berberine has been researched along with Cardiovascular Stroke in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aimed to test the hypothesis that berberine, a plant-derived anti-oxidant, attenuates adverse left ventricular remodelling and improves cardiac function in a rat model of myocardial infarction (MI)." | 7.80 | Berberine attenuates adverse left ventricular remodeling and cardiac dysfunction after acute myocardial infarction in rats: role of autophagy. ( Bourantas, CV; Chen, SL; Iqbal, J; Li, JJ; Li, MH; Mi, QY; Tian, NL; Yang, SH; Yu, YH; Zhang, YJ; Zhao, SL, 2014) |
| "Coptisine exerts pronounced cardioprotection in rats subjected to myocardial I/R likely through suppressing myocardial apoptosis and inflammation by inhibiting the Rho/ROCK pathway." | 7.79 | Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation. ( Du, GH; Fang, LH; Gong, LL; Guo, J; Li, L; Qin, HL; Wang, SB; Wu, YJ; Xu, XN; Yan, Y; Yuan, TY, 2013) |
| "The present study was designed to elucidate the potential mechanism underlying that berberine suppressed ischemic arrhythmias in a rat model of diabetes mellitus (DM)." | 7.78 | Berberine alleviates ischemic arrhythmias via recovering depressed I(to) and I(Ca) currents in diabetic rats. ( Fu, Y; Li, Q; Li, XL; Shan, HL; Sun, YQ; Wang, LH; Yu, HJ; Zhang, L, 2012) |
| "Myocardial infarction was produced in rats with 85 mgkg(-1) isoproterenol administered subcutaneously twice at an interval of 24 h." | 7.78 | Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. ( Du, GH; Fang, LH; Gong, LL; Li, XX; Qin, HL; Sun, JL; Wang, SB, 2012) |
| "The purpose of this study was to explore the anti-arrhythmic mechanisms of berberine in diabetic rats with myocardial infarction." | 7.77 | Berberine elicits anti-arrhythmic effects via IK1/Kir2.1 in the rat type 2 diabetic myocardial infarction model. ( Fu, Y; Li, Q; Sun, YQ; Wang, LH; Yu, CH, 2011) |
| ", l-tetrahydropalmatine (THP), l-stepholidine (SPD), and tetrahydroberberine (THB) on experimental myocardial infarction by ligating the left coronary artery were estimated in rats." | 7.68 | [Protective effects of tetrahydroprotoberberines on experimental myocardial infarction in rats]. ( Li, DX; Wang, W; Xuan, B, 1992) |
| "The effects of berberine (Ber 5 mg/kg iv) on ventricular tachyarrhythmias and electrophysiologic consequences in both normal and ischemic myocardium were studied in the open-chest dogs subjected to programmed electrical stimulation (PES) and intimal surface anodal direct current stimulation of the circumflex coronary artery on 5-8 d after acute myocardial infarction." | 7.67 | [Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction]. ( Cao, HY; Li, Q; Xu, Z, 1989) |
| "Berberine (BBR) is a monomer compound with various biological functions." | 5.91 | Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β-catenin pathway in the myocardium of mice after myocardial infarction. ( Dong, YL; Gui, Y; Hu, DS; Jiang, F; Kang, ZY; Li, MY; Lin, L; Luo, SS; Qin, RJ; Sarapultsev, A; Shuai, XX; Tian, CX; Wu, B; Zhang, ZL, 2023) |
| "Berberine is a isoquinoline quarternary alkaloid from plants that has been associated with anti-inflammatory, anti-oxidative, and cardioprotective properties." | 5.46 | Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction. ( Allijn, IE; Chong, SY; Czarny, BMS; da Silva, AE; de Kleijn, DPV; Lam, CSP; Metselaar, JM; Pastorin, G; Schiffelers, RM; Storm, G; Wang, JW; Wang, X; Weiler, M, 2017) |
