Page last updated: 2024-10-23

bepridil and Inflammation

bepridil has been researched along with Inflammation in 4 studies

Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Bepridil treatment did not significantly affect heme oxygenase-1- or NAD(P)H quinone oxidoreductase-1-mediated oxidative stress or inflammatory responses in the ipsilateral thalamus of MCAO rats."1.38Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats. ( Haapasalo, A; Hiltunen, M; Jolkkonen, J; Lipsanen, A; Mäkinen, P; Peräniemi, S; Sarajärvi, T; Soininen, H, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishino, M1
Mori, N1
Nakamura, D1
Lee, Y1
Yoshimura, T1
Taniike, M1
Makino, N1
Kato, H1
Egami, Y1
Shutta, R1
Tanouchi, J1
Yamada, Y1
Sarajärvi, T1
Lipsanen, A1
Mäkinen, P1
Peräniemi, S1
Soininen, H1
Haapasalo, A1
Jolkkonen, J1
Hiltunen, M1
Sandoval, M1
Ronzio, RA1
Muanza, DN1
Clark, DA1
Miller, MJ1
Nishidai, S1
Nakamura, Y1
Torikai, K1
Yamamoto, M1
Ishihara, N1
Mori, H1
Ohigashi, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Calcium Oxalate Urinary Stone Formation: a Randomised Controlled Trial[NCT02649140]50 participants (Anticipated)Interventional2015-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for bepridil and Inflammation

ArticleYear
Correlation between inflammation state and successful medical cardioversion using bepridil for refractory atrial fibrillation.
    Journal of cardiology, 2013, Volume: 62, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Biomarkers; C-Reactive Protein; Electri

2013
Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats.
    Journal of cellular and molecular medicine, 2012, Volume: 16, Issue:11

    Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Behavior, Animal; Bep

2012
Peroxynitrite-induced apoptosis in epithelial (T84) and macrophage (RAW 264.7) cell lines: effect of legume-derived polyphenols (phytolens).
    Nitric oxide : biology and chemistry, 1997, Volume: 1, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Bepridil; Biphenyl Compounds; Cell Division; Cell Line; Cell Survi

1997
Kurosu, a traditional vinegar produced from unpolished rice, suppresses lipid peroxidation in vitro and in mouse skin.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetic Acid; Animals; Antioxidants; Bepridil; Biphenyl Compounds;

2000