Page last updated: 2024-10-23

berberine and Atherogenesis

berberine has been researched along with Atherogenesis in 34 studies

Research Excerpts

ExcerptRelevanceReference
"We conducted a meta-analysis to evaluate the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS), explore its anti-inflammatory effects, and assess its potential applications for AIS patients."9.41Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis. ( Chen, B; Harkare, HV; Huang, B; Luo, D; Ma, T; Pan, J; Shi, S; Song, Y; Sun, S; Wang, L; Yu, B, 2023)
"Atherosclerosis is the primary cause of many cardiovascular diseases, and an increasing number of studies have shown that berberine could delay plaque formation and development."9.22Efficacy and Underlying Mechanism of Berberine Against Atherosclerosis: A Meta-Analysis in Preclinical Animal Studies. ( Guo, Q; Jia, D; Liu, M; Shi, L; Wu, A; Yang, R; Yu, H; Zhang, D; Zhang, X; Zhao, M, 2022)
" Berberine is the main alkaloid of Coptis Chinensis, and, recent researches showed that berberine had the effect of anti-atherosclerosis."8.86Advance of studies on anti-atherosclerosis mechanism of berberine. ( Liu, LT; Wang, J; Wu, M, 2010)
"Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis."8.02Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021)
"Berberine (BBR) is an effective component of Huanglian and has shown to attenuate atherosclerosis (AS); however, the detailed mechanism of BBR-mediated protective actions against AS remains elusive."7.96Berberine Attenuates Arterial Plaque Formation in Atherosclerotic Rats with Damp-Heat Syndrome via Regulating Autophagy. ( Huang, Y; Ke, X; Li, L; Lin, F; Song, Y; Xin, F; Xu, L; Zeng, Z; Zhang, Y, 2020)
"Berberine (BBR) has long been used for treating bacterial diarrhea due to its antimicrobial effect and is currently used to treat obesity, diabetes, hyperlipemia and atherosclerosis."7.88Berberine treatment reduces atherosclerosis by mediating gut microbiota in apoE-/- mice. ( Geng, J; Hu, J; Hu, T; Jiang, Y; Li, J; Liu, S; Shi, Y; Wang, B; Yan, W, 2018)
"Berberine (BBR) possesses significant anti-atherosclerosis properties."7.88Suppressive effects of berberine on atherosclerosis via downregulating visfatin expression and attenuating visfatin-induced endothelial dysfunction. ( Cui, X; Liu, Z; Wan, Q; Yang, Y, 2018)
" Berberine is used to treat obesity, diabetes and atherosclerosis."7.88Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe ( Dong, L; Hu, Y; Liu, T; Shen, X; Weng, S; Zhang, D; Zhu, H; Zhu, J; Zhu, L, 2018)
"Berberine can counteract HFD-elicited hyperhomocysteinemia and hyperlipidemia partially via upregulating LDLR and apoE mRNA levels and suppressing HMGR gene expression."7.78The effects of berberine on hyperhomocysteinemia and hyperlipidemia in rats fed with a long-term high-fat diet. ( Bian, H; Chang, XX; Gao, X; Xia, MF; Xu, Q; Yan, HM; Zhu, TF, 2012)
"We conclude that berberine reduces oxidative stress and vascular inflammation, and suppresses atherogenesis via a mechanism that includes stimulation of AMPK-dependent UCP2 expression."7.77Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. ( Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH, 2011)
"Berberine is a natural isoquinoline alkaloid extracted from Coptis chinensis that has a wide range of pharmacological effects."6.53The Role of Berberine in the Multi-Target Treatment of Senile Dementia. ( Chen, S; Guo, Y; Huang, M; Liang, Y, 2016)