| "The present study aimed to test the hypothesis that berberine, a plant-derived anti-oxidant, attenuates adverse left ventricular remodelling and improves cardiac function in a rat model of myocardial infarction (MI)." | 3.80 | Berberine attenuates adverse left ventricular remodeling and cardiac dysfunction after acute myocardial infarction in rats: role of autophagy. ( Bourantas, CV; Chen, SL; Iqbal, J; Li, JJ; Li, MH; Mi, QY; Tian, NL; Yang, SH; Yu, YH; Zhang, YJ; Zhao, SL, 2014) |
| "Coptisine exerts pronounced cardioprotection in rats subjected to myocardial I/R likely through suppressing myocardial apoptosis and inflammation by inhibiting the Rho/ROCK pathway." | 3.79 | Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation. ( Du, GH; Fang, LH; Gong, LL; Guo, J; Li, L; Qin, HL; Wang, SB; Wu, YJ; Xu, XN; Yan, Y; Yuan, TY, 2013) |
| "The present study was designed to elucidate the potential mechanism underlying that berberine suppressed ischemic arrhythmias in a rat model of diabetes mellitus (DM)." | 3.78 | Berberine alleviates ischemic arrhythmias via recovering depressed I(to) and I(Ca) currents in diabetic rats. ( Fu, Y; Li, Q; Li, XL; Shan, HL; Sun, YQ; Wang, LH; Yu, HJ; Zhang, L, 2012) |
| "Myocardial infarction was produced in rats with 85 mgkg(-1) isoproterenol administered subcutaneously twice at an interval of 24 h." | 3.78 | Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. ( Du, GH; Fang, LH; Gong, LL; Li, XX; Qin, HL; Sun, JL; Wang, SB, 2012) |
| "The purpose of this study was to explore the anti-arrhythmic mechanisms of berberine in diabetic rats with myocardial infarction." | 3.77 | Berberine elicits anti-arrhythmic effects via IK1/Kir2.1 in the rat type 2 diabetic myocardial infarction model. ( Fu, Y; Li, Q; Sun, YQ; Wang, LH; Yu, CH, 2011) |
| ", l-tetrahydropalmatine (THP), l-stepholidine (SPD), and tetrahydroberberine (THB) on experimental myocardial infarction by ligating the left coronary artery were estimated in rats." | 3.68 | [Protective effects of tetrahydroprotoberberines on experimental myocardial infarction in rats]. ( Li, DX; Wang, W; Xuan, B, 1992) |
| "The effects of berberine (Ber 5 mg/kg iv) on ventricular tachyarrhythmias and electrophysiologic consequences in both normal and ischemic myocardium were studied in the open-chest dogs subjected to programmed electrical stimulation (PES) and intimal surface anodal direct current stimulation of the circumflex coronary artery on 5-8 d after acute myocardial infarction." | 3.67 | [Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction]. ( Cao, HY; Li, Q; Xu, Z, 1989) |
| "Fibrosis is a general term encompassing a plethora of pathologies that span all systems and is marked by increased deposition of collagen." | 2.53 | AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. ( Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S, 2016) |
| "Berberine (BBR) is a monomer compound with various biological functions." | 1.91 | Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β-catenin pathway in the myocardium of mice after myocardial infarction. ( Dong, YL; Gui, Y; Hu, DS; Jiang, F; Kang, ZY; Li, MY; Lin, L; Luo, SS; Qin, RJ; Sarapultsev, A; Shuai, XX; Tian, CX; Wu, B; Zhang, ZL, 2023) |
| "Berberine has several preventive effects on cardiovascular diseases." | 1.46 | Berberine promotes ischemia-induced angiogenesis in mice heart via upregulation of microRNA-29b. ( Jian, X; Li, P; Ping, S; Wan, GR; Yin, YL; Yu, HY; Zhu, ML, 2017) |
| "Berberine is a isoquinoline quarternary alkaloid from plants that has been associated with anti-inflammatory, anti-oxidative, and cardioprotective properties." | 1.46 | Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction. ( Allijn, IE; Chong, SY; Czarny, BMS; da Silva, AE; de Kleijn, DPV; Lam, CSP; Metselaar, JM; Pastorin, G; Schiffelers, RM; Storm, G; Wang, JW; Wang, X; Weiler, M, 2017) |
