berberine has been researched along with Cardiomegaly in 9 studies
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to investigate the effect of berberine on catecholamine level (adrenaline and noradrenaline) in rats with experimental cardiac hypertrophy." | 7.72 | Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy. ( Chan, BT; Hong, Y; Hou, J; Hui, SS, 2003) |
| "To assess the effects of berberine on cardiac hypertrophy induceded by L-thyroxine(L-Thy) in rats." | 7.72 | [Protective effect of berberine on cardiac hypertrophy induced by L-thyroxine in rats]. ( Xu, JG; Yang, J; Zhou, ZY, 2004) |
| "Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also an important risk for developing heart failure." | 5.40 | Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. ( Chen, SL; Iqbal, J; Li, B; Li, MH; Mao, WX; Mi, QY; Wang, ZM; Xie, HG; Yang, SH; Yu, YH; Zhang, YJ, 2014) |
| " We hypothesized that CPU86017, derived from berberine, which possesses multi-channel blocking activity, could suppress inflammatory factors, resulting in inhibition of over-expression of ether-a-go-go (ERG) and an augmented incidence of ventricular fibrillation (VF) in ischaemia/reperfusion (I/R)." | 3.74 | Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent. ( Dai, DZ; Dai, Y; Du, RH; Tang, WH; Yi, HW, 2008) |
| "The aim of this study is to investigate the effect of berberine on catecholamine level (adrenaline and noradrenaline) in rats with experimental cardiac hypertrophy." | 3.72 | Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy. ( Chan, BT; Hong, Y; Hou, J; Hui, SS, 2003) |
| "To assess the effects of berberine on cardiac hypertrophy induceded by L-thyroxine(L-Thy) in rats." | 3.72 | [Protective effect of berberine on cardiac hypertrophy induced by L-thyroxine in rats]. ( Xu, JG; Yang, J; Zhou, ZY, 2004) |
| "Fibrosis is a general term encompassing a plethora of pathologies that span all systems and is marked by increased deposition of collagen." | 2.53 | AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. ( Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S, 2016) |
| "Pathological cardiac hypertrophy is regarded as a critical intermediate step toward the development of heart failure." | 1.42 | Smad3 Couples Pak1 With the Antihypertrophic Pathway Through the E3 Ubiquitin Ligase, Fbxo32. ( Cartwright, EJ; Chowdhury, SK; Lei, M; Liang, Q; Liu, W; Prehar, S; Tsui, H; Wang, S; Wang, X; Zi, M, 2015) |
| "Berberine treatment of palmitate-incubated H9c2 cells reduced hypertrophy, increased α-MHC expression and decreased β-MHC expression." | 1.42 | Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells. ( Chang, W; Chen, L; Hatch, GM; Meng, Z; Yao, F; Yu, Y; Zhang, M, 2015) |
| "Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also an important risk for developing heart failure." | 1.40 | Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. ( Chen, SL; Iqbal, J; Li, B; Li, MH; Mao, WX; Mi, QY; Wang, ZM; Xie, HG; Yang, SH; Yu, YH; Zhang, YJ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeng, Z | 1 |
| Pan, Y | 1 |
| Wu, W | 1 |
| Li, L | 1 |
| Wu, Z | 1 |
| Zhang, Y | 1 |
| Deng, B | 1 |
| Wei, S | 1 |
| Zhang, W | 1 |
| Lin, F | 1 |
| Song, Y | 1 |
| Li, MH | 1 |
| Zhang, YJ | 1 |
| Yu, YH | 1 |
| Yang, SH | 1 |
| Iqbal, J | 1 |
| Mi, QY | 1 |
| Li, B | 1 |
| Wang, ZM | 1 |
| Mao, WX | 1 |
| Xie, HG | 1 |
| Chen, SL | 1 |
| Tsui, H | 1 |
| Zi, M | 1 |
| Wang, S | 1 |
| Chowdhury, SK | 1 |
| Prehar, S | 1 |
| Liang, Q | 1 |
| Cartwright, EJ | 1 |
| Lei, M | 1 |
| Liu, W | 1 |
| Wang, X | 1 |
| Chang, W | 1 |
| Zhang, M | 1 |
| Meng, Z | 1 |
| Yu, Y | 1 |
| Yao, F | 1 |
| Hatch, GM | 1 |
| Chen, L | 1 |
| Daskalopoulos, EP | 1 |
| Dufeys, C | 1 |
| Bertrand, L | 1 |
| Beauloye, C | 1 |
| Horman, S | 1 |
| Du, RH | 1 |
| Yi, HW | 1 |
| Dai, DZ | 2 |
| Tang, WH | 1 |
| Dai, Y | 1 |
| Hong, Y | 1 |
| Hui, SS | 1 |
| Chan, BT | 1 |
| Hou, J | 1 |
| Yang, J | 1 |
| Zhou, ZY | 1 |
| Xu, JG | 1 |
2 reviews available for berberine and Cardiomegaly
| Article | Year |
|---|---|
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracell | 2016 |
Vulnerable substrate and multiple ion channel disorder in a diseased heart will be new targets for antiarrhythmic therapy.
Topics: Animals; Anti-Arrhythmia Agents; Berberine; Cardiomegaly; Humans; Ion Channels; Long QT Syndrome; My | 2000 |
7 other studies available for berberine and Cardiomegaly
| Article | Year |
|---|---|
Myocardial hypertrophy is improved with berberine treatment via long non-coding RNA MIAT-mediated autophagy.
Topics: Animals; Autophagy; Berberine; Cardiomegaly; Disease Models, Animal; Down-Regulation; Male; Myocytes | 2019 |
Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy.
Topics: Animals; Arterial Pressure; Autophagy; Berberine; Blotting, Western; Body Weight; Cardiomegaly; Card | 2014 |
Smad3 Couples Pak1 With the Antihypertrophic Pathway Through the E3 Ubiquitin Ligase, Fbxo32.
Topics: Animals; Animals, Newborn; Aorta; Berberine; Cardiomegaly; Cells, Cultured; Constriction, Pathologic | 2015 |
Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Cardiomegaly; Cell Line; Diabetes Mellitus, Type | 2015 |
Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Aspartic Acid Endopeptidases; Berberine; Cardiomegaly | 2008 |
Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy.
Topics: Animals; Aorta, Abdominal; Berberine; Cardiomegaly; Catecholamines; Chromatography, High Pressure Li | 2003 |
[Protective effect of berberine on cardiac hypertrophy induced by L-thyroxine in rats].
Topics: Animals; Berberine; Calcium-Transporting ATPases; Cardiomegaly; Female; Male; Protein Subunits; Rats | 2004 |