"Diabetic atherosclerosis is characterized by hyperglycemia, hyperinsulinemia, and dyslipidemia."5.72Berberine attenuates diabetic atherosclerosis via enhancing the interplay between KLF16 and PPARα in ApoE ( Hu, C; Ma, C; Man, B; Xiang, J; Yang, G; Yang, S, 2022)
" It has been reported that 8-cetylberberine (8-BBR-C16) has increased anti-microbial property in vivo and a higher bioavailability in hamsters."5.46Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE ( Feng, M; Hu, Y; Li, X; Ma, H; Xiao, Y; Ye, X; Zhou, X; Zou, Z, 2017)
"We conducted a meta-analysis to evaluate the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS), explore its anti-inflammatory effects, and assess its potential applications for AIS patients."5.41Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis. ( Chen, B; Harkare, HV; Huang, B; Luo, D; Ma, T; Pan, J; Shi, S; Song, Y; Sun, S; Wang, L; Yu, B, 2023)
"Atherosclerosis is the primary cause of many cardiovascular diseases, and an increasing number of studies have shown that berberine could delay plaque formation and development."5.22Efficacy and Underlying Mechanism of Berberine Against Atherosclerosis: A Meta-Analysis in Preclinical Animal Studies. ( Guo, Q; Jia, D; Liu, M; Shi, L; Wu, A; Yang, R; Yu, H; Zhang, D; Zhang, X; Zhao, M, 2022)
" Berberine has been used to treat obesity, diabetes mellitus, atherosclerosis, and metabolic diseases in China."5.05Effects of Berberine on the Gastrointestinal Microbiota. ( Chen, F; Liao, Y; Sun, X; Wang, L; Wu, X; Wu, Z; Yang, R; Zhang, L; Zhu, Z, 2020)
" Berberine is the main alkaloid of Coptis Chinensis, and, recent researches showed that berberine had the effect of anti-atherosclerosis."4.86Advance of studies on anti-atherosclerosis mechanism of berberine. ( Liu, LT; Wang, J; Wu, M, 2010)
"Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis."4.02Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021)
"Berberine (BBR) is an effective component of Huanglian and has shown to attenuate atherosclerosis (AS); however, the detailed mechanism of BBR-mediated protective actions against AS remains elusive."3.96Berberine Attenuates Arterial Plaque Formation in Atherosclerotic Rats with Damp-Heat Syndrome via Regulating Autophagy. ( Huang, Y; Ke, X; Li, L; Lin, F; Song, Y; Xin, F; Xu, L; Zeng, Z; Zhang, Y, 2020)
"Berberine (BBR) possesses significant anti-atherosclerosis properties."3.88Suppressive effects of berberine on atherosclerosis via downregulating visfatin expression and attenuating visfatin-induced endothelial dysfunction. ( Cui, X; Liu, Z; Wan, Q; Yang, Y, 2018)
"Berberine (BBR) has long been used for treating bacterial diarrhea due to its antimicrobial effect and is currently used to treat obesity, diabetes, hyperlipemia and atherosclerosis."3.88Berberine treatment reduces atherosclerosis by mediating gut microbiota in apoE-/- mice. ( Geng, J; Hu, J; Hu, T; Jiang, Y; Li, J; Liu, S; Shi, Y; Wang, B; Yan, W, 2018)
" Berberine is used to treat obesity, diabetes and atherosclerosis."3.88Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe ( Dong, L; Hu, Y; Liu, T; Shen, X; Weng, S; Zhang, D; Zhu, H; Zhu, J; Zhu, L, 2018)
"Berberine can counteract HFD-elicited hyperhomocysteinemia and hyperlipidemia partially via upregulating LDLR and apoE mRNA levels and suppressing HMGR gene expression."3.78The effects of berberine on hyperhomocysteinemia and hyperlipidemia in rats fed with a long-term high-fat diet. ( Bian, H; Chang, XX; Gao, X; Xia, MF; Xu, Q; Yan, HM; Zhu, TF, 2012)
"We conclude that berberine reduces oxidative stress and vascular inflammation, and suppresses atherogenesis via a mechanism that includes stimulation of AMPK-dependent UCP2 expression."3.77Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. ( Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH, 2011)
