berberine has been researched along with Brain Neoplasms in 14 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was aimed to investigate the effect of berberine on cell migration and invasion in human retinoblastoma (Rb) cells." | 7.88 | Inhibition of migration and invasion by berberine via inactivation of PI3K/Akt and p38 in human retinoblastoma cell line. ( Chen, K; Gong, Y; Gui, M; Guo, X; Jin, Y; Ma, R; Wang, P; Wang, X; Wang, Y; Wu, Y; Yang, L; Yuan, J; Zhong, Y, 2018) |
| "Berberine is a protoberberine alkaloid with wide range of pharmacological activities, applicable to various pathological conditions." | 6.72 | Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms. ( Asemi, Z; Behnam, M; Mirzaei, H; Pourattar, MA; Razavi, ZS; Tamtaji, OR, 2021) |
| "Berberine (BBR) is an isoquinoline quaternary alkaloid extracted from a variety of medicinal plants." | 6.66 | Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression. ( Bruno, G; Calvani, M; Favre, C; Subbiani, A, 2020) |
| "Chemotherapy is a conventional treatment for glioma, but its efficacy is greatly limited due to low blood-brain barrier (BBB) permeability and lack of specificity." | 5.72 | Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma. ( Chen, J; Hai, L; Liu, Q; Lu, R; Wang, S; Wu, Y; Yang, C; Yang, Z, 2022) |
| "Berberine (BBR) was the potential drug for anti-tumor in glioma cells." | 5.56 | Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway. ( An, J; Dong, W; He, Y; Jia, X; Jia, Y; Liu, K; Ma, X; Pan, Y; Sheng, J; Wang, B; Wang, J; Wang, S; Wang, X; Wu, Y; Yu, D; Yu, W; Zhao, Y; Zhu, W, 2020) |
| " However, use of a formulation of curcumin with higher bioavailability or combining it with berberine as a co-treatment may be proving to be more efficacious against cancer." | 5.51 | Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments. ( Dunbar, GL; Maiti, P; Plemmons, A, 2019) |
| "Berberine treatment of T98G cell lines inhibited cell proliferation and induced cell death in a dose (50-200 microg/ml) dependent manner with an IC50 value of 134 microg/ml, which was associated with an increase in G1 arrest." | 5.35 | Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway. ( Eom, KS; Hong, JM; Kim, JM; Kim, TY; Park, R; So, HS; Youn, MJ, 2008) |
| "This study was aimed to investigate the effect of berberine on cell migration and invasion in human retinoblastoma (Rb) cells." | 3.88 | Inhibition of migration and invasion by berberine via inactivation of PI3K/Akt and p38 in human retinoblastoma cell line. ( Chen, K; Gong, Y; Gui, M; Guo, X; Jin, Y; Ma, R; Wang, P; Wang, X; Wang, Y; Wu, Y; Yang, L; Yuan, J; Zhong, Y, 2018) |
| "Berberine is a protoberberine alkaloid with wide range of pharmacological activities, applicable to various pathological conditions." | 2.72 | Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms. ( Asemi, Z; Behnam, M; Mirzaei, H; Pourattar, MA; Razavi, ZS; Tamtaji, OR, 2021) |
| "Berberine (BBR) is an isoquinoline quaternary alkaloid extracted from a variety of medicinal plants." | 2.66 | Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression. ( Bruno, G; Calvani, M; Favre, C; Subbiani, A, 2020) |
| "Chemotherapy is a conventional treatment for glioma, but its efficacy is greatly limited due to low blood-brain barrier (BBB) permeability and lack of specificity." | 1.72 | Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma. ( Chen, J; Hai, L; Liu, Q; Lu, R; Wang, S; Wu, Y; Yang, C; Yang, Z, 2022) |
| "Berberine (BBR) was the potential drug for anti-tumor in glioma cells." | 1.56 | Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway. ( An, J; Dong, W; He, Y; Jia, X; Jia, Y; Liu, K; Ma, X; Pan, Y; Sheng, J; Wang, B; Wang, J; Wang, S; Wang, X; Wu, Y; Yu, D; Yu, W; Zhao, Y; Zhu, W, 2020) |
| " However, use of a formulation of curcumin with higher bioavailability or combining it with berberine as a co-treatment may be proving to be more efficacious against cancer." | 1.51 | Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments. ( Dunbar, GL; Maiti, P; Plemmons, A, 2019) |
| "Berberine treatment of T98G cell lines inhibited cell proliferation and induced cell death in a dose (50-200 microg/ml) dependent manner with an IC50 value of 134 microg/ml, which was associated with an increase in G1 arrest." | 1.35 | Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway. ( Eom, KS; Hong, JM; Kim, JM; Kim, TY; Park, R; So, HS; Youn, MJ, 2008) |
