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berberine and Diabetic Cardiomyopathies

berberine has been researched along with Diabetic Cardiomyopathies in 5 studies

Diabetic Cardiomyopathies: Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.

Research Excerpts

ExcerptRelevanceReference
"Objective To explore the effect of berberine on cardiac fibrosis of diabetic rats by observing the expressions of serum transforming growth factor-β1 (TGF-β1), connective tissue growth factor (CTGF) , collagen type 1 (Col1) and collagen type 3 (Col3) in myocardial tissues of diabetic rats after berberine treatment."7.83[Berberine inhibits cardiac fibrosis of diabetic rats]. ( He, J; Liu, G; Lu, K; Shen, Y; Song, W, 2016)
"Objective To explore the effect of berberine on cardiac fibrosis of diabetic rats by observing the expressions of serum transforming growth factor-β1 (TGF-β1), connective tissue growth factor (CTGF) , collagen type 1 (Col1) and collagen type 3 (Col3) in myocardial tissues of diabetic rats after berberine treatment."3.83[Berberine inhibits cardiac fibrosis of diabetic rats]. ( He, J; Liu, G; Lu, K; Shen, Y; Song, W, 2016)
"Berberine (BBR) is a natural compound extracted from a Chinese herb, with a clinically reported anti‑DCM effect; however, its molecular mechanisms have not yet been fully elucidated."1.91Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway. ( Cai, SQ; Chen, DF; Cheng, CF; Fang, HC; Huang, XJ; Li, ZF; Liu, HL; Ren, ZX; Xiong, Y; Yang, L; Ye, SY; Zhao, LJ, 2023)
"Berberine treatment of palmitate-incubated H9c2 cells reduced hypertrophy, increased α-MHC expression and decreased β-MHC expression."1.42Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells. ( Chang, W; Chen, L; Hatch, GM; Meng, Z; Yao, F; Yu, Y; Zhang, M, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Yang, L1
Cheng, CF1
Li, ZF1
Huang, XJ1
Cai, SQ1
Ye, SY1
Zhao, LJ1
Xiong, Y1
Chen, DF1
Liu, HL1
Ren, ZX1
Fang, HC1
Li, G1
Xing, W1
Zhang, M3
Geng, F1
Yang, H1
Zhang, H1
Zhang, X1
Li, J1
Dong, L1
Gao, F1
Chang, W2
Meng, Z1
Yu, Y2
Yao, F2
Hatch, GM2
Chen, L2
Li, K1
Guan, F1
Lu, K1
Shen, Y1
He, J1
Liu, G1
Song, W1

Other Studies

5 other studies available for berberine and Diabetic Cardiomyopathies

ArticleYear
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway.
    International journal of molecular medicine, 2023, Volume: 51, Issue:6

    Topics: Animals; Berberine; Diabetes Mellitus; Diabetic Cardiomyopathies; Inflammasomes; MicroRNAs; Pyroptos

2023
Antifibrotic cardioprotection of berberine via downregulating myocardial IGF-1 receptor-regulated MMP-2/MMP-9 expression in diabetic rats.
    American journal of physiology. Heart and circulatory physiology, 2018, 10-01, Volume: 315, Issue:4

    Topics: Actins; Animals; Berberine; Blood Glucose; Cell Differentiation; Cell Proliferation; Cells, Cultured

2018
Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells.
    European journal of pharmacology, 2015, Dec-15, Volume: 769

    Topics: AMP-Activated Protein Kinases; Animals; Berberine; Cardiomegaly; Cell Line; Diabetes Mellitus, Type

2015
Berberine Pretreatment Confers Cardioprotection Against Ischemia-Reperfusion Injury in a Rat Model of Type 2 Diabetes.
    Journal of cardiovascular pharmacology and therapeutics, 2016, Volume: 21, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Arrhythmias, Cardiac; Berberine; Biomarkers; Blood Glucose;

2016
[Berberine inhibits cardiac fibrosis of diabetic rats].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2016, Volume: 32, Issue:10

    Topics: Animals; Berberine; Collagen Type III; Connective Tissue Growth Factor; Diabetes Mellitus, Experimen

2016