"Berberine is a bioactive isoquinoline alkaloid compound extracted from various medicinal plants, such as Barberry."2.82Modulatory effect of berberine on plasma lipoprotein (or lipid) profile: a review. ( Hashemy, SI; Nourizadeh, N; Saburi, E; Vazifeh Mostaan, L, 2022)
"Berberine is a natural isoquinoline alkaloid extracted from Coptis chinensis that has a wide range of pharmacological effects."2.53The Role of Berberine in the Multi-Target Treatment of Senile Dementia. ( Chen, S; Guo, Y; Huang, M; Liang, Y, 2016)
"Diabetic atherosclerosis is characterized by hyperglycemia, hyperinsulinemia, and dyslipidemia."1.72Berberine attenuates diabetic atherosclerosis via enhancing the interplay between KLF16 and PPARα in ApoE ( Hu, C; Ma, C; Man, B; Xiang, J; Yang, G; Yang, S, 2022)
"Atherosclerosis is a chronic inflammation condition resulting from the interaction between lipoproteins, monocyte-derived macrophages, T lymphocytes, and other cellular elements in the arterial wall."1.56Berberine Attenuates Cholesterol Accumulation in Macrophage Foam Cells by Suppressing AP-1 Activity and Activation of the Nrf2/HO-1 Pathway. ( Chen, Y; Ding, XS; Feng, N; Feng, XF; Liu, F; Yang, LC; Yang, XJ; Zhu, SX, 2020)
" It has been reported that 8-cetylberberine (8-BBR-C16) has increased anti-microbial property in vivo and a higher bioavailability in hamsters."1.46Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE ( Feng, M; Hu, Y; Li, X; Ma, H; Xiao, Y; Ye, X; Zhou, X; Zou, Z, 2017)
" Derivatives of BBR have been suggested to have enhanced bioavailability compared to BBR."1.40Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE(-/-) mice. ( Cao, J; Chen, J; Fang, L; Li, Y; Liu, B; Meng, S; Sun, Y; Wang, Y; Zhou, Q, 2014)
" In the present study, we aimed to investigate the effect of berberine combined with atorvastatin on LOX‑1 and explore the underlying molecular mechanism involved."1.40Berberine combined with atorvastatin downregulates LOX‑1 expression through the ET‑1 receptor in monocyte/macrophages. ( Chi, L; Hu, X; Pan, N; Peng, L; Zhang, Y, 2014)
"Berberine (BBR) is a botanical alkaloid that has been reported to have effects in cardiovascular diseases; however, the mechanisms involved are not yet fully understood."1.40The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1. ( Chi, L; Hu, X; Pan, N; Peng, L; Zhang, Y, 2014)
"Rats with renal artery stenosis were randomly assigned to two groups (n = 6 each) - ARD, or ARD+BBR - according to diet alone or in combination with BBR."1.39Berberine ameliorates chronic kidney injury caused by atherosclerotic renovascular disease through the suppression of NFκB signaling pathway in rats. ( Cao, CC; Chen, W; Chen, X; Huang, WJ; Liu, L; Miao, GG; Wan, X; Xie, HG; Zhang, Q; Zhao, Y, 2013)
"Berberine can inhibit the expression of LOX-1 and promote the expression of SR-BI in macrophage-derived foam cells."1.36Effects of berberine on expression of LOX-1 and SR-BI in human macrophage-derived foam cells induced by ox-LDL. ( Fang, X; Guan, J; Guan, S; Li, W; Wang, B, 2010)
"Berberine inhibits COX-2 expression via the ERK1/2 signalling pathway and, possibly, at a high dosage via the JNK pathway."1.35Biochemical pathways in the antiatherosclerotic effect of berberine. ( Guo, Y; Jiang, X; Li, FM; Wang, L; Wang, QZ; Zuo, YF, 2008)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (11.76)29.6817
2010's19 (55.88)24.3611
2020's11 (32.35)2.80

