berberine has been researched along with Colorectal Cancer in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 14 (36.84) | 24.3611 |
| 2020's | 22 (57.89) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Z; Du, S; Fang, S; Guo, S; Su, X; Wei, W; Yang, Y | 1 |
| Al-Bagawi, AH; Fareid, MA; Habotta, OA; Moneim, AEA; Obeidat, ST; Othman, MS | 1 |
| Chang, J; Geng, Z; Hao, X; Liu, J; Tan, X; Wang, Z; Yan, S | 1 |
| Ai, M; Kong, L; Li, J; Ni, L; Sun, P; Xu, R | 1 |
| Fu, WM; Li, SY; Shi, CJ; Zhang, JF | 1 |
| Katiyar, P; Mishra, R; Nathani, S; Roy, P; Sircar, D | 1 |
| Chai, X; Chen, L; Gong, X; Gui, Z; Li, J; Li, M; Li, X; Lu, F; Ma, H; Ma, Z; Tang, X; Ye, X | 1 |
| Chen, T; Li, X; Li, Z; Ma, J; Tian, Y; Wang, Y; Wen, Y; Xu, Q; Yan, J | 1 |
| Chen, H; Guo, Y; Wang, X; Wu, C; Xu, C; Xu, L; Yao, Q; Ye, C; Zhang, J | 1 |
| Iloki Assanga, SB; Lewis Luján, LM; McCarty, MF | 1 |
| Chen, H; Chen, Y; Cui, Y; Fang, J; Gao, Q; Kang, Z; Li, X; Liu, Q; Qian, Y; Wang, Z; Zhao, L; Zhou, C; Zou, T | 1 |
| Abdelfattah-Hassan, A; Ali Alasmary, F; Ali, M; Alqahtani, LS; Bazeed, SM; Elgamal, A; Hussein, EM; Ibrahim, D; Khater, SI; Mahfouz, H; Metwally, AS; Salem, GA; Sheraiba, NI | 1 |
| Abuduaini, N; Cui, J; Feng, B; He, X; Huang, J; Huang, Y; Lu, W; Ma, H; Tang, L; Wang, W; Wang, Y; Zhang, Y | 1 |
| Chen, S; Gao, Q; Huang, S; Ou, Y; Tan, S; Yang, Y | 1 |
| Benante, K; Bergan, R; Cao, Y; Hu, S; Jia, Y; Jovanovic, B; Khan, SA; Li, ZS; Liu, J; Ma, Y; Pan, Y; Richmond, E; Rodriguez, LM; Song, Y; Tull, MB; Umar, A; Wen, A; Wu, K; Xu, L; Xue, X; Yang, GY; Zhang, Y | 1 |
| Gong, C; Hu, X; Li, Z; Lu, D; Wang, C; Xu, Y; Yang, J; Zhu, J; Zong, L | 1 |
| Cao, HL; Cao, XC; Chen, HM; Chen, YX; Dou, XT; Fang, JY; Gao, QY; Kang, Q; Li, N; Liu, SD; Liu, ZJ; Ren, JL; Sheng, JQ; Song, YY; Sun, XM; Wang, BM; Xiao, B; Xu, HZ; Yang, XN; Zhu, W; Zou, TH; Zou, XP | 1 |
| Chan, AT; Kwon, S | 1 |
| Guan, X; Vong, CT; Wang, Y; Xiao, J; Zhao, J; Zheng, X; Zhong, Z | 1 |
| Asemi, Z; Hallajzadeh, J; Maleki Dana, P; Mansournia, MA; Mobini, M; Sharifi, M; Yousefi, B | 1 |
| Huang, L; Li, X; Liu, X; Ma, W; Xiao, Y; Xu, M; Ye, X; Yu, M; Zhang, Y | 1 |
| Huang, TM; Shen, ZQ; Tan, WF; Wang, J | 1 |
| Han, B; Huang, T; Jiang, P; Li, X; Li, Z; Ye, X; Yu, Y | 1 |
| Guan, L; Lai, M; Li, J; Wang, H; Wen, X | 1 |
| Li, TM; Liu, B; Wang, GX; Wu, YY; Zang, LQ | 1 |
| Chen, P; Cui, Y; Dai, W; Li, Y; Mu, L; Wang, X; Xie, H | 2 |
| Dian, LL; Gao, XY; Liang, ZS; Phyo, AT; Qasim, M; Sun, YF; Sun, ZX; Wang, P; Yang, SQ | 1 |
| Cai, Y; Huang, P; Jiang, W; Luo, R; Shi, Y; Sun, Y; Xia, Q | 1 |
| Colburn, NH; Hou, W; Hua, B; Jia, L; Li, W; Lin, H; Matter, MS; Saud, SM; Young, MR | 1 |
| Cai, J; Fan, Z; Ji, Q; Li, Q; Liu, X; Sui, H; Ye, N; Zhou, L; Zhu, H | 1 |
