benzyl isothiocyanate has been researched along with Melanoma in 4 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to determine the role of phenethyl and benzyl isothiocyanates in modulating histone acetylation and methylation as a potential epigenetic therapeutic strategy in an in vitro model of malignant melanoma." | 8.02 | Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma. ( Anestopoulos, I; Franco, R; Kyriakou, S; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT, 2021) |
| " The aim of this study was to determine the role of phenethyl and benzyl isothiocyanates in modulating histone acetylation and methylation as a potential epigenetic therapeutic strategy in an in vitro model of malignant melanoma." | 4.02 | Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma. ( Anestopoulos, I; Franco, R; Kyriakou, S; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitsiogianni, M | 1 |
| Anestopoulos, I | 1 |
| Kyriakou, S | 1 |
| Trafalis, DT | 1 |
| Franco, R | 1 |
| Pappa, A | 1 |
| Panayiotidis, MI | 1 |
| Ma, YS | 1 |
| Hsiao, YT | 1 |
| Lin, JJ | 1 |
| Liao, CL | 1 |
| Lin, CC | 1 |
| Chung, JG | 2 |
| Sahu, RP | 1 |
| Huang, SH | 1 |
| Wu, LW | 1 |
| Huang, AC | 1 |
| Yu, CC | 1 |
| Lien, JC | 1 |
| Huang, YP | 1 |
| Yang, JS | 1 |
| Yang, JH | 1 |
| Hsiao, YP | 1 |
| Wood, WG | 1 |
| Yu, CS | 1 |
4 other studies available for benzyl isothiocyanate and Melanoma
| Article | Year |
|---|---|
Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma.
Topics: Acetylation; Cell Line, Tumor; Cell Survival; Epigenesis, Genetic; Histones; Humans; Isothiocyanates | 2021 |
Phenethyl Isothiocyanate (PEITC) and Benzyl Isothiocyanate (BITC) Inhibit Human Melanoma A375.S2 Cell Migration and Invasion by Affecting MAPK Signaling Pathway
Topics: Anticarcinogenic Agents; Apoptosis; Cell Movement; Cell Proliferation; Gene Expression Regulation, N | 2017 |
Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cells.
Topics: Animals; Apoptosis; Azepines; Cell Line; Cell Proliferation; Gene Expression Regulation; Humans; Iso | 2015 |
Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
Topics: Apoptosis; bcl-2-Associated X Protein; Calcium; Cardiolipins; Caspase 3; CDC2 Protein Kinase; cdc25 | 2012 |