berbamine has been researched along with Granulocytic Leukemia, Chronic in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, Y; Wei, YL; Xu, L; Xu, XH; Zhao, XY | 1 |
| Liang, Y; Wei, YL; Xu, L; Zhao, XY | 1 |
| Liang, Y; Qiu, X; Xu, RZ; Zhao, XY | 1 |
| Chen, T; Fang, Y; Gan, X; Gan, Y; Gu, Y; Huang, L; Huang, W; Li, H; Lou, G; Meng, Z; Tang, J; Wang, K; Xu, G; Xu, R; Xu, X; Zhang, X; Zheng, S; Zhou, H | 1 |
| Dong, Q; Gan, X; Lu, Q; Wu, D; Xu, R; Xu, X; Yu, XF; Yu, Y; Zhao, X | 1 |
| Dong, QH; Fang, YM; Gu, Y; He, ZW; Lü, QH; Sun, JR; Xu, RZ; Yu, YZ; Zhang, XH | 1 |
| Hao, RR; Huang, WH; Liang, MH; Pan, YL; Shen, ZR; Zeng, SX | 1 |
1 review(s) available for berbamine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
The progress of small-molecules and degraders against BCR-ABL for the treatment of CML.
Topics: Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein Kinase Inhibitors; Pyrimidines | 2022 |
6 other study(ies) available for berbamine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Benzamides; Benzylisoquinolines; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrimidines | 2009 |
The antiproliferation effect of berbamine on k562 resistant cells by inhibiting NF-kappaB pathway.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Benzylisoquinolines; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; G1 Phase; Genes, abl; Humans; I-kappa B Proteins; Imatinib Mesylate; Indicators and Reagents; Inhibitor of Apoptosis Proteins; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microtubule-Associated Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Piperazines; Pyrimidines; RNA, Messenger; Signal Transduction; Survivin; Tetrazolium Salts | 2009 |
Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity.
Topics: Apoptosis; Benzylisoquinolines; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; G1 Phase; Gene Expression Regulation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Receptors, Transforming Growth Factor beta; Smad3 Protein | 2011 |
CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Benzylisoquinolines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; HEK293 Cells; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred NOD; Mice, SCID; Models, Molecular; Mutation; Neoplastic Stem Cells; Piperazines; Protein Binding; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
Berbamine: a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity.
Topics: Alkaloids; Apoptosis; Benzamides; Benzylisoquinolines; Bone Marrow Cells; Caspase 3; Caspases; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein Kinase Inhibitors; Pyrimidines | 2006 |
[The mechanism of apoptosis of chronic myeloid leukemia cells induced by the novel p210 bcr/abl inhibitor berbamine].
Topics: Alkaloids; Apoptosis; bcl-Associated Death Protein; Benzylisoquinolines; Caspase 3; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oncogene Proteins v-abl; Phytotherapy | 2006 |