Page last updated: 2024-10-23

berberine and Cancer of Prostate

berberine has been researched along with Cancer of Prostate in 13 studies

Research Excerpts

ExcerptRelevanceReference
"Berberine has displayed significant anti-prostate cancer activities."5.40Mitochondrial protein cyclophilin-D-mediated programmed necrosis attributes to berberine-induced cytotoxicity in cultured prostate cancer cells. ( Gao, XH; Guo, F; Wu, YL; Zhang, LY, 2014)
"Berberine (Brb) is an active isoquinoline alkaloid occurring in various common plant species, with well-known potential for cancer therapy."1.51Anionic and Cationic Vitamin E-TPGS Mixed Polymeric Phospholipid Micellar Vehicles. ( Elbayoumi, T; Yao, M, 2019)
"Berberine is a well‑known component of the Chinese herbal medicine Huanglian (Coptis chinensis), and is capable of inhibiting the proliferation of multiple cancer cell lines."1.42Berberine targets epidermal growth factor receptor signaling to suppress prostate cancer proliferation in vitro. ( Huang, ZH; Li, QX; Wang, WL; Wang, Y; Wu, JL; Zheng, HF; Zhong, LF, 2015)
"Berberine is a natural alkaloid with significant antitumor activities against many types of cancer cells."1.42Berberine inhibits the metastatic ability of prostate cancer cells by suppressing epithelial-to-mesenchymal transition (EMT)-associated genes with predictive and prognostic relevance. ( Huang, CC; Lai, IL; Lee, KH; Liu, CH; Sia, P; Tang, WC; Wu, MH; Yang, PM, 2015)
"Berberine is a quaternary ammonium salt that is extracted from plants."1.42Berberine inhibits the proliferation of prostate cancer cells and induces G₀/G₁ or G₂/M phase arrest at different concentrations. ( Du, S; Lu, W; Wang, J, 2015)
"Berberine may inhibit the expression of HIF-1α and VEGF and thus confer radiosensitivity on prostatic cancer cells."1.40Berberine inhibits the expression of hypoxia induction factor-1alpha and increases the radiosensitivity of prostate cancer. ( Cai, J; Dai, S; Huang, G; Kang, Y; Li, D; Ma, J; Ma, Z; Mao, W; Sun, X; Tao, G; Wang, J; Wang, Z; Yang, B; Yang, X; Zhang, C; Zhang, Q, 2014)
"Berberine has displayed significant anti-prostate cancer activities."1.40Mitochondrial protein cyclophilin-D-mediated programmed necrosis attributes to berberine-induced cytotoxicity in cultured prostate cancer cells. ( Gao, XH; Guo, F; Wu, YL; Zhang, LY, 2014)
"Berberine has been shown to possess anti-tumor activity against a wide spectrum of cancer cells."1.38Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells. ( Gong, Y; Li, B; Liu, Q; Liu, Z; Shao, C; Sun, Z; Wang, Y; Zhang, X; Zhou, H, 2012)
"Berberine treatment inhibited cell cancer growth in a concentration (0-50 microM) and time- (0-48 h) dependent manner without any growth inhibition in normal human prostate epithelial PWR-1E cells."1.35Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells. ( Choi, MS; Han, SB; Hong, JT; Jung, HY; Kim, SM; Lee, YM; Moon, DC; Oh, JH; Yoo, HS, 2009)
"The treatment of human prostate cancer cells (PC-3) with berberine induced dose-dependent apoptosis but this effect of berberine was not seen in non-neoplastic human prostate epithelial cells (PWR-1E)."1.35Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation. ( Katiyar, S; Katiyar, SK; Meeran, SM, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's8 (61.54)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Berlin, IG1
Jennings, CC1
Shin, S1
Kenealey, J1
Yao, M1
Elbayoumi, T1
Zhang, Q1
Zhang, C1
Yang, X1
Yang, B1
Wang, J2
Kang, Y1
Wang, Z1
Li, D1
Huang, G1
Ma, Z1
Sun, X1
Cai, J1
Tao, G1
Dai, S1
Mao, W1
Ma, J1
Zhang, LY1
Wu, YL1
Gao, XH1
Guo, F1
Huang, ZH1
Zheng, HF1
Wang, WL1
Wang, Y2
Zhong, LF1
Wu, JL1
Li, QX1
Liu, CH1
Tang, WC1
Sia, P1
Huang, CC1
Yang, PM1
Wu, MH1
Lai, IL1
Lee, KH1
Lu, W1
Du, S1
Muralimanoharan, SB1
Kunnumakkara, AB1
Shylesh, B1
Kulkarni, KH1
Haiyan, X1
Ming, H1
Aggarwal, BB1
Rita, G1
Kumar, AP1
Choi, MS1
Oh, JH1
Kim, SM1
Jung, HY1
Yoo, HS1
Lee, YM1
Moon, DC1
Han, SB1
Hong, JT1
Li, J1
Cao, B1
Liu, X1
Fu, X1
Xiong, Z1
Chen, L1
Sartor, O1
Dong, Y1
Zhang, H1
Liu, Q1
Liu, Z1
Li, B1
Sun, Z1
Zhou, H1
Zhang, X1
Gong, Y1
Shao, C1
Mantena, SK1
Sharma, SD1
Katiyar, SK2
Meeran, SM1
Katiyar, S1

