bepridil has been researched along with Heart Failure in 3 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bepridil is a unique calcium antagonist with a broad pharmacologic profile and demonstrated efficacy as an antianginal agent." | 2.38 | Safety profile of bepridil determined from clinical trials in chronic stable angina in the United States. ( Singh, BN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, M | 1 |
| Takata, Y | 1 |
| Fukasawa, S | 1 |
| Sakota, K | 1 |
| Abe, T | 1 |
| Goseki, Y | 1 |
| Setoguchi, Y | 1 |
| Chikamori, T | 1 |
| Yamashina, A | 1 |
| Singh, BN | 1 |
| Silver, PJ | 1 |
| Monteforte, PB | 1 |
1 review available for bepridil and Heart Failure
| Article | Year |
|---|---|
Safety profile of bepridil determined from clinical trials in chronic stable angina in the United States.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Arrhythmias, Cardiac; Bepridil; Chronic Disease; El | 1992 |
2 other studies available for bepridil and Heart Failure
| Article | Year |
|---|---|
Two patients with bepridil-induced interstitial pneumonia.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Diagnosis, Differential; Heart Failure; | 2009 |
Differential effects of pharmacological modulators of cardiac myofibrillar ATPase activity in normal and myopathic (BIO 14.6) hamsters.
Topics: Adenosine Triphosphatases; Animals; Anti-Arrhythmia Agents; Bepridil; Calcium; Calcium Channel Block | 1988 |