| "The cell-killing effect and its possible mechanism of berberine used alone or in combination with argon ion laser treatment on 9L rat glioma cells were studied." | 1.29 | Effect of berberine alone or in combination with argon ion laser treatment on 9L rat glioma cell line. ( Chen, KT; Chen, YC; Hao, DM; Liu, ZX; You, ZS, 1994) |
| "Berberine was evaluated for antitumor activity against malignant brain tumors." | 1.28 | Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors. ( Dougherty, DV; Rosenblum, ML; Zhang, RX, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Bibak, B | 1 |
| Shakeri, F | 1 |
| Keshavarzi, Z | 1 |
| Mollazadeh, H | 1 |
| Javid, H | 1 |
| Jalili-Nik, M | 1 |
| Sathyapalan, T | 1 |
| Afshari, AR | 1 |
| Sahebkar, A | 1 |
| Yang, C | 1 |
| Yang, Z | 1 |
| Wang, S | 2 |
| Chen, J | 1 |
| Liu, Q | 1 |
| Hai, L | 1 |
| Lu, R | 1 |
| Wu, Y | 3 |
| Maiti, P | 1 |
| Plemmons, A | 1 |
| Dunbar, GL | 1 |
| Asemi, Z | 1 |
| Behnam, M | 1 |
| Pourattar, MA | 1 |
| Mirzaei, H | 1 |
| Razavi, ZS | 1 |
| Tamtaji, OR | 1 |
| Calvani, M | 1 |
| Subbiani, A | 1 |
| Bruno, G | 1 |
| Favre, C | 1 |
| An, J | 1 |
| Dong, W | 1 |
| Wang, X | 2 |
| Sheng, J | 1 |
| Jia, Y | 1 |
| He, Y | 2 |
| Ma, X | 1 |
| Wang, J | 1 |
| Yu, D | 1 |
| Jia, X | 1 |
| Wang, B | 1 |
| Yu, W | 1 |
| Liu, K | 1 |
| Zhao, Y | 1 |
| Zhu, W | 1 |
| Pan, Y | 1 |
| Sun, Y | 1 |
| Yu, J | 1 |
| Liu, X | 2 |
| Zhang, C | 1 |
| Cao, J | 1 |
| Li, G | 1 |
| Chen, Y | 1 |
| Huang, H | 1 |
| Wang, Y | 1 |
| Yuan, J | 1 |
| Yang, L | 1 |
| Wang, P | 1 |
| Chen, K | 1 |
| Ma, R | 1 |
| Zhong, Y | 1 |
| Guo, X | 1 |
| Gong, Y | 1 |
| Gui, M | 1 |
| Jin, Y | 1 |
| Wang, DY | 1 |
| Yeh, CC | 1 |
| Lee, JH | 1 |
| Hung, CF | 1 |
| Chung, JG | 1 |
| Liu, SJ | 1 |
| Sun, YM | 1 |
| Tian, DF | 1 |
| He, YC | 1 |
| Zeng, L | 1 |
| Ling, CQ | 1 |
| Sun, SH | 1 |
| Eom, KS | 1 |
| Hong, JM | 1 |
| Youn, MJ | 1 |
| So, HS | 1 |
| Park, R | 1 |
| Kim, JM | 1 |
| Kim, TY | 1 |
| Chen, KT | 1 |
| Hao, DM | 1 |
| Liu, ZX | 1 |
| Chen, YC | 1 |
| You, ZS | 1 |
| Iwasa, K | 1 |
| Moriyasu, M | 1 |
| Yamori, T | 1 |
| Turuo, T | 1 |
| Lee, DU | 1 |
| Wiegrebe, W | 1 |
| Zhang, RX | 1 |
| Dougherty, DV | 1 |
| Rosenblum, ML | 1 |
3 reviews available for berberine and Brain Neoplasms
| Article | Year |
|---|---|
Anticancer Mechanisms of Berberine: A Good Choice for Glioblastoma Multiforme Therapy.
Topics: Apoptosis; Berberine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans | 2022 |
Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Berberine; Brain Neoplasms; Cell Proliferatio | 2021 |
Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression.
Topics: Adrenergic beta-Antagonists; Animals; Berberine; Brain Neoplasms; Cell Proliferation; Dietary Supple | 2020 |
11 other studies available for berberine and Brain Neoplasms
| Article | Year |
|---|---|
Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma.
Topics: Berberine; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Glioma; Humans; Hyd | 2022 |
Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Berberine; Biological Availability; Brain | 2019 |
Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Biological Transport; Blood-Brain Barrier; Bra | 2020 |
Oncosis-like cell death is induced by berberine through ERK1/2-mediated impairment of mitochondrial aerobic respiration in gliomas.
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Apoptosis; Autophagy; Berberine; Brain Neoplasms; Cell | 2018 |
Inhibition of migration and invasion by berberine via inactivation of PI3K/Akt and p38 in human retinoblastoma cell line.
Topics: Berberine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Huma | 2018 |
Berberine inhibited arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells.
Topics: Arylamine N-Acetyltransferase; Astrocytoma; Base Sequence; Berberine; Brain Neoplasms; DNA Adducts; | 2002 |
Downregulated NM23-H1 expression is associated with intracranial invasion of nasopharyngeal carcinoma.
Topics: Adult; Animals; Antineoplastic Agents; Berberine; Brain Neoplasms; Carcinoma; Down-Regulation; Drug | 2008 |
Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway.
Topics: Apoptosis; Berberine; Blotting, Western; Brain Neoplasms; Caspases; Cell Cycle; Cell Cycle Proteins; | 2008 |
Effect of berberine alone or in combination with argon ion laser treatment on 9L rat glioma cell line.
Topics: Animals; Antineoplastic Agents; Berberine; Brain Neoplasms; Cell Survival; Gliosarcoma; Laser Therap | 1994 |
In vitro cytotoxicity of the protoberberine-type alkaloids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast | 2001 |
Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine; Brain Neo | 1990 |