bepridil has been researched along with Ebola Hemorrhagic Fever in 5 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results using an in vivo murine Ebola virus infection model confirmed the protective ability of several drugs, such as bepridil and sertraline." | 1.42 | A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. ( Delos, SE; DeWald, LE; Glass, PJ; Grenier, JM; Hensley, LE; Hoffstrom, BG; Johansen, LM; Lear-Rooney, CM; Lehár, J; Nelson, E; Olinger, GG; Pajouhesh, H; Pierce, LT; Shoemaker, CJ; Simmons, JA; Stossel, A; White, JM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, J | 1 |
| Zhao, Y | 1 |
| Fry, EE | 1 |
| Stuart, DI | 1 |
| Selaković, Ž | 1 |
| Tran, JP | 1 |
| Kota, KP | 1 |
| Lazić, M | 1 |
| Retterer, C | 1 |
| Besch, R | 1 |
| Panchal, RG | 1 |
| Soloveva, V | 1 |
| Sean, VA | 1 |
| Jay, WB | 1 |
| Pavić, A | 1 |
| Verbić, T | 1 |
| Vasiljević, B | 1 |
| Kuehl, K | 1 |
| Duplantier, AJ | 1 |
| Bavari, S | 1 |
| Mudhasani, R | 1 |
| Šolaja, BA | 1 |
| Morales-Tenorio, M | 1 |
| Ginex, T | 1 |
| Cuesta-Geijo, MÁ | 1 |
| Campillo, NE | 1 |
| Muñoz-Fontela, C | 1 |
| Alonso, C | 1 |
| Delgado, R | 1 |
| Gil, C | 1 |
| Han, S | 1 |
| Li, H | 1 |
| Chen, W | 1 |
| Yang, L | 1 |
| Tong, X | 1 |
| Zuo, J | 1 |
| Hu, Y | 1 |
| Johansen, LM | 1 |
| DeWald, LE | 1 |
| Shoemaker, CJ | 1 |
| Hoffstrom, BG | 1 |
| Lear-Rooney, CM | 1 |
| Stossel, A | 1 |
| Nelson, E | 1 |
| Delos, SE | 1 |
| Simmons, JA | 1 |
| Grenier, JM | 1 |
| Pierce, LT | 1 |
| Pajouhesh, H | 1 |
| Lehár, J | 1 |
| Hensley, LE | 1 |
| Glass, PJ | 1 |
| White, JM | 1 |
| Olinger, GG | 1 |
1 review available for bepridil and Ebola Hemorrhagic Fever
| Article | Year |
|---|---|
Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.
Topics: Antibodies; Ebolavirus; Glycoproteins; Hemorrhagic Fever, Ebola; Humans; Molecular Docking Simulatio | 2021 |
4 other studies available for bepridil and Ebola Hemorrhagic Fever
| Article | Year |
|---|---|
Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Ebolavirus; Glycoproteins; Hemorrhagic Fever, Ebola | 2018 |
Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action.
Topics: Animals; Antiviral Agents; Chrysenes; Ebolavirus; Hemorrhagic Fever, Ebola; Lysosomes; Mice; Surface | 2019 |
Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold.
Topics: Antiviral Agents; Ebolavirus; Hemorrhagic Fever, Ebola; HIV Fusion Inhibitors; Humans; Molecular Doc | 2022 |
A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.
Topics: Animals; Antiviral Agents; Bepridil; Drug Approval; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Mi | 2015 |