bepridil has been researched along with Myocardial Ischemia in 3 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of bepridil on silent myocardial ischemia and on eicosanoid metabolism, 10 patients with chronic stable angina underwent exercise treadmill testing and 48-hour ambulatory electrocardiographic monitoring both before and after 4 weeks of bepridil administration (150 mg/day)." | 9.07 | Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction. ( Hikita, H; Kanda, Y; Kurita, A; Maruyama, T; Mizuno, K; Nakamura, H; Nishioka, T; Takase, B; Uehata, A, 1994) |
| "To investigate the effects of bepridil on silent myocardial ischemia and on eicosanoid metabolism, 10 patients with chronic stable angina underwent exercise treadmill testing and 48-hour ambulatory electrocardiographic monitoring both before and after 4 weeks of bepridil administration (150 mg/day)." | 5.07 | Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction. ( Hikita, H; Kanda, Y; Kurita, A; Maruyama, T; Mizuno, K; Nakamura, H; Nishioka, T; Takase, B; Uehata, A, 1994) |
| "However, ventricular tachycardia (VT)/ventricular fibrillation (VF) occurred spontaneously and converted to sinus rhythm with direct current shock (300 J)." | 1.31 | [Successful hybrid therapy combined with oral bepridil and ICD in a patient with amiodarone refractory life-threatening ventricular tachyarrhythmia associated with ischemic cardiomyopathy]. ( Abe, H; Nakashima, Y; Oginosawa, Y; Okazaki, M; Suzuki, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oginosawa, Y | 1 |
| Abe, H | 1 |
| Suzuki, Y | 1 |
| Okazaki, M | 1 |
| Nakashima, Y | 1 |
| Tabouy, L | 1 |
| Chauvet-Monges, AM | 1 |
| Salducci, MD | 1 |
| Crevat, A | 1 |
| Takase, B | 1 |
| Kurita, A | 1 |
| Hikita, H | 1 |
| Uehata, A | 1 |
| Nishioka, T | 1 |
| Maruyama, T | 1 |
| Mizuno, K | 1 |
| Nakamura, H | 1 |
| Kanda, Y | 1 |
1 trial available for bepridil and Myocardial Ischemia
| Article | Year |
|---|---|
Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angina Pectoris; Arachidonic Acids; Bepridil; Chronic Dis | 1994 |
2 other studies available for bepridil and Myocardial Ischemia
| Article | Year |
|---|---|
[Successful hybrid therapy combined with oral bepridil and ICD in a patient with amiodarone refractory life-threatening ventricular tachyarrhythmia associated with ischemic cardiomyopathy].
Topics: Administration, Oral; Aged; Bepridil; Defibrillators, Implantable; Humans; Male; Myocardial Ischemia | 2002 |
Protective effect of some calcium antagonists against mitochondrial calcium injury.
Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Bloc | 1994 |