| Cheng, YW; Huang, CC; Jiang, HY; Lai, IL; Lee, JW; Lee, KH; Lee, YC; Sia, P; Su, YH; Tang, WC; Wu, MH | 1 |
| An, HF; Chen, HM; Chen, HY; Fang, JY; Hong, J; Li, M; Ma, X; Qin, WX; Shen, N; Sun, TT; Weng, YR; Yu, J; Yu, TC; Yu, YN; Zhao, HJ | 1 |
| Cao, H; Lu, L; Lu, N; Tong, Z; Zhang, M | 1 |
| Han, B; He, K; Huang, T; Li, L; Li, X; Ma, H; Tian, C; Wang, M; Wang, Y; Xiao, Y; Ye, X; Yi, L | 1 |
| Chen, LX; Li, HR; Li, Y; Liu, SW; Ma, WB; Pan, TC; Wang, LW; Ye, WC; Zhu, LY | 1 |
| Baek, SJ; Piyanuch, R; Sukhthankar, M; Wandee, G | 1 |
| Chung, IK; Kang, MR | 1 |
5 review(s) available for berberine and Colorectal Cancer
| Article | Year |
|---|---|
Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis.
Topics: Adenoma; Berberine; Colorectal Neoplasms; Coptis chinensis; Humans | 2022 |
Berberine and health outcomes: An umbrella review.
Topics: Berberine; Colorectal Neoplasms; Constipation; Humans; Lipids | 2023 |
Targeting beta-catenin signaling for prevention of colorectal cancer - Nutraceutical, drug, and dietary options.
Topics: Anthocyanins; Berberine; beta Catenin; Colorectal Neoplasms; Cyclooxygenase 2; Diet; Dietary Supplements; ErbB Receptors; Humans; Insulin; Insulin-Like Growth Factor I; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Toll-Like Receptor 4 | 2023 |
Preventive effects of chemical drugs on recurrence of colorectal adenomas: systematic review and Bayesian network meta-analysis.
Topics: Adenoma; Berberine; Colorectal Neoplasms; Humans; Network Meta-Analysis; Randomized Controlled Trials as Topic; Sulindac | 2024 |
Targeting of oncogenic signaling pathways by berberine for treatment of colorectal cancer.
Topics: Animals; Berberine; Colorectal Neoplasms; Humans; Signal Transduction | 2020 |
2 trial(s) available for berberine and Colorectal Cancer
| Article | Year |
|---|---|
A Phase I Trial of Berberine in Chinese with Ulcerative Colitis.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Biopsy; China; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Intestinal Mucosa; Male; Mesalamine; Middle Aged; Prospective Studies; Rectum; Severity of Illness Index; Tissue Distribution; Young Adult | 2020 |
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.
Topics: Adenoma; Adolescent; Adult; Aftercare; Aged; Antineoplastic Agents, Phytogenic; Berberine; Chemoprevention; China; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Humans; Intention to Treat Analysis; Middle Aged; Placebos; Plants, Medicinal; Recurrence; Safety; Young Adult | 2020 |
31 other study(ies) available for berberine and Colorectal Cancer
| Article | Year |
|---|---|
Antitumor Activity of Zinc Nanoparticles Synthesized with Berberine on Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cells through Acting on Cox-2/NF-kB and p53 Pathways.