| "Berberine treatment decreased infarct size and diminished the duration and incidence of arrhythmias compared to controls." | 1.38 | Berberine attenuates ischemia-reperfusion injury via regulation of adenosine-5'-monophosphate kinase activity in both non-ischemic and ischemic areas of the rat heart. ( Chang, W; Chen, L; Hatch, GM; Li, J; Meng, Z; Wang, C; Wei, S; Xiao, D; Zhang, M, 2012) |
| "A suppression of arrhythmia by Pro and CPU86017 resulted from a regression of the dispersion and depression of RyR2 and SERCA2." | 1.32 | Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats. ( Dai, DZ; Gao, E; Lu, F; Wang, HL; Zhang, YP, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, CX | 1 |
| Li, MY | 1 |
| Shuai, XX | 1 |
| Jiang, F | 1 |
| Dong, YL | 1 |
| Gui, Y | 1 |
| Zhang, ZL | 1 |
| Qin, RJ | 1 |
| Kang, ZY | 1 |
| Lin, L | 1 |
| Sarapultsev, A | 1 |
| Wu, B | 1 |
| Luo, SS | 1 |
| Hu, DS | 1 |
| Long, T | 3 |
| Pan, W | 3 |
| Li, F | 3 |
| Sheikh, SA | 3 |
| Xie, Q | 3 |
| Zhang, C | 3 |
| Zhu, ML | 1 |
| Yin, YL | 1 |
| Ping, S | 1 |
| Yu, HY | 1 |
| Wan, GR | 1 |
| Jian, X | 1 |
| Li, P | 1 |
| Guo, J | 1 |
| Wang, SB | 3 |
| Yuan, TY | 1 |
| Wu, YJ | 1 |
| Yan, Y | 1 |
| Li, L | 1 |
| Xu, XN | 1 |
| Gong, LL | 2 |
| Qin, HL | 2 |
| Fang, LH | 2 |
| Du, GH | 2 |
| Zhang, YJ | 1 |
| Yang, SH | 1 |
| Li, MH | 1 |
| Iqbal, J | 1 |
| Bourantas, CV | 1 |
| Mi, QY | 1 |
| Yu, YH | 1 |
| Li, JJ | 1 |
| Zhao, SL | 1 |
| Tian, NL | 1 |
| Chen, SL | 1 |
| Yue, Y | 1 |
| Dou, L | 1 |
| Wang, X | 2 |
| Xue, H | 1 |
| Song, Y | 1 |
| Li, X | 1 |
| Daskalopoulos, EP | 1 |
| Dufeys, C | 1 |
| Bertrand, L | 1 |
| Beauloye, C | 1 |
| Horman, S | 1 |
| Yu, L | 1 |
| Li, Q | 4 |
| Yu, B | 1 |
| Yang, Y | 1 |
| Jin, Z | 1 |
| Duan, W | 1 |
| Zhao, G | 1 |
| Zhai, M | 1 |
| Liu, L | 1 |
| Yi, D | 1 |
| Chen, M | 1 |
| Yu, S | 1 |
| Zhao, GL | 1 |
| Yu, LM | 1 |
| Gao, WL | 1 |
| Duan, WX | 1 |
| Jiang, B | 1 |
| Liu, XD | 1 |
| Zhang, B | 1 |
| Liu, ZH | 1 |
| Zhai, ME | 1 |
| Jin, ZX | 1 |
| Yu, SQ | 1 |
| Wang, Y | 1 |
| Chang, W | 2 |
| Li, K | 1 |
| Guan, F | 1 |
| Yao, F | 1 |
| Yu, Y | 1 |
| Zhang, M | 2 |
| Hatch, GM | 2 |
| Chen, L | 2 |
| Allijn, IE | 1 |
| Czarny, BMS | 1 |
| Chong, SY | 1 |
| Weiler, M | 1 |
| da Silva, AE | 1 |
| Metselaar, JM | 1 |
| Lam, CSP | 1 |
| Pastorin, G | 1 |
| de Kleijn, DPV | 1 |
| Storm, G | 1 |
| Wang, JW | 1 |
| Schiffelers, RM | 1 |
| Wang, LH | 2 |
| Yu, CH | 1 |
| Fu, Y | 2 |
| Sun, YQ | 2 |
| Li, XL | 1 |
| Yu, HJ | 1 |
| Zhang, L | 1 |
| Shan, HL | 1 |
| Sun, JL | 1 |
| Li, XX | 1 |
| Li, J | 1 |
| Meng, Z | 1 |
| Xiao, D | 1 |
| Wei, S | 1 |
| Wang, C | 1 |
| Wang, HL | 1 |
| Dai, DZ | 2 |
| Gao, E | 1 |
| Zhang, YP | 1 |
| Lu, F | 1 |
| Xuan, B | 1 |
| Li, DX | 1 |
| Wang, W | 1 |
| Xu, Z | 1 |
| Cao, HY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Therapeutic Effects of Combination of Insulin With Berberine on the Patients With Stess Hyperlipemia:a Prospective, Double Blind, Randomized, Placebo-controlled, Single-center Clinical Trial[NCT02806999] | Phase 4 | 200 participants (Anticipated) | Interventional | 2016-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for berberine and Cardiovascular Stroke
| Article | Year |
|---|---|
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracell | 2016 |
Vulnerable substrate and multiple ion channel disorder in a diseased heart will be new targets for antiarrhythmic therapy.
