Page last updated: 2024-10-23

berberine and Autoimmune Diabetes

berberine has been researched along with Autoimmune Diabetes in 8 studies

Research Excerpts

ExcerptRelevanceReference
"Latent autoimmune diabetes in adults (LADA) is a heterogeneous form of diabetes, characterized by autoimmune destruction of pancreatic β-cells as well as insulin resistance and is triggered by environmental factors in the context of genetic susceptibility."7.11Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial. ( Mei, Z; Wu, X; Xiao, Y; Yan, J; Yang, W; Zhang, R; Zhou, Z, 2022)
"In animal models, treatment of type 2 diabetes mellitus rats with BBR lowered fasting blood glucose and fasting serum insulin, increased insulin sensitivity, and elevated InsR mRNA as well as PKC activity in the liver."5.35Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. ( Jiang, JD; Kong, WJ; Li, ZR; Pan, HN; Shan, N; Si, SY; Song, DQ; Wang, YM; Wei, J; Xue, R; Yang, P; You, XF; Zhang, H; Zhao, LX; Zhao, W; Zhou, ZX, 2009)
"Latent autoimmune diabetes in adults (LADA) is a heterogeneous form of diabetes, characterized by autoimmune destruction of pancreatic β-cells as well as insulin resistance and is triggered by environmental factors in the context of genetic susceptibility."3.11Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial. ( Mei, Z; Wu, X; Xiao, Y; Yan, J; Yang, W; Zhang, R; Zhou, Z, 2022)
"Berberine (BBR) can ameliorate type 2 diabetes and insulin resistance in many ways."1.91Berberine Regulates GPX4 to Inhibit Ferroptosis of Islet β Cells. ( Bao, L; Han, J; Jin, Y; Qian, L; Wang, W; Wu, W, 2023)
"Berberine is a compound for which both antidiabetic and antiosteoporotic effects have been documented."1.72Lack of berberine effect on bone mechanical properties in rats with experimentally induced diabetes. ( Cegieła, U; Folwarczna, J; Gajdoš, M; Janas, A; Kisiel-Nawrot, E; Kocik, S; Krivošíková, Z; Londzin, P; Skoczyńska, A; Štefíková, K, 2022)
"In animal models, treatment of type 2 diabetes mellitus rats with BBR lowered fasting blood glucose and fasting serum insulin, increased insulin sensitivity, and elevated InsR mRNA as well as PKC activity in the liver."1.35Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. ( Jiang, JD; Kong, WJ; Li, ZR; Pan, HN; Shan, N; Si, SY; Song, DQ; Wang, YM; Wei, J; Xue, R; Yang, P; You, XF; Zhang, H; Zhao, LX; Zhao, W; Zhou, ZX, 2009)
"Because type 1 diabetes is caused by T cell-mediated destruction of beta cells and severe islet inflammation, we hypothesized that berberine could ameliorate type 1 diabetes through its immune regulation properties."1.35Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice. ( Cui, G; Ge, B; Gong, Z; Qin, X; Zang, YQ; Zhang, Y, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Londzin, P1
Kocik, S1
Kisiel-Nawrot, E1
Janas, A1
Skoczyńska, A1
Krivošíková, Z1
Štefíková, K1
Gajdoš, M1
Cegieła, U1
Folwarczna, J1
Zhang, R1
Xiao, Y1
Yan, J1
Yang, W1
Wu, X1
Mei, Z1
Zhou, Z1
Bao, L1
Jin, Y1
Han, J1
Wang, W1
Qian, L1
Wu, W1
Sun, J1
Bao, H1
Peng, Y1
Zhang, H3
Sun, Y1
Qi, J1
Gao, Y1
Kong, WJ1
Song, DQ1
Xue, R1
Zhao, W1
Wei, J1
Wang, YM1
Shan, N1
Zhou, ZX1
Yang, P1
You, XF1
Li, ZR1
Si, SY1
Zhao, LX1
Pan, HN1
Jiang, JD1
Cui, G1
Qin, X1
Zhang, Y1
Gong, Z1
Ge, B1
Zang, YQ1
Chueh, WH2
Lin, JY2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: A Randomized Controlled Trial[NCT04698330]Phase 4240 participants (Anticipated)Interventional2022-05-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for berberine and Autoimmune Diabetes

ArticleYear
Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adult; Berberine; Diabetes Mellitus, Type 1; Glucose Intolerance; Humans; Insulin; Inulin; Latent Au

2022

Other Studies

7 other studies available for berberine and Autoimmune Diabetes

ArticleYear
Lack of berberine effect on bone mechanical properties in rats with experimentally induced diabetes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 146

    Topics: Animals; Berberine; Bone Density; Bone Remodeling; Diabetes Mellitus, Experimental; Diabetes Mellitu

2022
Berberine Regulates GPX4 to Inhibit Ferroptosis of Islet β Cells.
    Planta medica, 2023, Volume: 89, Issue:3

    Topics: Berberine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ferroptosis; Reactive Oxygen Specie

2023
Improvement of intestinal transport, absorption and anti-diabetic efficacy of berberine by using Gelucire44/14: In vitro, in situ and in vivo studies.
    International journal of pharmaceutics, 2018, Jun-10, Volume: 544, Issue:1

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; B

2018
Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:1

    Topics: Animals; Berberine; Cell Line, Tumor; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female;

2009
Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice.
    The Journal of biological chemistry, 2009, Oct-09, Volume: 284, Issue:41

    Topics: Animals; Berberine; Cell Differentiation; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Anim

2009
Berberine, an isoquinoline alkaloid in herbal plants, protects pancreatic islets and serum lipids in nonobese diabetic mice.
    Journal of agricultural and food chemistry, 2011, Jul-27, Volume: 59, Issue:14

    Topics: Animals; Berberine; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 1; Disease Models, A

2011
Protective effect of berberine on serum glucose levels in non-obese diabetic mice.
    International immunopharmacology, 2012, Volume: 12, Issue:3

    Topics: Animals; Berberine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Energy Intake; Female; Gl

2012