Topics: Adenocarcinoma; Animals; Apoptosis; bcl-2-Associated X Protein; Berberine; Caco-2 Cells; Caspase 3; Chlorocebus aethiops; Colorectal Neoplasms; Fluorouracil; Humans; Metal Nanoparticles; NF-kappa B; Tumor Suppressor Protein p53; Vero Cells; Zinc | 2022 |
Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.
Topics: Animals; Azoxymethane; Berberine; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-kappa B; Occludin; Tandem Mass Spectrometry; Toll-Like Receptor 4 | 2022 |
Berberine inhibited the formation of metastasis by intervening the secondary homing of colorectal cancer cells in the blood circulation to the lung and liver through HEY2.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Berberine; beta Catenin; Cadherins; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Cyclin D1; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Liver Neoplasms; Lung; Mice; Repressor Proteins | 2022 |
Berberine inhibits tumour growth in vivo and in vitro through suppressing the lincROR-Wnt/β-catenin regulatory axis in colorectal cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Humans; Mice; Wnt Signaling Pathway | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms; Colorectal Neoplasms; Humans; Receptors, G-Protein-Coupled; Zinc | 2023 |
Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells.
Topics: Animals; Berberine; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Mice; RNA, Messenger; S Phase; Ubiquitination | 2023 |
Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.
Topics: Animals; Berberine; Carcinogenesis; Colorectal Neoplasms; Diet, High-Fat; Gastrointestinal Microbiome; Lysophosphatidylcholines; Mice; Mice, Inbred C57BL | 2023 |
Berberine might block colorectal carcinogenesis by inhibiting the regulation of B-cell function by Veillonella parvula.
Topics: Animals; Berberine; Carcinogenesis; Colorectal Neoplasms; Humans; Tumor Microenvironment; Veillonella | 2023 |
Prospects of new targeted nanotherapy combining liponiosomes with berberine to combat colorectal cancer development: An in vivo experimental model.
Topics: Animals; Apoptosis; Berberine; Colorectal Neoplasms; Cyclooxygenase 2; Mammals; Models, Theoretical; NF-kappa B; Rats; Vascular Endothelial Growth Factor A | 2023 |
Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancer.
Topics: Animals; Berberine; Cell Line; Colorectal Neoplasms; Humans; IMP Dehydrogenase; Mice; Protein Isoforms | 2023 |
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Topics: Apoptosis; Berberine; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Tumor Cells, Cultured | 2020 |
Extracting the benefits of berberine for colorectal cancer.
Topics: Adenoma; Antineoplastic Agents, Phytogenic; Aspirin; Berberine; Cardiovascular Diseases; Case-Control Studies; Cell Proliferation; China; Colonic Neoplasms; Colonoscopy; Colorectal Neoplasms; Humans; Placebos; Plants, Medicinal; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence | 2020 |
Combined effects of berberine and evodiamine on colorectal cancer cells and cardiomyocytes in vitro.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Berberine; Caco-2 Cells; Cardiotoxicity; Colon; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Chinese Herbal; Epithelial Cells; HT29 Cells; Humans; Intestinal Mucosa; Myocytes, Cardiac; Quinazolines; Rats | 2020 |
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Topics: Animals; Apoptosis; Berberine; Biomarkers, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Resting Phase, Cell Cycle; RNA-Binding Proteins; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Berberine inhibits colorectal tumor growth by suppressing SHH secretion.