Authors

AuthorsStudies
Jia, D1
Zhang, X2
Guo, Q1
Yang, R2
Yu, H1
Zhao, M1
Shi, L1
Liu, M1
Wu, A1
Zhang, D2
Man, B1
Hu, C1
Yang, G1
Xiang, J1
Yang, S1
Ma, C1
Nourizadeh, N1
Vazifeh Mostaan, L1
Saburi, E1
Hashemy, SI1
Luo, D1
Yu, B1
Sun, S1
Chen, B1
Harkare, HV1
Wang, L6
Pan, J1
Huang, B1
Song, Y2
Ma, T1
Shi, S1
Yang, XJ1
Liu, F1
Feng, N1
Ding, XS1
Chen, Y1
Zhu, SX1
Yang, LC1
Feng, XF1
Tan, W1
Wang, Y3
Wang, K1
Wang, S1
Liu, J1
Qin, X1
Dai, Y1
Wang, X1
Gao, X2
Ke, X1
Huang, Y1
Li, L1
Xin, F1
Xu, L1
Zhang, Y5
Zeng, Z1
Lin, F1
Fatahian, A1
Haftcheshmeh, SM1
Azhdari, S1
Farshchi, HK1
Nikfar, B1
Momtazi-Borojeni, AA1
Deng, L1
Lin, N1
Shi, Y2
Chen, J2
Zhou, Y1
Chen, D1
Liu, S2
Li, C1
Zhang, L1
Wu, X1
Chen, F1
Liao, Y1
Zhu, Z1
Wu, Z1
Sun, X1
Li, X2
Su, C1
Jiang, Z1
Yang, Y2
Yang, M1
Du, Y1
Zhang, J1
Jiang, J1
Hong, B1
Zhu, L1
Zhu, H1
Zhu, J1
Weng, S1
Dong, L1
Liu, T1
Hu, Y2
Shen, X1
Wan, Q1
Liu, Z1
Cui, X1
Zhu, TL1
Yang, B1
Guo, YS1
Ji, YS1
Li, XY1
Geng, C1
Hidru, TH1
Zhi, L1
Tao, M1
Zou, L1
Chen, C1
Li, H1
Liu, Y2
Hu, J1
Geng, J1
Hu, T1
Wang, B2
Yan, W1
Jiang, Y1
Li, J1
Wan, X1
Chen, X1
Liu, L1
Zhao, Y1
Huang, WJ1
Zhang, Q1
Miao, GG1
Chen, W1
Xie, HG1
Cao, CC1
Chi, L2
Peng, L2
Hu, X2
Pan, N2
Zimetti, F1
Adorni, MP1
Ronda, N1
Gatti, R1
Bernini, F1
Favari, E1
Cao, J1
Fang, L1
Liu, B1
Zhou, Q1
Sun, Y1
Li, Y2
Meng, S2
Seo, CS1
Kim, OS1
Kim, JH1
Shin, HK1
Huang, M1
Chen, S1
Liang, Y1
Guo, Y2
Feng, M1
Zou, Z1
Zhou, X1
Ma, H1
Xiao, Y1
Ye, X1
Kou, JY1
Zhong, ZY1
Jiang, YQ1
Li, XS1
Han, XB1
Liu, ZN1
Tian, Y1
Yang, LM1
Wang, QZ1
Li, FM1
Jiang, X1
Zuo, YF1
Chen, FL1
Yang, ZH1
Li, LX1
Liang, WC1
Wang, XC1
Zhou, WB1
Yang, YH1
Hu, RM1
Wu, M2
Wang, J2
Li, K1
Yao, W1
Zheng, X1
Liao, K1
Huang, Z1
Chen, T1
Wang, C1
Liu, LT1
Guan, S1
Li, W1
Guan, J1
Fang, X1
Wang, Q1
Zhang, M1
Liang, B1
Shirwany, N1
Zhu, Y1
Zou, MH1
Chang, XX1
Yan, HM1
Xu, Q1
Xia, MF1
Bian, H1
Zhu, TF1

Reviews

9 reviews available for berberine and Atherogenesis

ArticleYear
Efficacy and Underlying Mechanism of Berberine Against Atherosclerosis: A Meta-Analysis in Preclinical Animal Studies.
    Journal of cardiovascular pharmacology, 2022, 09-01, Volume: 80, Issue:3

