bepridil has been researched along with Neoplasms in 3 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The presence of the NCX antigen in the cancer cells was proved by Western blotting, flow cytometry and confocal laser scanning microscopy." | 1.34 | Na+/Ca2+ exchanger inhibitors modify the accumulation of tumor-diagnostic PET tracers in cancer cells. ( Balkay, L; Friedlander, E; Krasznai, Z; Márián, T; Németh, E; Szabó, A; Szabó-Péli, J; Trón, L; Veress, G, 2007) |
| "Bepridil was administered in a continuous 36 h infusion at 22 mg/kg/36 h, with a dose scheme which should result in a steady state plasma concentration of approximately 5 mumol/l, able to reverse anthracycline resistance in vitro." | 1.28 | Bepridil in combination with anthracyclines to reverse anthracycline resistance in cancer patients. ( Blokhuis, WM; de Jong, J; Giaccone, G; Maessen, PA; Pinedo, HM; Schuurhuis, GJ; van der Hoeven, JJ; van der Vijgh, WJ; van Kalken, CK, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Márián, T | 1 |
| Szabó-Péli, J | 1 |
| Németh, E | 1 |
| Trón, L | 1 |
| Friedlander, E | 1 |
| Szabó, A | 1 |
| Balkay, L | 1 |
| Veress, G | 1 |
| Krasznai, Z | 1 |
| van Kalken, CK | 1 |
| van der Hoeven, JJ | 1 |
| de Jong, J | 1 |
| Giaccone, G | 1 |
| Schuurhuis, GJ | 1 |
| Maessen, PA | 1 |
| Blokhuis, WM | 1 |
| van der Vijgh, WJ | 1 |
| Pinedo, HM | 1 |
3 other studies available for bepridil and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Na+/Ca2+ exchanger inhibitors modify the accumulation of tumor-diagnostic PET tracers in cancer cells.
Topics: Bepridil; Calcium; Carbon Radioisotopes; Cell Line, Tumor; Choline; Flow Cytometry; Fluorodeoxygluco | 2007 |
Bepridil in combination with anthracyclines to reverse anthracycline resistance in cancer patients.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bepridil; | 1991 |