bepridil has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bepridil treatment did not significantly affect heme oxygenase-1- or NAD(P)H quinone oxidoreductase-1-mediated oxidative stress or inflammatory responses in the ipsilateral thalamus of MCAO rats." | 1.38 | Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats. ( Haapasalo, A; Hiltunen, M; Jolkkonen, J; Lipsanen, A; Mäkinen, P; Peräniemi, S; Sarajärvi, T; Soininen, H, 2012) |
| "To this aim, permanent middle cerebral artery occlusion (pMCAO) was performed in male rats." | 1.32 | Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats. ( Amoroso, S; Annunziato, L; Caliendo, G; Di Renzo, G; Giaccio, L; Pignataro, G; Santagada, V; Scorziello, A; Secondo, A; Severino, B; Tortiglione, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarajärvi, T | 1 |
| Lipsanen, A | 1 |
| Mäkinen, P | 1 |
| Peräniemi, S | 1 |
| Soininen, H | 1 |
| Haapasalo, A | 1 |
| Jolkkonen, J | 1 |
| Hiltunen, M | 1 |
| Pignataro, G | 1 |
| Tortiglione, A | 1 |
| Scorziello, A | 1 |
| Giaccio, L | 1 |
| Secondo, A | 1 |
| Severino, B | 1 |
| Santagada, V | 1 |
| Caliendo, G | 1 |
| Amoroso, S | 1 |
| Di Renzo, G | 1 |
| Annunziato, L | 1 |
2 other studies available for bepridil and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Behavior, Animal; Bep | 2012 |
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats.
Topics: Animals; Bepridil; Brain Ischemia; Dose-Response Relationship, Drug; Ferric Compounds; Infarction, M | 2004 |