benzyl isothiocyanate has been researched along with Neoplasm Metastasis in 6 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzyl isothiocyanate (BITC) has been reported to exhibit antitumor properties in various cancer types; however, the underlying mechanisms of its action remain unclear." | 1.51 | Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway. ( Chen, J; Fan, L; Fan, W; Fu, S; Guo, L; Lin, L; Liu, H; Wang, B; Wei, H; Xie, B; Zhao, L, 2019) |
| "In this study, we investigated anti-metastasis effects of BITC and PEITC in melanoma cancer cells in vitro." | 1.46 | Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. ( Chiang, TA; Chung, JG; Hsiao, YT; Huang, YP; Lai, KC; Ma, YS; Yang, JL, 2017) |
| "This may provide a novel approach for metastasis therapy of lung cancer by dietary isothiocyanates and possibly other types of cancer." | 1.37 | Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates. ( Li, Y; Liu, B; Wu, H; Wu, X; Xu, K; Yan, H; Zhou, Q; Zhu, Y, 2011) |
| "Benzyl isothiocyanate (BITC) is a hydrolysis compound of glucotropaeolin in cruciferous vegetables." | 1.35 | Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells. ( Hwang, ES; Lee, HJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, KC | 2 |
| Hsiao, YT | 1 |
| Yang, JL | 1 |
| Ma, YS | 1 |
| Huang, YP | 1 |
| Chiang, TA | 1 |
| Chung, JG | 2 |
| Xie, B | 1 |
| Zhao, L | 1 |
| Guo, L | 1 |
| Liu, H | 1 |
| Fu, S | 1 |
| Fan, W | 1 |
| Lin, L | 1 |
| Chen, J | 1 |
| Wang, B | 1 |
| Fan, L | 1 |
| Wei, H | 1 |
| Lee, CS | 1 |
| Cho, HJ | 1 |
| Jeong, YJ | 1 |
| Shin, JM | 1 |
| Park, KK | 1 |
| Park, YY | 1 |
| Bae, YS | 1 |
| Chung, IK | 1 |
| Kim, M | 1 |
| Kim, CH | 1 |
| Jin, F | 1 |
| Chang, HW | 1 |
| Chang, YC | 1 |
| Huang, AC | 1 |
| Hsu, SC | 1 |
| Kuo, CL | 1 |
| Yang, JS | 1 |
| Wu, SH | 1 |
| Yan, H | 1 |
| Zhu, Y | 1 |
| Liu, B | 1 |
| Wu, H | 1 |
| Li, Y | 1 |
| Wu, X | 1 |
| Zhou, Q | 1 |
| Xu, K | 1 |
| Hwang, ES | 1 |
| Lee, HJ | 1 |
6 other studies available for benzyl isothiocyanate and Neoplasm Metastasis
| Article | Year |
|---|---|
Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic | 2017 |
Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway.
Topics: Animals; Apoptosis; beta Catenin; Breast Neoplasms; Cadherins; Cell Movement; Cell Proliferation; Fe | 2019 |
Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.
Topics: Cell Line, Tumor; Cell Movement; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regu | 2015 |
Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Topics: Base Sequence; DNA Primers; Enzyme Inhibitors; HT29 Cells; Humans; Isothiocyanates; MAP Kinase Signa | 2010 |
Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cel | 2011 |
Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Down-Regulation; | 2008 |