benzyl isothiocyanate has been researched along with Glial Cell Tumors in 5 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzyl isothiocyanate (BITC) has been shown to have inhibitory potential for human glioma U87MG cells; however, the effect and mechanism were not fully clear." | 7.81 | The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line. ( Liu, A; Liu, Y; Qi, L; Xue, J; Yang, P; Zhang, L; Zhang, X; Zhu, Y, 2015) |
| "Glioma is one of the most common tumors in China and chemotherapy is critical for its treatment." | 5.40 | Potential mechanisms of benzyl isothiocyanate suppression of invasion and angiogenesis by the U87MG human glioma cell line. ( Jiang, Y; Li, Q; Liu, MY; Qi, LS; Wang, HO; Yang, P; Zhang, GD; Zhang, L; Zhu, Y, 2014) |
| "Malignant glioma, also known as brain cancer, is the most common intracranial tumor, having an extremely high mortality and recurrence rate." | 5.39 | Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells. ( Wang, Q; Yang, P; Zhang, HY; Zhu, Y; Zhuang, JX, 2013) |
| "Benzyl isothiocyanate (BITC) has been shown to have inhibitory potential for human glioma U87MG cells; however, the effect and mechanism were not fully clear." | 3.81 | The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line. ( Liu, A; Liu, Y; Qi, L; Xue, J; Yang, P; Zhang, L; Zhang, X; Zhu, Y, 2015) |
| " Benzyl isothiocyanate (BITC) showed the inhibitory effect of tumor and AGPS activity, therefore, we screened a group of small molecular compound based on BITC by computer-aid design targeting AGPS and the results showed that the derivants could suppress the proliferation, the expression of tumor related genes such as survivin and Bcl-2, and the level of ether lipids such as lysophosphatidic acid ether (LPAe) and platelet activating factor ether (PAFe); however, the activity of caspase-3/8 was improved in glioma U87MG and hepatic carcinoma HepG2 cells in vitro." | 3.81 | Inhibitory effect of isothiocyanate derivant targeting AGPS by computer-aid drug design on proliferation of glioma and hepatic carcinoma cells. ( Li, WM; Xue, J; Yang, P; Zhang, L; Zhao, M; Zhu, Y, 2015) |
| "Glioma is one of the most common tumors in China and chemotherapy is critical for its treatment." | 1.40 | Potential mechanisms of benzyl isothiocyanate suppression of invasion and angiogenesis by the U87MG human glioma cell line. ( Jiang, Y; Li, Q; Liu, MY; Qi, LS; Wang, HO; Yang, P; Zhang, GD; Zhang, L; Zhu, Y, 2014) |
| "Malignant glioma, also known as brain cancer, is the most common intracranial tumor, having an extremely high mortality and recurrence rate." | 1.39 | Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells. ( Wang, Q; Yang, P; Zhang, HY; Zhu, Y; Zhuang, JX, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, Y | 4 |
| Zhuang, JX | 1 |
| Wang, Q | 1 |
| Zhang, HY | 1 |
| Yang, P | 4 |
| Zhang, L | 3 |
| Zhang, GD | 1 |
| Wang, HO | 1 |
| Liu, MY | 1 |
| Jiang, Y | 1 |
| Qi, LS | 1 |
| Li, Q | 1 |
| Liu, A | 1 |
| Zhang, X | 1 |
| Qi, L | 1 |
| Xue, J | 2 |
| Liu, Y | 1 |
| Li, WM | 1 |
| Zhao, M | 1 |
| Lee, CS | 1 |
| Cho, HJ | 1 |
| Jeong, YJ | 1 |
| Shin, JM | 1 |
| Park, KK | 1 |
| Park, YY | 1 |
| Bae, YS | 1 |
| Chung, IK | 1 |
| Kim, M | 1 |
| Kim, CH | 1 |
| Jin, F | 1 |
| Chang, HW | 1 |
| Chang, YC | 1 |
5 other studies available for benzyl isothiocyanate and Glial Cell Tumors
| Article | Year |
|---|---|
Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells.
Topics: Apoptosis; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Proliferation; Flow Cytometry; Gliom | 2013 |
Potential mechanisms of benzyl isothiocyanate suppression of invasion and angiogenesis by the U87MG human glioma cell line.
Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms; Cell Adhesion; Cell Cycle; Cell Mo | 2014 |
The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line.
Topics: Alkyl and Aryl Transferases; Animals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glio | 2015 |
Inhibitory effect of isothiocyanate derivant targeting AGPS by computer-aid drug design on proliferation of glioma and hepatic carcinoma cells.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Ce | 2015 |
Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.
Topics: Cell Line, Tumor; Cell Movement; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regu | 2015 |