Page last updated: 2024-10-23

bepridil and Cerebral Ischemia

bepridil has been researched along with Cerebral Ischemia in 3 studies

Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.

Research Excerpts

ExcerptRelevanceReference
"To this aim, permanent middle cerebral artery occlusion (pMCAO) was performed in male rats."1.32Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats. ( Amoroso, S; Annunziato, L; Caliendo, G; Di Renzo, G; Giaccio, L; Pignataro, G; Santagada, V; Scorziello, A; Secondo, A; Severino, B; Tortiglione, A, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lipsanen, A1
Flunkert, S1
Kuptsova, K1
Hiltunen, M1
Windisch, M1
Hutter-Paier, B1
Jolkkonen, J1
Tortiglione, A2
Pignataro, G2
Minale, M1
Secondo, A2
Scorziello, A2
Di Renzo, GF1
Amoroso, S2
Caliendo, G2
Santagada, V2
Annunziato, L2
Giaccio, L1
Severino, B1
Di Renzo, G1

Other Studies

3 other studies available for bepridil and Cerebral Ischemia

ArticleYear
Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Bepridil; Brain Ischemia; Calcium Channel Blockers; Intracranial Thr

2013
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia.
    Annals of the New York Academy of Sciences, 2002, Volume: 976

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Bepridil; Biological Transport; Brain Ischemia; Calcium

2002
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats.
    Neuropharmacology, 2004, Volume: 46, Issue:3

    Topics: Animals; Bepridil; Brain Ischemia; Dose-Response Relationship, Drug; Ferric Compounds; Infarction, M

2004