berberine has been researched along with Diabetes Mellitus, Type 1 in 8 studies
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Latent autoimmune diabetes in adults (LADA) is a heterogeneous form of diabetes, characterized by autoimmune destruction of pancreatic β-cells as well as insulin resistance and is triggered by environmental factors in the context of genetic susceptibility." | 7.11 | Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial. ( Mei, Z; Wu, X; Xiao, Y; Yan, J; Yang, W; Zhang, R; Zhou, Z, 2022) |
| "In animal models, treatment of type 2 diabetes mellitus rats with BBR lowered fasting blood glucose and fasting serum insulin, increased insulin sensitivity, and elevated InsR mRNA as well as PKC activity in the liver." | 5.35 | Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. ( Jiang, JD; Kong, WJ; Li, ZR; Pan, HN; Shan, N; Si, SY; Song, DQ; Wang, YM; Wei, J; Xue, R; Yang, P; You, XF; Zhang, H; Zhao, LX; Zhao, W; Zhou, ZX, 2009) |
| "Latent autoimmune diabetes in adults (LADA) is a heterogeneous form of diabetes, characterized by autoimmune destruction of pancreatic β-cells as well as insulin resistance and is triggered by environmental factors in the context of genetic susceptibility." | 3.11 | Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial. ( Mei, Z; Wu, X; Xiao, Y; Yan, J; Yang, W; Zhang, R; Zhou, Z, 2022) |
| "Berberine (BBR) can ameliorate type 2 diabetes and insulin resistance in many ways." | 1.91 | Berberine Regulates GPX4 to Inhibit Ferroptosis of Islet β Cells. ( Bao, L; Han, J; Jin, Y; Qian, L; Wang, W; Wu, W, 2023) |
| "Berberine is a compound for which both antidiabetic and antiosteoporotic effects have been documented." | 1.72 | Lack of berberine effect on bone mechanical properties in rats with experimentally induced diabetes. ( Cegieła, U; Folwarczna, J; Gajdoš, M; Janas, A; Kisiel-Nawrot, E; Kocik, S; Krivošíková, Z; Londzin, P; Skoczyńska, A; Štefíková, K, 2022) |
| "In animal models, treatment of type 2 diabetes mellitus rats with BBR lowered fasting blood glucose and fasting serum insulin, increased insulin sensitivity, and elevated InsR mRNA as well as PKC activity in the liver." | 1.35 | Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. ( Jiang, JD; Kong, WJ; Li, ZR; Pan, HN; Shan, N; Si, SY; Song, DQ; Wang, YM; Wei, J; Xue, R; Yang, P; You, XF; Zhang, H; Zhao, LX; Zhao, W; Zhou, ZX, 2009) |
| "Because type 1 diabetes is caused by T cell-mediated destruction of beta cells and severe islet inflammation, we hypothesized that berberine could ameliorate type 1 diabetes through its immune regulation properties." | 1.35 | Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice. ( Cui, G; Ge, B; Gong, Z; Qin, X; Zang, YQ; Zhang, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Londzin, P | 1 |
| Kocik, S | 1 |
| Kisiel-Nawrot, E | 1 |
| Janas, A | 1 |
| Skoczyńska, A | 1 |
| Krivošíková, Z | 1 |
| Štefíková, K | 1 |
| Gajdoš, M | 1 |
| Cegieła, U | 1 |
| Folwarczna, J | 1 |
| Zhang, R | 1 |
| Xiao, Y | 1 |
| Yan, J | 1 |
| Yang, W | 1 |
| Wu, X | 1 |
| Mei, Z | 1 |
| Zhou, Z | 1 |
| Bao, L | 1 |
| Jin, Y | 1 |
| Han, J | 1 |
| Wang, W | 1 |
| Qian, L | 1 |
| Wu, W | 1 |
| Sun, J | 1 |
| Bao, H | 1 |
| Peng, Y | 1 |
| Zhang, H | 3 |
| Sun, Y | 1 |
| Qi, J | 1 |
| Gao, Y | 1 |
| Kong, WJ | 1 |
| Song, DQ | 1 |
| Xue, R | 1 |
| Zhao, W | 1 |
| Wei, J | 1 |
| Wang, YM | 1 |
| Shan, N | 1 |
| Zhou, ZX | 1 |
| Yang, P | 1 |
| You, XF | 1 |
| Li, ZR | 1 |
| Si, SY | 1 |
| Zhao, LX | 1 |
| Pan, HN | 1 |
| Jiang, JD | 1 |
| Cui, G | 1 |
| Qin, X | 1 |
| Zhang, Y | 1 |
| Gong, Z | 1 |
| Ge, B | 1 |
| Zang, YQ | 1 |
| Chueh, WH | 2 |
| Lin, JY | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: A Randomized Controlled Trial[NCT04698330] | Phase 4 | 240 participants (Anticipated) | Interventional | 2022-05-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for berberine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial.
Topics: Adult; Berberine; Diabetes Mellitus, Type 1; Glucose Intolerance; Humans; Insulin; Inulin; Latent Au | 2022 |
7 other studies available for berberine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Lack of berberine effect on bone mechanical properties in rats with experimentally induced diabetes.
Topics: Animals; Berberine; Bone Density; Bone Remodeling; Diabetes Mellitus, Experimental; Diabetes Mellitu | 2022 |
Berberine Regulates GPX4 to Inhibit Ferroptosis of Islet β Cells.
Topics: Berberine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ferroptosis; Reactive Oxygen Specie | 2023 |
Improvement of intestinal transport, absorption and anti-diabetic efficacy of berberine by using Gelucire44/14: In vitro, in situ and in vivo studies.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; B | 2018 |
Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression.
Topics: Animals; Berberine; Cell Line, Tumor; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; | 2009 |
Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice.
Topics: Animals; Berberine; Cell Differentiation; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Anim | 2009 |
Berberine, an isoquinoline alkaloid in herbal plants, protects pancreatic islets and serum lipids in nonobese diabetic mice.
Topics: Animals; Berberine; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 1; Disease Models, A | 2011 |
Protective effect of berberine on serum glucose levels in non-obese diabetic mice.
Topics: Animals; Berberine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Energy Intake; Female; Gl | 2012 |