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berberine and Cardiac Remodeling, Ventricular

berberine has been researched along with Cardiac Remodeling, Ventricular in 11 studies

Research Excerpts

ExcerptRelevanceReference
"The present study aimed to test the hypothesis that berberine, a plant-derived anti-oxidant, attenuates adverse left ventricular remodelling and improves cardiac function in a rat model of myocardial infarction (MI)."7.80Berberine attenuates adverse left ventricular remodeling and cardiac dysfunction after acute myocardial infarction in rats: role of autophagy. ( Bourantas, CV; Chen, SL; Iqbal, J; Li, JJ; Li, MH; Mi, QY; Tian, NL; Yang, SH; Yu, YH; Zhang, YJ; Zhao, SL, 2014)
"Emerging evidence indicates that leptin may be a potential new target in chronic heart failure (CHF) treatment."7.74Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017. ( Dai, DZ; Dai, Y; Na, T; Tang, XY, 2007)
"Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function."5.51Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats. ( Che, Y; Jin, YG; Shen, DF; Wang, SS; Wang, ZP; Wu, QQ; Yuan, Y, 2019)
"Berberine is a isoquinoline quarternary alkaloid from plants that has been associated with anti-inflammatory, anti-oxidative, and cardioprotective properties."5.46Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction. ( Allijn, IE; Chong, SY; Czarny, BMS; da Silva, AE; de Kleijn, DPV; Lam, CSP; Metselaar, JM; Pastorin, G; Schiffelers, RM; Storm, G; Wang, JW; Wang, X; Weiler, M, 2017)
"Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also an important risk for developing heart failure."5.40Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. ( Chen, SL; Iqbal, J; Li, B; Li, MH; Mao, WX; Mi, QY; Wang, ZM; Xie, HG; Yang, SH; Yu, YH; Zhang, YJ, 2014)
"Compared with the sham group, rats of the TAC group showed significantly increased cardiac hypertrophy and fibrosis, which could be ameliorated by treatment with berberine."3.96Berberine Attenuates Cardiac Hypertrophy Through Inhibition of mTOR Signaling Pathway. ( Chen, J; Chen, X; Cheng, C; Huang, S; Jiang, X; Liu, S; Xu, M, 2020)
"The present study aimed to test the hypothesis that berberine, a plant-derived anti-oxidant, attenuates adverse left ventricular remodelling and improves cardiac function in a rat model of myocardial infarction (MI)."3.80Berberine attenuates adverse left ventricular remodeling and cardiac dysfunction after acute myocardial infarction in rats: role of autophagy. ( Bourantas, CV; Chen, SL; Iqbal, J; Li, JJ; Li, MH; Mi, QY; Tian, NL; Yang, SH; Yu, YH; Zhang, YJ; Zhao, SL, 2014)
"Remodeling of the pulmonary artery is a major feature of pulmonary artery hypertension, and CPU86017, a derivative of berberine, is known to effectively alleviate hypoxic pulmonary hypertension (HPH)."3.74CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation. ( Dai, DZ; Dai, Y; Li, N, 2008)
"Emerging evidence indicates that leptin may be a potential new target in chronic heart failure (CHF) treatment."3.74Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017. ( Dai, DZ; Dai, Y; Na, T; Tang, XY, 2007)
"Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function."1.51Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats. ( Che, Y; Jin, YG; Shen, DF; Wang, SS; Wang, ZP; Wu, QQ; Yuan, Y, 2019)
"Berberine is a isoquinoline quarternary alkaloid from plants that has been associated with anti-inflammatory, anti-oxidative, and cardioprotective properties."1.46Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction. ( Allijn, IE; Chong, SY; Czarny, BMS; da Silva, AE; de Kleijn, DPV; Lam, CSP; Metselaar, JM; Pastorin, G; Schiffelers, RM; Storm, G; Wang, JW; Wang, X; Weiler, M, 2017)
"Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also an important risk for developing heart failure."1.40Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. ( Chen, SL; Iqbal, J; Li, B; Li, MH; Mao, WX; Mi, QY; Wang, ZM; Xie, HG; Yang, SH; Yu, YH; Zhang, YJ, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Che, Y1
Shen, DF1
Wang, ZP1
Jin, YG1
Wu, QQ1
Wang, SS1
Yuan, Y1
Chen, X1
Jiang, X1
Cheng, C1
Chen, J1
Huang, S1
Xu, M1
Liu, S1
Ding, L1
Li, S2
Wang, F1
Xu, J1
Wang, B1
Kou, J1
Wang, Y1
Cao, W1
Li, G1
Xing, W1
Zhang, M1
Geng, F1
Yang, H1
Zhang, H1
Zhang, X1
Li, J1
Dong, L1
Gao, F1
Li, MH2
Zhang, YJ2
Yu, YH2
Yang, SH2
Iqbal, J2
Mi, QY2
Li, B1
Wang, ZM1
Mao, WX1
Xie, HG1
Chen, SL2
Bourantas, CV1
Li, JJ1
Zhao, SL1
Tian, NL1
Allijn, IE1
Czarny, BMS1
Wang, X1
Chong, SY1
Weiler, M1
da Silva, AE1
Metselaar, JM1
Lam, CSP1
Pastorin, G1
de Kleijn, DPV1
Storm, G1
Wang, JW1
Schiffelers, RM1
Li, N1
Dai, DZ2
Dai, Y2
Carlomagno, G1
Pirozzi, C1
Mercurio, V1
Ruvolo, A1
Fazio, S1
Na, T1
Tang, XY1
Zhao, HP1
Hong, Y1
Xie, JD1
Xie, XR1
Wang, J1
Fan, JB1

