bepridil has been researched along with Cardiomyopathy, Hypertrophic in 2 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bepridil inhibit IKr, IKs and IK1 in hypertrophied guinea pig ventricular myocytes, which may be important in understanding the antiarrhythmic effects of this drug." | 1.31 | [Bepridil inhibition on the delayed rectifier K+ currents in thyroxine induced hypertrophied guinea pig ventricular myocytes]. ( Dai, DZ; Hao, XM; Ma, YP; Wu, CH; Zhang, GQ; Zhou, PA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, GQ | 1 |
| Hao, XM | 1 |
| Ma, YP | 1 |
| Zhou, PA | 1 |
| Wu, CH | 1 |
| Dai, DZ | 1 |
| Haerer, W | 1 |
| Weritz, D | 1 |
| Stauch, M | 1 |
2 other studies available for bepridil and Cardiomyopathy, Hypertrophic
| Article | Year |
|---|---|
[Bepridil inhibition on the delayed rectifier K+ currents in thyroxine induced hypertrophied guinea pig ventricular myocytes].
Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Cardiomyopathy, Hypertrophic; Cell Separation; Delayed Re | 2001 |
Bepridil in hypertrophic obstructive cardiomyopathy.
Topics: Bepridil; Cardiomyopathy, Hypertrophic; Humans; Pyrrolidines | 1987 |