berberine has been researched along with Colonic Neoplasms in 33 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine was used to determine loss of viable cells and inhibition of arylamine Nacetyltransferase (NAT) activity in a human colon tumor (adenocarcinoma) cell line." | 3.70 | Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells. ( Chang, HL; Chen, GW; Chung, JG; Lin, JG; Wang, TF; Wu, LT, 1999) |
| "Berberine is a plant-derived natural compound that has shown anti-colon cancer potential." | 1.91 | Berberine Reverses the Tumorigenic Function of Colon Cancer Cell-Derived Exosomes. ( Qi, T; Shan, R; Sun, Q; Yang, P, 2023) |
| "Berberine was one of the active components in Chinese herb and exerted tumor suppressive role in cancer progression, but the exact antitumor mechanism is still not clearly clarified." | 1.72 | β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway. ( Nie, Q; Peng, WW; Wang, Y; Zeng, L; Zhang, X; Zhong, L, 2022) |
| "It was found to have anticolon cancer effects." | 1.62 | Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells. ( Li, G; Liang, W; Shen, Y; Tian, X; Zhang, C; Zhang, Y, 2021) |
| "Berberine binding promotes RXRα interaction with nuclear β-catenin, leading to c-Cbl mediated degradation of β-catenin, and consequently inhibits the proliferation of colon cancer cells." | 1.46 | Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells. ( Cao, H; Chen, B; Chen, X; Hou, J; Hu, T; Li, H; Mi, P; Ruan, H; Su, Y; Tian, Y; Wang, H; Wang, X; Wu, D; Xu, B; Zhan, YY; Zhang, L; Zhang, S; Zhang, W; Zhang, XK; Zhang, Y; Zhao, Y, 2017) |
| "Berberine acted to inhibit proliferation through inducing G1/S and G2/M cell cycle arrest, which correlated with regulation of the checkpoint protein expression." | 1.39 | Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells. ( Cao, H; Hu, T; Israel, DA; Liu, L; Lu, N; Peek, RM; Polk, DB; Wang, B; Wang, L; Yan, F, 2013) |
| "Colon cancer is one of the most common malignancies, mainly initiated by the abnormal activation of Wnt/β-catenin signaling." | 1.38 | Berberine inhibits the proliferation of colon cancer cells by inactivating Wnt/β-catenin signaling. ( He, B; Liu, Y; Mu, Y; Wu, K; Yang, Q; Zhou, L; Zhou, Q, 2012) |
| "Berberine inhibited proliferation of colon cancer cells in a dose- and time-dependent manner." | 1.38 | The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells. ( Chidambara Murthy, KN; Jayaprakasha, GK; Patil, BS, 2012) |
| "Berberine is a benzylisoquinoline alkaloid extracted from many kinds of medicinal plants that has been extensively used as a Chinese traditional medicine." | 1.38 | Berberine inhibits human colon cancer cell migration via AMP-activated protein kinase-mediated downregulation of integrin β1 signaling. ( Ha, J; Kim, EJ; Ko, YG; Lee, M; Lee, YJ; Park, JJ; Seo, SM, 2012) |