    Topics: Animals; Atherosclerosis; Berberine; Lipoproteins, HDL; Lipoproteins, LDL; Mice; Mice, Knockout, Apo

2022
Modulatory effect of berberine on plasma lipoprotein (or lipid) profile: a review.
    Molecular biology reports, 2022, Volume: 49, Issue:11

    Topics: Anti-Inflammatory Agents; Antioxidants; Aryldialkylphosphatase; Atherosclerosis; Berberine; Choleste

2022
Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:9

    Topics: Atherosclerosis; Berberine; Carotid Intima-Media Thickness; Humans; Ischemic Stroke; Stroke; Triglyc

2023
Promising Anti-atherosclerotic Effect of Berberine: Evidence from In Vitro, In Vivo, and Clinical Studies.
    Reviews of physiology, biochemistry and pharmacology, 2020, Volume: 178

    Topics: Atherosclerosis; Berberine; Cholesterol, LDL; Endothelial Cells; Humans; Receptors, LDL

2020
Effects of Berberine on the Gastrointestinal Microbiota.
    Frontiers in cellular and infection microbiology, 2020, Volume: 10

    Topics: Animals; Atherosclerosis; Berberine; China; Gastrointestinal Microbiome; Humans; Insulin Resistance

2020
Sonodynamic therapy: A potential treatment for atherosclerosis.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chal

2018
The Role of Berberine in the Multi-Target Treatment of Senile Dementia.
    Current topics in medicinal chemistry, 2016, Volume: 16, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Berberine; Cholinesterase Inhibit

2016
[Advance on study in anti-atherosclerosis mechanism of berberine].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:18

    Topics: Animals; Atherosclerosis; Berberine; Blood Glucose; Coptis; Drugs, Chinese Herbal; Humans; Myocytes,

2008
Advance of studies on anti-atherosclerosis mechanism of berberine.
    Chinese journal of integrative medicine, 2010, Volume: 16, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Berberine; Blood Glucose; Blood Pressure; Humans

2010

Other Studies

25 other studies available for berberine and Atherogenesis

ArticleYear
Berberine attenuates diabetic atherosclerosis via enhancing the interplay between KLF16 and PPARα in ApoE
    Biochemical and biophysical research communications, 2022, 10-08, Volume: 624

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Berberine; Diabetes Mellitus; Glucose; Inflammation; Kr

2022
Berberine Attenuates Cholesterol Accumulation in Macrophage Foam Cells by Suppressing AP-1 Activity and Activation of the Nrf2/HO-1 Pathway.
    Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:1

    Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subf

2020
Improvement of Endothelial Dysfunction of Berberine in Atherosclerotic Mice and Mechanism Exploring through TMT-Based Proteomics.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Berberine; Endothelium, Vascular; Fatty Acids; G

2020
Berberine Attenuates Arterial Plaque Formation in Atherosclerotic Rats with Damp-Heat Syndrome via Regulating Autophagy.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Administration, Oral; Animals; Atherosclerosis; Autophagy; Berberine; Disease Models, Animal; Dose-R

2020
Berberine inhibits proliferation and apoptosis of vascular smooth muscle cells induced by mechanical stretch via the PDI/ERS and MAPK pathways.
    Life sciences, 2020, Oct-15, Volume: 259

    Topics: Animals; Apoptosis; Atherosclerosis; Berberine; Cell Proliferation; Cells, Cultured; China; Endoplas

2020
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
    NPJ biofilms and microbiomes, 2021, 04-16, Volume: 7, Issue:1

    Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility;

2021
Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe
    Atherosclerosis, 2018, Volume: 268

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Aortic Diseases; Atherosclerosis; Berberine; Cytokines; Di

2018
Suppressive effects of berberine on atherosclerosis via downregulating visfatin expression and attenuating visfatin-induced endothelial dysfunction.
    International journal of molecular medicine, 2018, Volume: 41, Issue:4

    Topics: Animals; Atherosclerosis; Berberine; Cytokines; Down-Regulation; Endothelial Cells; Human Umbilical

