berberine has been researched along with Arthritis, Degenerative in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect of berberine, a natural plant product that can activate AMP-activated protein kinase (AMPK), on Osteoarthritis (OA) development and associated pain in mice." | 8.12 | Oral administration of berberine limits post-traumatic osteoarthritis development and associated pain via AMP-activated protein kinase (AMPK) in mice. ( Chen, D; Li, J; Liu-Bryan, R; Wang, Y, 2022) |
| "Berberine chloride (BBR) is an isoquinoline alkaloid that possesses promising protective efficacies against osteoarthritis (OA)." | 7.81 | In vivo anti-apoptosis activity of novel berberine-loaded chitosan nanoparticles effectively ameliorates osteoarthritis. ( He, B; Liu, SQ; Peng, H; Yu, L; Zhao, Q; Zhou, Y, 2015) |
| "Berberine was found to inhibit these signaling components in OASFs in vitro and prevent cartilage degradation in vivo." | 5.42 | Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis. ( Hung, CY; Lee, HP; Li, TM; Liu, SC; Tang, CH; Tsai, CH, 2015) |
| "Berberine was found to inhibit the expression of MMP-1, -3 and -13, and increased the level of TIMP-1 at the mRNA level in a dose-dependent manner." | 5.37 | Protective effects of berberine in an experimental rat osteoarthritis model. ( Bao, JP; Chen, WP; Hu, PF; Tang, JL; Wu, LD, 2011) |
| "Berberine may potentially retard the progression of osteoporosis, osteoarthritis and rheumatoid arthritis." | 5.05 | Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms. ( Chin, KY; Ima-Nirwana, S; Wong, SK, 2020) |
| "We investigated the effect of berberine, a natural plant product that can activate AMP-activated protein kinase (AMPK), on Osteoarthritis (OA) development and associated pain in mice." | 4.12 | Oral administration of berberine limits post-traumatic osteoarthritis development and associated pain via AMP-activated protein kinase (AMPK) in mice. ( Chen, D; Li, J; Liu-Bryan, R; Wang, Y, 2022) |
| "The low bioavailability and short biological half-life of berberine chloride (BBR) negatively affect the protective role of this compound against osteoarthritis (OA)." | 3.85 | Sustained release effects of berberine-loaded chitosan microspheres on in vitro chondrocyte culture. ( Deng, M; He, B; Li, Y; Liu, S; Ming, J; Zhou, Y, 2017) |
| "Berberine chloride (BBR) is an isoquinoline alkaloid that possesses promising protective efficacies against osteoarthritis (OA)." | 3.81 | In vivo anti-apoptosis activity of novel berberine-loaded chitosan nanoparticles effectively ameliorates osteoarthritis. ( He, B; Liu, SQ; Peng, H; Yu, L; Zhao, Q; Zhou, Y, 2015) |
| "Berberine was found to inhibit these signaling components in OASFs in vitro and prevent cartilage degradation in vivo." | 1.42 | Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis. ( Hung, CY; Lee, HP; Li, TM; Liu, SC; Tang, CH; Tsai, CH, 2015) |
| "Berberine was found to inhibit the expression of MMP-1, -3 and -13, and increased the level of TIMP-1 at the mRNA level in a dose-dependent manner." | 1.37 | Protective effects of berberine in an experimental rat osteoarthritis model. ( Bao, JP; Chen, WP; Hu, PF; Tang, JL; Wu, LD, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 2 |
| Wang, Y | 1 |
| Chen, D | 1 |
| Liu-Bryan, R | 1 |
| Lee, CK | 1 |
| Zhang, S | 1 |
| Venkatesan, G | 1 |
| Chong, SY | 1 |
| Wang, JW | 1 |
| Goh, WJ | 1 |
| Panczyk, T | 1 |
| Tay, YZ | 1 |
| Hu, J | 1 |
| Ng, WK | 1 |
| Wacker, MG | 1 |
| Toh, WS | 1 |
| Pastorin, G | 1 |
| Zhou, Y | 5 |
| Ming, J | 2 |
| Deng, M | 3 |
| Li, Y | 3 |
| Li, B | 1 |
| Ma, Y | 1 |
| Chen, Z | 1 |
| Liu, S | 3 |
| McCubrey, JA | 1 |
| Lertpiriyapong, K | 1 |
| Steelman, LS | 1 |
| Abrams, SL | 1 |
| Cocco, L | 1 |
| Ratti, S | 1 |
| Martelli, AM | 1 |
| Candido, S | 1 |
| Libra, M | 1 |
| Montalto, G | 1 |
| Cervello, M | 1 |
| Gizak, A | 1 |
| Rakus, D | 1 |
| He, B | 4 |
| Wong, SK | 1 |
| Chin, KY | 1 |
| Ima-Nirwana, S | 1 |
| Zhao, H | 1 |
| Zhang, T | 1 |
| Xia, C | 1 |
| Shi, L | 1 |
| Wang, S | 1 |
| Zheng, X | 1 |
| Hu, T | 1 |
| Zhang, B | 1 |
| Liu, SQ | 2 |
| Peng, H | 1 |
| Yu, L | 2 |
| Zhao, Q | 2 |
| Wu, SH | 1 |
| Xia, SQ | 1 |
| Mei, HJ | 1 |
| Liu, SC | 1 |
| Lee, HP | 1 |
| Hung, CY | 1 |
| Tsai, CH | 1 |
| Li, TM | 1 |
| Tang, CH | 1 |
| Tao, H | 1 |
| Xia, S | 1 |
| Zhang, C | 1 |
| Moon, PD | 1 |
| Jeong, HS | 1 |
| Chun, CS | 1 |
| Kim, HM | 1 |
| Hu, PF | 1 |
| Chen, WP | 1 |
| Tang, JL | 1 |
| Bao, JP | 1 |
| Wu, LD | 1 |
2 reviews available for berberine and Arthritis, Degenerative
| Article | Year |
|---|---|
Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.