| "To investigate the anti-colon cancer effects of berberine and possible relationship with cyclooxygenase-2." | 1.36 | [Preventive effects of berberine on experimental colon cancer and relationship with cyclooxygenase-2 expression]. ( Wu, K; Yang, J; Zhou, Q, 2010) |
| "Berberine was found to inhibit cyclooxygenase 2 activity without inhibition of cyclooxygenase 1 activity, and baicalein inhibited cyclooxygenase 1 activity." | 1.30 | Inhibitory effect of Coptidis Rhizoma and Scutellariae Radix on azoxymethane-induced aberrant crypt foci formation in rat colon. ( Amagaya, S; Fukuda, K; Fukutake, M; Iizuka, A; Kawamura, H; Komatsu, Y; Yokota, S, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 15 (45.45) | 24.3611 |
| 2020's | 10 (30.30) | 2.80 |
| Authors | Studies |
|---|---|
| Nie, Q | 1 |
| Peng, WW | 1 |
| Wang, Y | 2 |
| Zhong, L | 1 |
| Zhang, X | 1 |
| Zeng, L | 1 |
| Liu, Y | 3 |
| Fang, X | 2 |
| Li, Y | 3 |
| Bing, L | 1 |
| Fang, J | 1 |
| Xian, X | 2 |
| Zhang, W | 3 |
| Li, J | 2 |
| Zhao, Z | 2 |
| Zhu, Y | 2 |
| Izadparast, F | 1 |
| Riahi-Zajani, B | 1 |
| Yarmohammadi, F | 1 |
| Hayes, AW | 1 |
| Karimi, G | 1 |
| Nathani, S | 3 |
| Mishra, R | 3 |
| Katiyar, P | 3 |
| Sircar, D | 3 |
| Roy, P | 3 |
| Sun, Q | 1 |
| Shan, R | 1 |
| Qi, T | 1 |
| Yang, P | 2 |
| Hua, W | 1 |
| Liu, C | 1 |
| Zou, J | 1 |
| Kwon, S | 1 |
| Chan, AT | 1 |
| Li, G | 1 |
| Zhang, C | 2 |
| Liang, W | 1 |
| Zhang, Y | 2 |
| Shen, Y | 1 |
| Tian, X | 1 |
| Wang, Z | 1 |
| Wang, L | 4 |
| Shi, B | 1 |
| Sun, X | 1 |
| Xie, Y | 2 |
| Yang, H | 1 |
| Zi, C | 1 |
| Wang, X | 2 |
| Sheng, J | 1 |
| Subair, TI | 1 |
| Soremekun, OS | 1 |
| Olotu, FA | 1 |
| Soliman, MES | 1 |
| Ruan, H | 1 |
| Zhan, YY | 2 |
| Hou, J | 1 |
| Xu, B | 1 |
| Chen, B | 1 |
| Tian, Y | 1 |
| Wu, D | 1 |
| Zhao, Y | 1 |
| Chen, X | 1 |
| Mi, P | 1 |
| Zhang, L | 2 |
| Zhang, S | 1 |
| Cao, H | 4 |
| Wang, H | 1 |
| Li, H | 1 |
| Su, Y | 1 |
| Zhang, XK | 1 |
| Hu, T | 4 |
| Mao, L | 1 |
| Chen, Q | 1 |
| Gong, K | 1 |
| Xu, X | 1 |
| Hong, X | 1 |
| Ghareeb, AE | 1 |
| Moawed, FSM | 1 |
| Ghareeb, DA | 1 |
| Kandil, EI | 1 |
| Lu, N | 1 |
| Liu, L | 2 |
| Wang, B | 1 |
| Israel, DA | 1 |
| Peek, RM | 1 |
| Polk, DB | 2 |
| Yan, F | 2 |
| Xu, LN | 1 |
| Lu, BN | 1 |
| Hu, MM | 1 |
| Xu, YW | 1 |
| Han, X | 1 |
| Qi, Y | 1 |
| Peng, JY | 1 |
| Yu, M | 1 |
| Tong, X | 1 |
| Qi, B | 1 |
| Qu, H | 1 |
| Dong, S | 1 |
| Yu, B | 1 |
| Zhang, N | 1 |
| Tang, N | 1 |
| Guamán Ortiz, LM | 2 |
| Tillhon, M | 1 |
| Parks, M | 1 |
| Dutto, I | 1 |
| Prosperi, E | 1 |
| Savio, M | 1 |
| Arcamone, AG | 1 |
| Buzzetti, F | 2 |
| Lombardi, P | 2 |
| Scovassi, AI | 2 |
| Croce, AL | 1 |
| Aredia, F | 1 |
| Sapienza, S | 1 |
| Fiorillo, G | 1 |
| Syeda, TM | 1 |
| Huang, C | 1 |
| Liu, H | 1 |
| Gong, XL | 1 |
| Wu, LY | 1 |
| Wen, B | 1 |
| La, X | 1 |
| Li, Z | 1 |
| Thirupurasundari, CJ | 1 |
| Padmini, R | 1 |
| Devaraj, SN | 1 |
| Wu, K | 2 |
| Yang, J | 1 |
| Zhou, Q | 2 |
| Yang, Q | 1 |
| Mu, Y | 1 |
| Zhou, L | 1 |
| He, B | 1 |
| Shi, Y | 1 |
| Chaturvedi, R | 1 |
