bepridil has been researched along with Chronic Kidney Failure in 3 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These products are well absorbed from the gastrointestinal tract but undergo variable degrees of transformation during the first passage through the liver." | 2.37 | [Clinical pharmacology of calcium inhibitors]. ( Martre, H; Singlas, E; Taburet, AM, 1985) |
| " Thus, no dosage adjustment will be required for ESRD patients and those receiving hemodialysis with cuprophane filters." | 1.29 | Pharmacokinetics of bepridil and two of its metabolites in patients with end-stage renal disease. ( Awni, WM; Desiraju, RK; Halstenson, CE; Matzke, GR; Minn, FL; Nayak, RK; Opsahl, JA, 1995) |
| "The effects of end-stage renal disease (ESRD) and hemodialysis on the in vitro plasma protein binding of bepridil hydrochloride were investigated." | 1.29 | Effects of hemodialysis on plasma protein binding of bepridil. ( Halstenson, CE; Matzke, GR; Nayak, RK; Opsahl, JA; Pritchard, JF, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Awni, WM | 1 |
| Halstenson, CE | 2 |
| Nayak, RK | 2 |
| Opsahl, JA | 2 |
| Desiraju, RK | 1 |
| Minn, FL | 1 |
| Matzke, GR | 2 |
| Pritchard, JF | 1 |
| Singlas, E | 1 |
| Martre, H | 1 |
| Taburet, AM | 1 |
1 review available for bepridil and Chronic Kidney Failure
| Article | Year |
|---|---|
[Clinical pharmacology of calcium inhibitors].
Topics: Age Factors; Animals; Bepridil; Biological Availability; Biotransformation; Calcium Channel Blockers | 1985 |
2 other studies available for bepridil and Chronic Kidney Failure
| Article | Year |
|---|---|
Pharmacokinetics of bepridil and two of its metabolites in patients with end-stage renal disease.
Topics: Administration, Oral; Adult; Bepridil; Female; Humans; Kidney Failure, Chronic; Middle Aged; Renal D | 1995 |
Effects of hemodialysis on plasma protein binding of bepridil.
Topics: Adult; Bepridil; Blood Proteins; Creatinine; Female; Humans; Kidney Failure, Chronic; Middle Aged; O | 1995 |