Topics: Berberine; Cardiovascular Diseases; Curcumin; Gene Expression Regulation; Glycogen Synthase Kinase 3 | 2017 |
Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms.
Topics: Animals; Arthritis, Rheumatoid; Berberine; beta Catenin; Humans; Musculoskeletal Diseases; NF-kappa | 2020 |
11 other studies available for berberine and Arthritis, Degenerative
| Article | Year |
|---|---|
Oral administration of berberine limits post-traumatic osteoarthritis development and associated pain via AMP-activated protein kinase (AMPK) in mice.
Topics: Administration, Oral; AMP-Activated Protein Kinases; Animals; Arthralgia; Berberine; Joints; Male; M | 2022 |
Enhanced skin penetration of berberine from proniosome gel attenuates pain and inflammation in a mouse model of osteoarthritis.
Topics: Animals; Berberine; Chondrocytes; Gels; Inflammation; Mice; Osteoarthritis; Pain; Skin Absorption | 2022 |
Berberine-mediated up-regulation of surfactant protein D facilitates cartilage repair by modulating immune responses via the inhibition of TLR4/NF-ĸB signaling.
Topics: Animals; Berberine; Cartilage, Articular; Cells, Cultured; Chondrocytes; Immunologic Factors; Male; | 2020 |
Sustained release effects of berberine-loaded chitosan microspheres on in vitro chondrocyte culture.
Topics: Animals; Apoptosis; Berberine; Caspase 3; Chitosan; Chondrocytes; Delayed-Action Preparations; Half- | 2017 |
Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling.
Topics: Aggrecans; Animals; Animals, Newborn; Antigens, Nuclear; Berberine; Cartilage, Articular; Cell Proli | 2014 |
In vivo anti-apoptosis activity of novel berberine-loaded chitosan nanoparticles effectively ameliorates osteoarthritis.
Topics: Animals; Apoptosis; Berberine; Cartilage, Articular; Chitosan; Chondrocytes; Cross-Linking Reagents; | 2015 |
Berberine prevents nitric oxide-induced rat chondrocyte apoptosis and cartilage degeneration in a rat osteoarthritis model via AMPK and p38 MAPK signaling.
Topics: Alkaloids; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Apoptosis; Apoptosis Regulatory | 2015 |
Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Berberine; Cartilage; Cells, Cultured; Connective | 2015 |
Berberine promotes proliferation of sodium nitroprusside-stimulated rat chondrocytes and osteoarthritic rat cartilage via Wnt/β-catenin pathway.
Topics: Animals; Berberine; Cartilage, Articular; Cell Cycle; Cell Proliferation; Chondrocytes; Cyclin D1; C | 2016 |
Baekjeolyusin-tang and its active component berberine block the release of collagen and proteoglycan from IL-1β-stimulated rabbit cartilage and down-regulate matrix metalloproteinases in rabbit chondrocytes.
Topics: Animals; Atractylodes; Berberine; Cartilage; Chondrocytes; Collagen; Down-Regulation; Gene Expressio | 2011 |
Protective effects of berberine in an experimental rat osteoarthritis model.
Topics: Animals; Base Sequence; Berberine; Cartilage, Articular; Cell Proliferation; Chondrocytes; DNA Prime | 2011 |