2018
[Effects of the Traditional Chinese Medicine berberine on antiatheroscloresis and antioxidant activities in hyperlipoidemic model rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2017, Apr-08, Volume: 33, Issue:4

    Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Cholesterol; Drugs, Chinese Herbal; Glutathione P

2017
Berberine treatment reduces atherosclerosis by mediating gut microbiota in apoE-/- mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Berberine; Cytokines; Denaturing Gradient Gel Electroph

2018
Berberine ameliorates chronic kidney injury caused by atherosclerotic renovascular disease through the suppression of NFκB signaling pathway in rats.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Biomarkers; Fibrosis; Inflammation; Male; NF-kapp

2013
Berberine combined with atorvastatin downregulates LOX‑1 expression through the ET‑1 receptor in monocyte/macrophages.
    International journal of molecular medicine, 2014, Volume: 34, Issue:1

    Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Berberine; Body Weight; Cells, Cul

2014
The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1.
    International journal of molecular medicine, 2014, Volume: 34, Issue:4

    Topics: Adenylate Kinase; Atherosclerosis; Atorvastatin; Berberine; Cholesterol; Foam Cells; Heptanoic Acids

2014
The natural compound berberine positively affects macrophage functions involved in atherogenesis.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:2

    Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Berberine; Cell Membrane; Cells, Cultured; Chemo

2015
Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE(-/-) mice.
    Journal of translational medicine, 2014, Nov-26, Volume: 12

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Berberine; Cell Line; Humans; Mice; Mice, Knockout

2014
Simultaneous quantification and antiatherosclerosis effect of the traditional Korean medicine, Hwangryunhaedok-tang.
    BMC complementary and alternative medicine, 2015, Apr-08, Volume: 15

    Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Berberine Alkaloids; Biphenyl Compounds; Cell Pro

2015
Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE
    International immunopharmacology, 2017, Volume: 43

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Apolipoproteins E; Atherosclerosis; Berberin

2017
Berberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage.
    Cell death & disease, 2017, 01-19, Volume: 8, Issue:1

    Topics: Atherosclerosis; Autophagy; Berberine; Cell Survival; Cholesterol; Chromones; Humans; Lipids; Macrop

2017
Biochemical pathways in the antiatherosclerotic effect of berberine.
    Chinese medical journal, 2008, Jul-05, Volume: 121, Issue:13

    Topics: Atherosclerosis; Berberine; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Res

2008
Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway.
    Endocrine, 2008, Volume: 33, Issue:3

    Topics: Anilides; Atherosclerosis; Berberine; Cell Line; Chemokine CCL2; Humans; Hypoglycemic Agents; Interl

2008
Berberine promotes the development of atherosclerosis and foam cell formation by inducing scavenger receptor A expression in macrophage.
    Cell research, 2009, Volume: 19, Issue:8

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Berberine; Foam Cells; Macrophages; Mice; Mice, Inbred

2009
Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages.
    International journal of cardiology, 2011, Jan-21, Volume: 146, Issue:2

    Topics: Atherosclerosis; Basigin; Berberine; Carcinogens; Cell Line; Dose-Response Relationship, Drug; Human

2011
Effects of berberine on expression of LOX-1 and SR-BI in human macrophage-derived foam cells induced by ox-LDL.
    The American journal of Chinese medicine, 2010, Volume: 38, Issue:6

    Topics: Atherosclerosis; ATP-Binding Cassette Transporters; Berberine; Blotting, Western; Cell Line; Coptis;

2010
Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Acetyl-CoA Carboxylase; Aldehydes; AMP-Activated Protein Kinases; Animals; Aorta; Apolipoproteins E;

2011
The effects of berberine on hyperhomocysteinemia and hyperlipidemia in rats fed with a long-term high-fat diet.
    Lipids in health and disease, 2012, Jul-04, Volume: 11

    Topics: Animals; Aorta; Apolipoproteins; Atherosclerosis; Berberine; Cholesterol; Cholesterol, LDL; Diet, Hi

2012