bepridil has been researched along with Brain Neoplasms in 2 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of bepridil and benzamil, known Na(+)-Ca2+ exchange blockers, on the growth of human brain tumor cells were evaluated using SK-N-MC human neuroblastoma and U-373 MG human astrocytoma cells as model cellular systems." | 3.69 | Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells. ( Lee, YS; Sayeed, MM; Wurster, RD, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, YS | 2 |
| Sayeed, MM | 1 |
| Wurster, RD | 2 |
2 other studies available for bepridil and Brain Neoplasms
| Article | Year |
|---|---|
Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells.
Topics: Amiloride; Astrocytoma; Bepridil; Brain Neoplasms; Calcium; Cell Division; Cytoplasm; Humans; Neurob | 1995 |
Bepridil enhances in vitro antitumor activity of antiestrogens in human brain tumor cells.
Topics: Bepridil; Brain Neoplasms; Calcium Channel Blockers; Cell Division; Clomiphene; Drug Synergism; Estr | 1996 |