Topics: Animals; Anti-Arrhythmia Agents; Berberine; Cardiomegaly; Humans; Ion Channels; Long QT Syndrome; My | 2000 |
17 other studies available for berberine and Cardiovascular Stroke
| Article | Year |
|---|---|
Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β-catenin pathway in the myocardium of mice after myocardial infarction.
Topics: Animals; Berberine; beta Catenin; Macrophages; Mice; Myocardial Infarction; Myocardium; Myocytes, Ca | 2023 |
Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion from HMGB1-mediated inflammatory injury.
Topics: Animals; Berberine; Coronary Artery Disease; HMGB1 Protein; Inflammation; MicroRNAs; Myocardial Infa | 2023 |
Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion from HMGB1-mediated inflammatory injury.
Topics: Animals; Berberine; Coronary Artery Disease; HMGB1 Protein; Inflammation; MicroRNAs; Myocardial Infa | 2023 |
Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion from HMGB1-mediated inflammatory injury.
Topics: Animals; Berberine; Coronary Artery Disease; HMGB1 Protein; Inflammation; MicroRNAs; Myocardial Infa | 2023 |
Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion from HMGB1-mediated inflammatory injury.
Topics: Animals; Berberine; Coronary Artery Disease; HMGB1 Protein; Inflammation; MicroRNAs; Myocardial Infa | 2023 |
Berberine promotes ischemia-induced angiogenesis in mice heart via upregulation of microRNA-29b.
Topics: AMP-Activated Protein Kinases; Angiogenesis Inducing Agents; Animals; Berberine; Cell Proliferation; | 2017 |
Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation.
Topics: Animals; Apoptosis; Berberine; Cytokines; Disease Models, Animal; Electrocardiography; Enzyme-Linked | 2013 |
Berberine attenuates adverse left ventricular remodeling and cardiac dysfunction after acute myocardial infarction in rats: role of autophagy.
Topics: Animals; Autophagy; Berberine; Echocardiography; Myocardial Infarction; Myocytes, Cardiac; p38 Mitog | 2014 |
Screening β1AR inhibitors by cell membrane chromatography and offline UPLC/MS method for protecting myocardial ischemia.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Apoptosis; Berberine; Binding, Competitive; Cell Me | 2015 |
Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzamides; Berberine; Caspase 3; Cell Line; Cell Su | 2016 |
Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Berberine; Cardiotonic Agents; Cell Line; Endoplasmic Reticulum Stress; Janus Ki | 2016 |
Berberine Pretreatment Confers Cardioprotection Against Ischemia-Reperfusion Injury in a Rat Model of Type 2 Diabetes.
Topics: AMP-Activated Protein Kinases; Animals; Arrhythmias, Cardiac; Berberine; Biomarkers; Blood Glucose; | 2016 |
Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction.
Topics: Animals; Anti-Inflammatory Agents; Berberine; Cardiotonic Agents; Heart; Interleukin-6; Liposomes; M | 2017 |
Berberine elicits anti-arrhythmic effects via IK1/Kir2.1 in the rat type 2 diabetic myocardial infarction model.
Topics: Animals; Anti-Arrhythmia Agents; Berberine; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; | 2011 |
Berberine alleviates ischemic arrhythmias via recovering depressed I(to) and I(Ca) currents in diabetic rats.
Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Berberine; Calcium; Calcium Channels, L-Type; C | 2012 |
Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Berberine; Cardioto | 2012 |
Berberine attenuates ischemia-reperfusion injury via regulation of adenosine-5'-monophosphate kinase activity in both non-ischemic and ischemic areas of the rat heart.
Topics: Adenine Nucleotides; Adenylate Kinase; Animals; Berberine; Blotting, Western; Hemodynamics; Hypertro | 2012 |
Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Berberine; Calcium Channels, L-Type; Calcium- | 2004 |
[Protective effects of tetrahydroprotoberberines on experimental myocardial infarction in rats].
Topics: Alkaloids; Animals; Aspartate Aminotransferases; Berberine; Berberine Alkaloids; Creatine Kinase; Fe | 1992 |
[Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction].
Topics: Animals; Berberine; Berberine Alkaloids; Dogs; Female; Male; Myocardial Infarction; Procainamide; Ve | 1989 |