---|---|
Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation.
Topics: Animals; Berberine; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Drug Synerg | 2021 |
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Topics: Aged; Animals; Berberine; beta Catenin; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; | 2022 |
Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways.
Topics: Animals; Berberine; Bile Acids and Salts; Diet, Western; Disease Progression; Fatty Acids; Gene Expr | 2021 |
GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals.
Topics: Adenocarcinoma; Adenylate Kinase; Antineoplastic Agents; bcl-X Protein; Berberine; Biphenyl Compound | 2021 |
Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota.
Topics: Animals; Berberine; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dis | 2021 |
Berberine Promotes Apoptosis of Colorectal Cancer via Regulation of the Long Non-Coding RNA (lncRNA) Cancer Susceptibility Candidate 2 (CASC2)/AU-Binding Factor 1 (AUF1)/B-Cell CLL/Lymphoma 2 (Bcl-2) Axis.
Topics: Apoptosis; Berberine; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; | 2019 |
Antinociceptive effect of berberine on visceral hypersensitivity in rats.
Topics: Acetic Acid; Analgesics; Animals; Berberine; Colon; Defecation; Disease Models, Animal; Disease Prog | 2013 |
Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in Lung Cancer.
Topics: Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Coptis | 2015 |
Inhibition of progression of erythroleukemia induced by Friend virus in BALB/c mice by natural products--berberine, curcumin and picroliv.
Topics: Animals; Antineoplastic Agents; Berberine; Biological Products; Cinnamates; Curcumin; Disease Progre | 2008 |
Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice.
Topics: Animals; Berberine; Cell Differentiation; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Anim | 2009 |
Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis.
Topics: Animals; Berberine; Blotting, Western; Cell Cycle; Cell Proliferation; Diet; Disease Progression; Hu | 2011 |