| Calcutt, MW | 1 |
| Ren, X | 1 |
| Wilson, KT | 1 |
| Chidambara Murthy, KN | 1 |
| Jayaprakasha, GK | 1 |
| Patil, BS | 1 |
| Park, JJ | 1 |
| Seo, SM | 1 |
| Kim, EJ | 1 |
| Lee, YJ | 1 |
| Ko, YG | 1 |
| Ha, J | 1 |
| Lee, M | 1 |
| Hsu, WH | 1 |
| Hsieh, YS | 1 |
| Kuo, HC | 1 |
| Teng, CY | 1 |
| Huang, HI | 1 |
| Wang, CJ | 1 |
| Yang, SF | 1 |
| Liou, YS | 1 |
| Kuo, WH | 1 |
| Fukutake, M | 1 |
| Yokota, S | 1 |
| Kawamura, H | 1 |
| Iizuka, A | 1 |
| Amagaya, S | 1 |
| Fukuda, K | 2 |
| Komatsu, Y | 1 |
| Hibiya, Y | 1 |
| Mutoh, M | 1 |
| Koshiji, M | 1 |
| Akao, S | 1 |
| Fujiwara, H | 1 |
| Lin, JG | 1 |
| Chung, JG | 1 |
| Wu, LT | 1 |
| Chen, GW | 1 |
| Chang, HL | 1 |
| Wang, TF | 1 |
| Lin, HL | 1 |
| Liu, TY | 1 |
| Wu, CW | 1 |
| Chi, CW | 1 |
| Iwasa, K | 1 |
| Moriyasu, M | 1 |
| Yamori, T | 1 |
| Turuo, T | 1 |
| Lee, DU | 1 |
| Wiegrebe, W | 1 |
| Iizuka, N | 1 |
| Hazama, S | 1 |
| Yoshimura, K | 1 |
| Yoshino, S | 1 |
| Tangoku, A | 1 |
| Miyamoto, K | 1 |
| Okita, K | 1 |
| Oka, M | 1 |
1 review available for berberine and Colonic Neoplasms
| Article | Year |
|---|---|
Protective effect of berberine against LPS-induced injury in the intestine: a review.
Topics: Adenocarcinoma; Animals; Berberine; Caco-2 Cells; Colonic Neoplasms; Cyclooxygenase 2; Humans; Intes | 2022 |
32 other studies available for berberine and Colonic Neoplasms
| Article | Year |
|---|---|
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Topics: Aged; Animals; Berberine; beta Catenin; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; | 2022 |
Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding proteins cleavage-activating protein ubiquitination.
Topics: Berberine; Colonic Neoplasms; Humans; Leukemia; Lipids; Lipogenesis; Sterols; Ubiquitination; Zinc F | 2022 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells.
Topics: Annexin A5; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Clusterin; Colonic Neoplasms | 2023 |
Berberine Reverses the Tumorigenic Function of Colon Cancer Cell-Derived Exosomes.
Topics: Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Exosomes; HCT116 | 2023 |
Berberine suppresses colon cancer cell proliferation by inhibiting the SCAP/SREBP-1 signaling pathway-mediated lipogenesis.
Topics: Antineoplastic Agents, Phytogenic; Berberine; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Co | 2020 |
Extracting the benefits of berberine for colorectal cancer.
Topics: Adenoma; Antineoplastic Agents, Phytogenic; Aspirin; Berberine; Cardiovascular Diseases; Case-Contro | 2020 |
Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Benzoquinones; Berberine; Colonic Neoplasms; Dose-Response Relati | 2021 |
Demethyleneberberine promotes apoptosis and suppresses TGF-β/Smads induced EMT in the colon cancer cells HCT-116.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Cell Proliferation; Cell Survival; Colonic Neoplasms; D | 2021 |
Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer.