Topics: Animals; Antineoplastic Agents; Berberine; Cell Line, Tumor; Colorectal Neoplasms; Hedgehog Proteins; Humans; Mice, Inbred BALB C; Mice, Nude; RNA; RNA Stability; Signal Transduction; Xenograft Model Antitumor Assays | 2021 |
Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
Topics: Animals; Apoptosis; Berberine; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cytochromes c; HCT116 Cells; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2018 |
The Effects of Berberine on the Gut Microbiota in Apc
Topics: Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents; Bacteria; Berberine; beta Catenin; Colorectal Neoplasms; Cyclin D1; Diet, High-Fat; DNA, Bacterial; DNA, Ribosomal; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Male; Mice; Neoplasms, Experimental; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Xenograft Model Antitumor Assays | 2018 |
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; HCT116 Cells; Humans; Intestinal Mucosa; Lactic Acid; Mice; Mice, Nude; Occludin; Permeability; Polyamines; Xenograft Model Antitumor Assays; Zonula Occludens-1 Protein | 2018 |
Berberine Promotes Apoptosis of Colorectal Cancer via Regulation of the Long Non-Coding RNA (lncRNA) Cancer Susceptibility Candidate 2 (CASC2)/AU-Binding Factor 1 (AUF1)/B-Cell CLL/Lymphoma 2 (Bcl-2) Axis.
Topics: Apoptosis; Berberine; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; HT29 Cells; Humans; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; RNA, Long Noncoding; RNA, Messenger; Tumor Suppressor Proteins; Up-Regulation | 2019 |
Long non‑coding RNA CASC2 enhances berberine‑induced cytotoxicity in colorectal cancer cells by silencing BCL2.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Male; Middle Aged; Proto-Oncogene Proteins c-bcl-2; RNA, Long Noncoding; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Proteins | 2019 |
Jatrorrhizine inhibits colorectal carcinoma proliferation and metastasis through Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; beta Catenin; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Structure-Activity Relationship; Wnt Signaling Pathway; Wound Healing | 2019 |
Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Berberine; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Proliferation; Colorectal Neoplasms; Cyclin B; Cyclin B1; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Fluorouracil; G2 Phase Cell Cycle Checkpoints; HT29 Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Mice, Nude; Time Factors; Xenograft Model Antitumor Assays | 2014 |
Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Azoxymethane; Berberine; Carcinogenesis; Caspase 3; Cell Line, Tumor; Colon; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; eIF-2 Kinase; Female; HCT116 Cells; Humans; Mice; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2015 |
Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cell Movement; Colon; Colorectal Neoplasms; Coptis; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 2; Male; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Rectum; Signal Transduction; STAT3 Transcription Factor | 2015 |
Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Berberine; Cell Line, Tumor; Colorectal Neoplasms; Cyclin-Dependent Kinase 4; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; MicroRNAs; Neoplasm Proteins; Resorcinols; RNA, Neoplasm; Signal Transduction | 2015 |
Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment.
Topics: Adenoma; Animals; Berberine; Blotting, Western; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytokines; Feces; Fusobacterium Infections; Fusobacterium nucleatum; Humans; Male; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Microenvironment | 2015 |
[Effect and mechanism of EGFR expression in macrophages on the anti-cancer effect of berberine on colorectal cancer].
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Caspase 3; Colorectal Neoplasms; Genes, erbB-1; Immunohistochemistry; Macrophages; Mice | 2015 |
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Araceae; Berberine; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; HCT116 Cells; Heterografts; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Treatment Outcome | 2017 |
[Berberine activates volume-sensitive chloride channel in human colorectal carcinoma cells].
Topics: Berberine; Cell Line, Tumor; Chloride Channels; Colorectal Neoplasms; Humans; Nitrobenzoates; Osmotic Pressure; Patch-Clamp Techniques; Tamoxifen | 2011 |
Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells.
Topics: Activating Transcription Factor 3; Alkaloids; Apoptosis; Berberine; Biological Products; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Growth Differentiation Factor 15; HCT116 Cells; Humans; Isoquinolines; Luciferases; Protein Kinase Inhibitors; Recombinant Fusion Proteins; RNA, Small Interfering; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2007 |
Down-regulation of DNA topoisomerase IIalpha in human colorectal carcinoma cells resistant to a protoberberine alkaloid, berberrubine.
Topics: Alkaloids; Antigens, Neoplasm; Antineoplastic Agents; Berberine; Colorectal Neoplasms; DNA Topoisomerases, Type II; DNA-Binding Proteins; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Half-Life; Humans; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 2002 |