Page last updated: 2024-10-23

berberine and Adenoma

berberine has been researched along with Adenoma in 5 studies

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" Individuals aged 18-75 years who had at least one but no more than six histologically confirmed colorectal adenomas that had undergone complete polypectomy within the 6 months before recruitment were recruited and randomly assigned (1:1) to receive berberine (0·3 g twice daily) or placebo tablets via block randomisation (block size of six)."9.34Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study. ( Cao, HL; Cao, XC; Chen, HM; Chen, YX; Dou, XT; Fang, JY; Gao, QY; Kang, Q; Li, N; Liu, SD; Liu, ZJ; Ren, JL; Sheng, JQ; Song, YY; Sun, XM; Wang, BM; Xiao, B; Xu, HZ; Yang, XN; Zhu, W; Zou, TH; Zou, XP, 2020)
"Berberine(BBR) is a kind of isoquinoline alkaloids extracted from the rhizomes of Coptis chinensis Franch."6.82Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis. ( Cao, Z; Du, S; Fang, S; Guo, S; Su, X; Wei, W; Yang, Y, 2022)
" Individuals aged 18-75 years who had at least one but no more than six histologically confirmed colorectal adenomas that had undergone complete polypectomy within the 6 months before recruitment were recruited and randomly assigned (1:1) to receive berberine (0·3 g twice daily) or placebo tablets via block randomisation (block size of six)."5.34Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study. ( Cao, HL; Cao, XC; Chen, HM; Chen, YX; Dou, XT; Fang, JY; Gao, QY; Kang, Q; Li, N; Liu, SD; Liu, ZJ; Ren, JL; Sheng, JQ; Song, YY; Sun, XM; Wang, BM; Xiao, B; Xu, HZ; Yang, XN; Zhu, W; Zou, TH; Zou, XP, 2020)
"Berberine(BBR) is a kind of isoquinoline alkaloids extracted from the rhizomes of Coptis chinensis Franch."2.82Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis. ( Cao, Z; Du, S; Fang, S; Guo, S; Su, X; Wei, W; Yang, Y, 2022)
"Accumulating evidence links colorectal cancer (CRC) with the intestinal microbiota."1.42Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment. ( An, HF; Chen, HM; Chen, HY; Fang, JY; Hong, J; Li, M; Ma, X; Qin, WX; Shen, N; Sun, TT; Weng, YR; Yu, J; Yu, TC; Yu, YN; Zhao, HJ, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's4 (80.00)2.80

Authors

AuthorsStudies
Fang, S1
Guo, S1
Du, S1
Cao, Z1
Yang, Y2
Su, X1
Wei, W1
Tan, S1
Ou, Y1
Huang, S1
Chen, S1
Gao, Q1
Chen, YX1
Gao, QY1
Zou, TH1
Wang, BM1
Liu, SD1
Sheng, JQ1
Ren, JL1
Zou, XP1
Liu, ZJ1
Song, YY1
Xiao, B1
Sun, XM1
Dou, XT1
Cao, HL1
Yang, XN1
Li, N1
Kang, Q1
Zhu, W1
Xu, HZ1
Chen, HM2
Cao, XC1
Fang, JY2
Kwon, S1
Chan, AT1
Yu, YN1
Yu, TC1
Zhao, HJ1
Sun, TT1
Chen, HY1
An, HF1
Weng, YR1
Yu, J1
Li, M1
Qin, WX1
Ma, X1
Shen, N1
Hong, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-controlled, Multicenter, Prospective Clinical Study of Berberine Hydrochloride in Preventing Recurrence and Carcinogenesis After Endoscopic Removal of Colorectal Adenomas[NCT02226185]Phase 2/Phase 31,108 participants (Actual)Interventional2014-11-30Completed
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis: a Prospective Cohort Study[NCT04543643]Phase 3288 participants (Anticipated)Interventional2021-11-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for berberine and Adenoma

ArticleYear
Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis.
    Journal of ethnopharmacology, 2022, Jan-10, Volume: 282

    Topics: Adenoma; Berberine; Colorectal Neoplasms; Coptis chinensis; Humans

2022
Preventive effects of chemical drugs on recurrence of colorectal adenomas: systematic review and Bayesian network meta-analysis.
    European journal of gastroenterology & hepatology, 2024, Jan-01, Volume: 36, Issue:1

    Topics: Adenoma; Berberine; Colorectal Neoplasms; Humans; Network Meta-Analysis; Randomized Controlled Trial

2024

Trials

1 trial available for berberine and Adenoma

ArticleYear
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Adenoma; Adolescent; Adult; Aftercare; Aged; Antineoplastic Agents, Phytogenic; Berberine; Chemoprev

2020
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Adenoma; Adolescent; Adult; Aftercare; Aged; Antineoplastic Agents, Phytogenic; Berberine; Chemoprev

2020
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Adenoma; Adolescent; Adult; Aftercare; Aged; Antineoplastic Agents, Phytogenic; Berberine; Chemoprev

2020
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Adenoma; Adolescent; Adult; Aftercare; Aged; Antineoplastic Agents, Phytogenic; Berberine; Chemoprev

2020

Other Studies

2 other studies available for berberine and Adenoma

ArticleYear
Extracting the benefits of berberine for colorectal cancer.
    The lancet. Gastroenterology & hepatology, 2020, Volume: 5, Issue:3

    Topics: Adenoma; Antineoplastic Agents, Phytogenic; Aspirin; Berberine; Cardiovascular Diseases; Case-Contro

2020
Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: Adenoma; Animals; Berberine; Blotting, Western; Cell Transformation, Neoplastic; Colorectal Neoplasm

2015