bepridil has been researched along with Brain Ischemia in 3 studies
Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
bepridil : A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To this aim, permanent middle cerebral artery occlusion (pMCAO) was performed in male rats." | 1.32 | Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats. ( Amoroso, S; Annunziato, L; Caliendo, G; Di Renzo, G; Giaccio, L; Pignataro, G; Santagada, V; Scorziello, A; Secondo, A; Severino, B; Tortiglione, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lipsanen, A | 1 |
| Flunkert, S | 1 |
| Kuptsova, K | 1 |
| Hiltunen, M | 1 |
| Windisch, M | 1 |
| Hutter-Paier, B | 1 |
| Jolkkonen, J | 1 |
| Tortiglione, A | 2 |
| Pignataro, G | 2 |
| Minale, M | 1 |
| Secondo, A | 2 |
| Scorziello, A | 2 |
| Di Renzo, GF | 1 |
| Amoroso, S | 2 |
| Caliendo, G | 2 |
| Santagada, V | 2 |
| Annunziato, L | 2 |
| Giaccio, L | 1 |
| Severino, B | 1 |
| Di Renzo, G | 1 |
3 other studies available for bepridil and Brain Ischemia
| Article | Year |
|---|---|
Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion.
Topics: Amyloid beta-Peptides; Animals; Bepridil; Brain Ischemia; Calcium Channel Blockers; Intracranial Thr | 2013 |
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bepridil; Biological Transport; Brain Ischemia; Calcium | 2002 |
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats.
Topics: Animals; Bepridil; Brain Ischemia; Dose-Response Relationship, Drug; Ferric Compounds; Infarction, M | 2004 |