Trials

1 trial available for berberine and Cardiac Remodeling, Ventricular

ArticleYear
Effects of a nutraceutical combination on left ventricular remodeling and vasoreactivity in subjects with the metabolic syndrome.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2012, Volume: 22, Issue:5

    Topics: Anticholesteremic Agents; Berberine; Cardiotonic Agents; Dietary Supplements; Fatty Alcohols; Female

2012

Other Studies

10 other studies available for berberine and Cardiac Remodeling, Ventricular

ArticleYear
Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats.
    BMC cardiovascular disorders, 2019, 10-15, Volume: 19, Issue:1

    Topics: Animals; Berberine; Cardiomyopathies; Cell Transdifferentiation; Cells, Cultured; Coculture Techniqu

2019
Berberine Attenuates Cardiac Hypertrophy Through Inhibition of mTOR Signaling Pathway.
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:4

    Topics: Animals; Atrial Natriuretic Factor; Berberine; Cell Line; Disease Models, Animal; Fibrosis; Hypertro

2020
Berberine improves dietary-induced cardiac remodeling by upregulating Kruppel-like factor 4-dependent mitochondrial function.
    Biological chemistry, 2021, 06-25, Volume: 402, Issue:7

    Topics: Animals; Berberine; Dietary Supplements; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors;

2021
Antifibrotic cardioprotection of berberine via downregulating myocardial IGF-1 receptor-regulated MMP-2/MMP-9 expression in diabetic rats.
    American journal of physiology. Heart and circulatory physiology, 2018, 10-01, Volume: 315, Issue:4

    Topics: Actins; Animals; Berberine; Blood Glucose; Cell Differentiation; Cell Proliferation; Cells, Cultured

2018
Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy.
    European journal of pharmacology, 2014, Apr-05, Volume: 728

    Topics: Animals; Arterial Pressure; Autophagy; Berberine; Blotting, Western; Body Weight; Cardiomegaly; Card

2014
Berberine attenuates adverse left ventricular remodeling and cardiac dysfunction after acute myocardial infarction in rats: role of autophagy.
    Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:12

    Topics: Animals; Autophagy; Berberine; Echocardiography; Myocardial Infarction; Myocytes, Cardiac; p38 Mitog

2014
Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 02-10, Volume: 247

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Cardiotonic Agents; Heart; Interleukin-6; Liposomes; M

2017
CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:5

    Topics: Animals; Berberine; Extracellular Matrix; Gene Expression Regulation; Hypertension, Pulmonary; Hypox

2008
Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:1

    Topics: Alkyl and Aryl Transferases; Animals; Anti-Arrhythmia Agents; Antioxidants; Aspartic Acid Endopeptid

2007
[Effect of berberine on left ventricular remodeling in renovascular hypertensive rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:3

    Topics: Animals; Berberine; Collagen; Cyclic AMP; Cyclic GMP; Hypertension, Renovascular; Male; Myocardium;

2007