berberine has been researched along with Arthritis, Rheumatoid in 12 studies
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine may inhibit the gene expression and production of pro-inflammatory cytokines by mononuclear cells in rheumatoid arthritis and healthy individuals without affecting cell viability." | 8.02 | Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals. ( Ghorbani, N; Mahmoudi, M; Rastin, M; Sahebari, M; Zamani, M; Zamani, S, 2021) |
| "Berberine is a nature-derived alkaloid compound with multiple pharmacological activities in different pathologies, including RA." | 6.72 | Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential. ( Huang, DN; Sun, H; Wang, XJ; Wu, FF; Zhang, AH, 2021) |
| "Berberine may potentially retard the progression of osteoporosis, osteoarthritis and rheumatoid arthritis." | 5.05 | Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms. ( Chin, KY; Ima-Nirwana, S; Wong, SK, 2020) |
| "The purpose of this study was to evaluate the drug delivery and therapeutic potential of berberine (Br) loaded nanoformulation in rheumatoid arthritis (RA)-induced animal model." | 4.31 | Assessment of anti-arthritic activity of lipid matrix encased berberine in rheumatic animal model. ( Kumar, D; Mishra, N; Pal, RR; Pandey, AK; Parashar, P; Raj, R; Saraf, SA; Singh, N; Singh, P; Singh, S, 2023) |
| "Berberine may inhibit the gene expression and production of pro-inflammatory cytokines by mononuclear cells in rheumatoid arthritis and healthy individuals without affecting cell viability." | 4.02 | Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals. ( Ghorbani, N; Mahmoudi, M; Rastin, M; Sahebari, M; Zamani, M; Zamani, S, 2021) |
| "Gefitinib-resistant (G-R) nonsmall-cell lung cancer (NSCLC) and rheumatoid arthritis (RA) were studied as conditions representative of malignant and proliferative diseases, respectively." | 3.88 | Suppression of Lipogenesis via Reactive Oxygen Species-AMPK Signaling for Treating Malignant and Proliferative Diseases. ( Fan, XX; Fu, J; He, JX; Huang, J; Jiang, ZB; Kam, RK; Leung, EL; Liu, L; Liu, ZQ; Lu, LL; Luo, LX; Wei, CL; Wu, JL; Xiao, DK; Xie, Y; Yao, XJ; Yuan, ZW; Zheng, YF; Zhou, YL, 2018) |
| "Berberine is a nature-derived alkaloid compound with multiple pharmacological activities in different pathologies, including RA." | 2.72 | Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential. ( Huang, DN; Sun, H; Wang, XJ; Wu, FF; Zhang, AH, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, N | 1 |
| Pandey, AK | 1 |
| Pal, RR | 1 |
| Parashar, P | 1 |
| Singh, P | 1 |
| Mishra, N | 1 |
| Kumar, D | 1 |
| Raj, R | 1 |
| Singh, S | 1 |
| Saraf, SA | 1 |
| Yue, M | 1 |
| Tao, Y | 1 |
| Fang, Y | 1 |
| Lian, X | 1 |
| Zhang, Q | 1 |
| Xia, Y | 1 |
| Wei, Z | 1 |
| Dai, Y | 1 |
| Sujitha, S | 2 |
| Dinesh, P | 1 |
| Rasool, M | 2 |
| Ghorbani, N | 1 |
| Sahebari, M | 1 |
| Mahmoudi, M | 1 |
| Rastin, M | 1 |
| Zamani, S | 1 |
| Zamani, M | 1 |
| Vita, AA | 1 |
| Aljobaily, H | 1 |
| Lyons, DO | 1 |
| Pullen, NA | 1 |
| Huang, DN | 1 |
| Wu, FF | 1 |
| Zhang, AH | 1 |
| Sun, H | 1 |
| Wang, XJ | 1 |
| Fan, XX | 1 |
| Leung, EL | 1 |
| Xie, Y | 1 |
| Liu, ZQ | 1 |
| Zheng, YF | 1 |
| Yao, XJ | 1 |
| Lu, LL | 1 |
| Wu, JL | 1 |
| He, JX | 1 |
| Yuan, ZW | 1 |
| Fu, J | 1 |
| Wei, CL | 1 |
| Huang, J | 1 |
| Xiao, DK | 1 |
| Luo, LX | 1 |
| Jiang, ZB | 1 |
| Zhou, YL | 1 |
| Kam, RK | 1 |
| Liu, L | 1 |
| Qiu, H | 1 |
| Sun, S | 1 |
| Ma, X | 1 |
| Cui, C | 1 |
| Chen, G | 1 |
| Liu, Z | 1 |
| Li, H | 1 |
| Liu, M | 1 |
| Wong, SK | 1 |
| Chin, KY | 1 |
| Ima-Nirwana, S | 1 |
| Wang, X | 1 |
| He, X | 1 |
| Zhang, CF | 1 |
| Guo, CR | 1 |
| Wang, CZ | 1 |
| Yuan, CS | 1 |
| Wang, XH | 1 |
| Jiang, SM | 1 |
| Sun, QW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label Phase II Trial of Gefitinib and Berberine in Patients With Advanced Non-small Cell Lung Cancer and Activating EGFR Mutations[NCT03486496] | Phase 2 | 50 participants (Anticipated) | Interventional | 2018-06-05 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for berberine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Berberine; Humans | 2021 |
Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms.
Topics: Animals; Arthritis, Rheumatoid; Berberine; beta Catenin; Humans; Musculoskeletal Diseases; NF-kappa | 2020 |
10 other studies available for berberine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Assessment of anti-arthritic activity of lipid matrix encased berberine in rheumatic animal model.
Topics: Animals; Arthritis, Rheumatoid; Berberine; Drug Carriers; Drug Delivery Systems; Lipids; Models, Ani | 2023 |
The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Berberine; Butyrates; Female; Gastrointesti | 2019 |
Berberine encapsulated PEG-coated liposomes attenuate Wnt1/β-catenin signaling in rheumatoid arthritis via miR-23a activation.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Berberine; beta Catenin; Female; Liposomes; | 2020 |
Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals.
Topics: Adult; Arthritis, Rheumatoid; Berberine; Cells, Cultured; Gene Expression; Humans; Interleukin-1beta | 2021 |
Berberine Delays Onset of Collagen-Induced Arthritis through T Cell Suppression.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; B-Lymphocytes; Berberine; Collagen Type II; | 2021 |
Suppression of Lipogenesis via Reactive Oxygen Species-AMPK Signaling for Treating Malignant and Proliferative Diseases.
Topics: AMP-Activated Protein Kinases; Arthritis, Rheumatoid; Berberine; Carcinoma, Non-Small-Cell Lung; Cel | 2018 |
Jatrorrhizine Hydrochloride Suppresses Proliferation, Migration, and Secretion of Synoviocytes In Vitro and Ameliorates Rat Models of Rheumatoid Arthritis In Vivo.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Berberine; Cell Line; Cell Movement; Cell Prol | 2018 |
Berberine coated mannosylated liposomes curtail RANKL stimulated osteoclastogenesis through the modulation of GSK3β pathway via upregulating miR-23a.
Topics: Aniline Compounds; Animals; Arthritis, Rheumatoid; Berberine; Cells, Cultured; Disease Models, Anima | 2019 |
Anti-arthritic effect of berberine on adjuvant-induced rheumatoid arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Berberine; Cytokines; Gene Expression Regu | 2017 |
Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Anti-Inflammatory Agents; Apoptosis; Arthritis, Rheumatoid; Berberine; Cell Cycle; Cell Cycle Protei | 2011 |