benzyl isothiocyanate has been researched along with Colorectal Cancer in 5 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has previously been observed that allyl isothiocyanate, a compound naturally present in the diet, is more cytotoxic toward the human colorectal adenocarcinoma cell line HT29 in its control transformed state than after exposure to sodium butyrate or to dimethylformamide, which slow growth and induce differentiation (detransformation)." | 3.69 | Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. ( Fyfe, D; Johnson, IT; Musk, SR; Smith, TK; Stening, P; Stephenson, P, 1995) |
| " However, whereas it increased the number of aberrations four-fold, it was not able to raise SCE levels by more than 50% and there was a levelling-off in the dose-response curve." | 1.29 | Cytotoxic and clastogenic effects of benzyl isothiocyanate towards cultured mammalian cells. ( Astley, SB; Edwards, SM; Hubert, RB; Johnson, IT; Musk, SR; Stephenson, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Q | 2 |
| Nakamura, T | 2 |
| Seto, M | 1 |
| Miyagawa, M | 2 |
| Xu, W | 1 |
| Zhu, B | 2 |
| Munemasa, S | 2 |
| Murata, Y | 2 |
| Nakamura, Y | 2 |
| Liu, X | 1 |
| Kim, M | 1 |
| Murakami, A | 1 |
| Ohigashi, H | 1 |
| Musk, SR | 2 |
| Astley, SB | 1 |
| Edwards, SM | 1 |
| Stephenson, P | 2 |
| Hubert, RB | 1 |
| Johnson, IT | 2 |
| Smith, TK | 1 |
| Stening, P | 1 |
| Fyfe, D | 1 |
5 other studies available for benzyl isothiocyanate and Colorectal Cancer
| Article | Year |
|---|---|
A multidrug resistance-associated protein inhibitor is a potential enhancer of the benzyl isothiocyanate-induced apoptosis induction in human colorectal cancer cells.
Topics: Apoptosis; Colorectal Neoplasms; HCT116 Cells; Humans; Isothiocyanates; Multidrug Resistance-Associa | 2021 |
Methyl-β-cyclodextrin potentiates the BITC-induced anti-cancer effect through modulation of the Akt phosphorylation in human colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; beta-Cyclodextrins; Cell Line, Tumor; Cell Proliferation; Choleste | 2018 |
Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
Topics: Acetylcysteine; Antioxidants; Catechin; Colorectal Neoplasms; Culture Media; Curcumin; Gallic Acid; | 2007 |
Cytotoxic and clastogenic effects of benzyl isothiocyanate towards cultured mammalian cells.
Topics: Adenocarcinoma; Animals; Cell Survival; CHO Cells; Chromosome Aberrations; Colorectal Neoplasms; Cri | 1995 |
Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29.
Topics: Adenocarcinoma; Allyl Compounds; Anticarcinogenic Agents; Butyrates; Butyric Acid; Cell Differentiat | 1995 |