Topics: Berberine; Catalytic Domain; Colonic Neoplasms; Humans; Hydrogen Bonding; Molecular Targeted Therapy | 2021 |
Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells.
Topics: Animals; Berberine; beta Catenin; Colonic Neoplasms; Humans; Mice; Mice, Inbred BALB C; Retinoid X R | 2017 |
Berberine decelerates glucose metabolism via suppression of mTOR‑dependent HIF‑1α protein synthesis in colon cancer cells.
Topics: Berberine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Gene Expression | 2018 |
Potential Prophylactic Effect of Berberine against Rat Colon Carcinoma Induce by 1,2-Dimethyl Hydrazine
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Apoptosis; Berberine; Carcinogens; Cell Proliferation; | 2018 |
Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Topics: Animals; Antineoplastic Agents; Berberine; Cell Cycle Checkpoints; Cell Proliferation; Colonic Neopl | 2013 |
Mechanisms involved in the cytotoxic effects of berberine on human colon cancer HCT-8 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Berberine; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; F | 2012 |
Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NF‑κB.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Berberine; Camptothe | 2014 |
Multiple effects of berberine derivatives on colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Berberine; Cell Proliferation; Colonic Neoplasms; HCT11 | 2014 |
Effect of new berberine derivatives on colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms | 2015 |
Effect of evodiamine and berberine on the interaction between DNMTs and target microRNAs during malignant transformation of the colon by TGF-β1.
Topics: Animals; Animals, Newborn; Berberine; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; DNA | 2017 |
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
Topics: Activating Transcription Factor 6; Apoptosis; Autophagy; Berberine; Biomarkers, Tumor; Carcinoma, He | 2017 |
Effect of berberine on the antioxidant status, ultrastructural modifications and protein bound carbohydrates in azoxymethane-induced colon cancer in rats.
Topics: Animals; Antioxidants; Azoxymethane; Berberine; Blood Proteins; Carbohydrate Metabolism; Carcinogens | 2009 |
[Preventive effects of berberine on experimental colon cancer and relationship with cyclooxygenase-2 expression].
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Berberine; Body Weight; Colonic Neoplasms; Cycl | 2010 |
Berberine inhibits the proliferation of colon cancer cells by inactivating Wnt/β-catenin signaling.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Berb | 2012 |
Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis Inducing Factor; Berberine | 2012 |
The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells.
Topics: Berberine; Biological Products; Caspase 8; Cell Death; Cell Line, Tumor; Cell Proliferation; Colonic | 2012 |
Berberine inhibits human colon cancer cell migration via AMP-activated protein kinase-mediated downregulation of integrin β1 signaling.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Berberine; Cell Movement; Colonic Neoplasms; D | 2012 |
Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Topics: Apoptosis; bcl-X Protein; Berberine; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Caspas | 2007 |
Inhibitory effect of Coptidis Rhizoma and Scutellariae Radix on azoxymethane-induced aberrant crypt foci formation in rat colon.
Topics: Animals; Azoxymethane; Berberine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; M | 1998 |
Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells.
Topics: Berberine; Cell Division; Colonic Neoplasms; Cycloheximide; Cyclooxygenase 2; Genes, Reporter; Human | 1999 |
Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells.
Topics: 4-Aminobenzoic Acid; Adenocarcinoma; Aflatoxins; Arylamine N-Acetyltransferase; Berberine; Carcinoge | 1999 |
Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Carcinoma; C | 1999 |
In vitro cytotoxicity of the protoberberine-type alkaloids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast | 2001 |
Anticachectic effects of the natural herb Coptidis rhizoma and berberine on mice bearing colon 26/clone 20 adenocarcinoma.
Topics: Adenocarcinoma; Adipose Tissue; Animals; Berberine; Cachexia; Colonic Neoplasms; Coptis chinensis; D | 2002 |