Page last updated: 2024-10-23

berberine and B16 Melanoma

berberine has been researched along with B16 Melanoma in 11 studies

Research Excerpts

ExcerptRelevanceReference
"Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on melanoma cells, including inhibiting cancer viability, blocking cell cycle and migration."7.83Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells. ( Du, B; Kou, Y; Li, B; Li, H; Li, L; Tan, Y; Wang, K, 2016)
"Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on melanoma cells, including inhibiting cancer viability, blocking cell cycle and migration."3.83Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells. ( Du, B; Kou, Y; Li, B; Li, H; Li, L; Tan, Y; Wang, K, 2016)
"Berberine has abundant beneficial properties including anti-cancer effects."1.48Inhibitory effect of berberine from ( Lee, Y; Liu, L; Yi, Y, 2018)
"Berberine treatment also decreased various biochemical parameters associated with lung metastasis."1.38Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells. ( Hamsa, TP; Kuttan, G, 2012)
"Berberine- and AICAR-treated groups demonstrated significantly decreased lung metastases in the pulmonary metastasis model in vivo."1.38Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. ( Kim, EJ; Kim, HS; Kim, MJ; Lee, MS; Lim, JS; Yang, Y, 2012)
"Berberine could also inhibit endothelial motility, migration, tube formation, and vessel sprouting from rat aortic ring in vitro."1.38Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators. ( Hamsa, TP; Kuttan, G, 2012)
"Berberine displays multiphasic effects in these malignant cell lines, which are correlated with the concentration and intracellular distribution of this alkaloid."1.35Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. ( Holy, J; Oliveira, PJ; Parke, D; Perkins, E; Sardao, VA; Serafim, TL, 2008)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Lin, H1
Lin, L1
Choi, Y1
Michniak-Kohn, B1
Lee, Y2
Liu, L1
Yi, Y1
Song, YC1
Kim, HM1
Hyun, MY1
Lim, YY1
Song, KY1
Kim, BJ1
Kou, Y1
Li, L1
Li, H1
Tan, Y1
Li, B1
Wang, K1
Du, B1
Hamsa, TP2
Kuttan, G2
Kim, HS1
Kim, MJ1
Kim, EJ1
Yang, Y1
Lee, MS1
Lim, JS1
Letasiová, S1
Jantová, S1
Múcková, M1
Theiszová, M1
Tanabe, H1
Suzuki, H1
Nagatsu, A1
Mizukami, H1
Ogihara, Y1
Inoue, M1
Serafim, TL2
Oliveira, PJ2
Sardao, VA2
Perkins, E1
Parke, D2
Holy, J2
Pereira, GC1
Branco, AF1
Matos, JA1
Pereira, SL1
Perkins, EL1
Santos, MS1
Moreno, AJ1

Other Studies

11 other studies available for berberine and B16 Melanoma

ArticleYear
Development and in-vitro evaluation of co-loaded berberine chloride and evodiamine ethosomes for treatment of melanoma.
    International journal of pharmaceutics, 2020, May-15, Volume: 581

    Topics: Animals; Berberine; Drug Delivery Systems; Drug Development; Female; Humans; Liposomes; Melanoma, Ex

2020
Inhibitory effect of berberine from
    Die Pharmazie, 2018, 05-01, Volume: 73, Issue:5

    Topics: alpha-MSH; Animals; Berberine; Cell Line, Tumor; Coptis chinensis; Dose-Response Relationship, Drug;

2018
Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells.
    International journal of molecular medicine, 2015, Volume: 35, Issue:4

    Topics: Animals; Berberine; Cell Line, Tumor; Cell Survival; Enzyme Activation; Extracellular Signal-Regulat

2015
Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells.
    Biochemical and biophysical research communications, 2016, Oct-14, Volume: 479, Issue:2

    Topics: Animals; Antineoplastic Agents; Berberine; Chromones; Epithelial-Mesenchymal Transition; Gene Expres

2016
Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:4

    Topics: Activating Transcription Factor 2; Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line,

2012
Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression.
    Biochemical pharmacology, 2012, Feb-01, Volume: 83, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Berberine; Cell Line, Tumor; Cyclooxygenase 2; Enzyme Activa

2012
Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators.
    Drug and chemical toxicology, 2012, Volume: 35, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Berberine; Cell Line, Tumor; Down-Regulation; Gene Expression Regu

2012
Antiproliferative activity of berberine in vitro and in vivo.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2005, Volume: 149, Issue:2

    Topics: Animals; Antineoplastic Agents; Berberine; Cell Proliferation; Drug Screening Assays, Antitumor; In

2005
Selective inhibition of vascular smooth muscle cell proliferation by coptisine isolated from Coptis rhizoma, one of the crude drugs composing Kampo medicines Unsei-in.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2006, Volume: 13, Issue:5

    Topics: Animals; Berberine; Cell Cycle; Cell Proliferation; Chromatography, High Pressure Liquid; Coptis; Dr

2006
Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:6

    Topics: Animals; Antimetabolites; Berberine; Bromodeoxyuridine; Carbonyl Cyanide p-Trifluoromethoxyphenylhyd

2008
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Berberine; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhyd

2007