Other Studies

13 other studies available for berberine and Cancer of Prostate

ArticleYear
Utilizing mixture design response surface methodology to determine effective combinations of plant derived compounds as prostate cancer treatments.
    Cancer reports (Hoboken, N.J.), 2023, Volume: 6, Issue:4

    Topics: Androgens; Berberine; Cell Line, Tumor; Docetaxel; Emodin; Humans; Male; Phytochemicals; Prostatic N

2023
Anionic and Cationic Vitamin E-TPGS Mixed Polymeric Phospholipid Micellar Vehicles.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 2000

    Topics: Antineoplastic Agents; Berberine; Cell Line, Tumor; Drug Delivery Systems; Humans; Hydrophobic and H

2019
Berberine inhibits the expression of hypoxia induction factor-1alpha and increases the radiosensitivity of prostate cancer.
    Diagnostic pathology, 2014, May-27, Volume: 9

    Topics: Animals; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Dru

2014
Mitochondrial protein cyclophilin-D-mediated programmed necrosis attributes to berberine-induced cytotoxicity in cultured prostate cancer cells.
    Biochemical and biophysical research communications, 2014, Jul-18, Volume: 450, Issue:1

    Topics: Berberine; Cell Line, Tumor; Cell Survival; Cyclophilins; Humans; Male; Mitochondrial Proteins; Necr

2014
Berberine targets epidermal growth factor receptor signaling to suppress prostate cancer proliferation in vitro.
    Molecular medicine reports, 2015, Volume: 11, Issue:3

    Topics: Apoptosis; Berberine; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell

2015
Berberine inhibits the metastatic ability of prostate cancer cells by suppressing epithelial-to-mesenchymal transition (EMT)-associated genes with predictive and prognostic relevance.
    International journal of medical sciences, 2015, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Biomarkers, Tumor; Bone Morphogenetic Protein 7; Cell

2015
Berberine inhibits the proliferation of prostate cancer cells and induces G₀/G₁ or G₂/M phase arrest at different concentrations.
    Molecular medicine reports, 2015, Volume: 11, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell

2015
Butanol fraction containing berberine or related compound from nexrutine inhibits NFkappaB signaling and induces apoptosis in prostate cancer cells.
    The Prostate, 2009, Apr-01, Volume: 69, Issue:5

    Topics: Adenocarcinoma; Apoptosis; Berberine; Butanols; Cell Line, Tumor; Cell Proliferation; Humans; I-kapp

2009
Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells.
    International journal of oncology, 2009, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Berberine; Cell Cycle; Cell Proliferation; Cells, Cultured; Down-Regulation; Hum

2009
Berberine suppresses androgen receptor signaling in prostate cancer.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Cell Line, Tumor; Cell Nucleus; Cell Prolifera

2011
Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells.
    Mutation research, 2012, Jun-01, Volume: 734, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Cell Cycle Checkpoints; Cell Division; Cell Li

2012
Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:2

    Topics: Androgens; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Carcinoma; Caspase 3; Caspase In

2006
Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation.
    Toxicology and applied pharmacology, 2008, May-15, Volume: 229, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Berberine; Caspase 3; C

2008