benzyl isothiocyanate has been researched along with Liver Neoplasms in 7 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzyl isothiocyanate (BITC) is a dietary isothiocyanate derived from cruciferous vegetables." | 5.43 | Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells. ( Chen, Y; Dong, X; Guo, J; Li, M; Li, W; Lin, B; Lu, Y; Zhang, X; Zhu, M, 2016) |
| " Benzyl isothiocyanate (BITC) showed the inhibitory effect of tumor and AGPS activity, therefore, we screened a group of small molecular compound based on BITC by computer-aid design targeting AGPS and the results showed that the derivants could suppress the proliferation, the expression of tumor related genes such as survivin and Bcl-2, and the level of ether lipids such as lysophosphatidic acid ether (LPAe) and platelet activating factor ether (PAFe); however, the activity of caspase-3/8 was improved in glioma U87MG and hepatic carcinoma HepG2 cells in vitro." | 3.81 | Inhibitory effect of isothiocyanate derivant targeting AGPS by computer-aid drug design on proliferation of glioma and hepatic carcinoma cells. ( Li, WM; Xue, J; Yang, P; Zhang, L; Zhao, M; Zhu, Y, 2015) |
| "Benzyl isothiocyanate (BITC) is a member of the isothiocyanate compounds that found in cruciferous vegetables." | 1.48 | Chemopreventive and antitumor effects of benzyl isothiocynate on HCC models: A possible role of HGF /pAkt/ STAT3 axis and VEGF. ( Helmy, MW; Omran, G; Salahuddin, A; Zakaria, S, 2018) |
| "Benzyl isothiocyanate (BITC) is a dietary isothiocyanate derived from cruciferous vegetables." | 1.43 | Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells. ( Chen, Y; Dong, X; Guo, J; Li, M; Li, W; Lin, B; Lu, Y; Zhang, X; Zhu, M, 2016) |
| "Benzyl isothiocyanate (BITC) is a hydrolysis compound of glucotropaeolin in cruciferous vegetables." | 1.35 | Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells. ( Hwang, ES; Lee, HJ, 2008) |
| "Liver neoplasms were seen in Groups 1, 2 and 3." | 1.29 | Inhibitory effects of benzyl isothiocyanate and benzyl thiocyanate on diethylnitrosamine-induced hepatocarcinogenesis in rats. ( Mori, H; Okumura, A; Sugie, S; Tanaka, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zakaria, S | 1 |
| Helmy, MW | 1 |
| Salahuddin, A | 1 |
| Omran, G | 1 |
| Kim, M | 1 |
| Cho, HJ | 1 |
| Kwon, GT | 1 |
| Kang, YH | 1 |
| Kwon, SH | 1 |
| Her, S | 1 |
| Park, T | 1 |
| Kim, Y | 1 |
| Kee, Y | 1 |
| Park, JH | 1 |
| Zhu, Y | 1 |
| Li, WM | 1 |
| Zhang, L | 1 |
| Xue, J | 1 |
| Zhao, M | 1 |
| Yang, P | 1 |
| Zhu, M | 1 |
| Li, W | 1 |
| Guo, J | 1 |
| Lu, Y | 1 |
| Dong, X | 1 |
| Lin, B | 1 |
| Chen, Y | 1 |
| Zhang, X | 1 |
| Li, M | 1 |
| Scharf, G | 1 |
| Prustomersky, S | 1 |
| Knasmuller, S | 1 |
| Schulte-Hermann, R | 1 |
| Huber, WW | 1 |
| Hwang, ES | 1 |
| Lee, HJ | 1 |
| Sugie, S | 1 |
| Okumura, A | 1 |
| Tanaka, T | 1 |
| Mori, H | 1 |
7 other studies available for benzyl isothiocyanate and Liver Neoplasms
| Article | Year |
|---|---|
Chemopreventive and antitumor effects of benzyl isothiocynate on HCC models: A possible role of HGF /pAkt/ STAT3 axis and VEGF.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Caspase 3; | 2018 |
Benzyl isothiocyanate suppresses high-fat diet-stimulated mammary tumor progression via the alteration of tumor microenvironments in obesity-resistant BALB/c mice.
Topics: 3T3-L1 Cells; Animals; Cell Cycle; Cell Line; Dietary Fats; Female; Gene Expression Regulation, Neop | 2015 |
Inhibitory effect of isothiocyanate derivant targeting AGPS by computer-aid drug design on proliferation of glioma and hepatic carcinoma cells.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Ce | 2015 |
Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells.
Topics: alpha-Fetoproteins; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Movement | 2016 |
Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
Topics: 4-Butyrolactone; Allyl Compounds; Animals; Anticarcinogenic Agents; Cell Line, Tumor; Diterpenes; Do | 2003 |
Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Down-Regulation; | 2008 |
Inhibitory effects of benzyl isothiocyanate and benzyl thiocyanate on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Diethylnitrosamine; gamma-Glutamyltransferase; Glutathione Transfe | 1993 |