benzyl isothiocyanate has been researched along with Bladder Cancer in 7 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzyl isothiocyanate (BITC) is known for its pharmacological properties against malignant neoplasm, including bladder cancer (BC)." | 7.91 | Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells. ( Chen, HE; Chou, KY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2019) |
| "Because human urinary bladder cancers occur almost exclusively in the bladder epithelium, which is directly exposed to the urine stored in the bladder, we undertook to examine the anti-cancer activity of NAC-ITCs in cultured human bladder cancer cells." | 5.33 | The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells. ( Li, G; Song, L; Tang, L; Zhang, Y, 2006) |
| "Benzyl isothiocyanate (BITC) is known for its pharmacological properties against malignant neoplasm, including bladder cancer (BC)." | 3.91 | Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells. ( Chen, HE; Chou, KY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2019) |
| "Because human urinary bladder cancers occur almost exclusively in the bladder epithelium, which is directly exposed to the urine stored in the bladder, we undertook to examine the anti-cancer activity of NAC-ITCs in cultured human bladder cancer cells." | 1.33 | The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells. ( Li, G; Song, L; Tang, L; Zhang, Y, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, TF | 2 |
| Chen, PC | 1 |
| Lin, YC | 2 |
| Chou, KY | 2 |
| Chen, HE | 2 |
| Ho, CY | 1 |
| Lin, JF | 2 |
| Hwang, TI | 2 |
| Okazaki, K | 2 |
| Yamagishi, M | 1 |
| Son, HY | 1 |
| Imazawa, T | 2 |
| Furukawa, F | 1 |
| Nakamura, H | 1 |
| Nishikawa, A | 2 |
| Masegi, T | 2 |
| Hirose, M | 3 |
| Umemura, T | 1 |
| Li, J | 1 |
| Yao, S | 1 |
| Zhang, Y | 2 |
| Tang, L | 1 |
| Li, G | 1 |
| Song, L | 1 |
| Yamaguchi, T | 1 |
| Kimoto, N | 1 |
| Ogawa, K | 1 |
| Futakuchi, M | 1 |
| Sano, M | 1 |
| Shirai, T | 1 |
7 other studies available for benzyl isothiocyanate and Bladder Cancer
| Article | Year |
|---|---|
Benzyl isothiocyanate promotes miR-99a expression through ERK/AP-1-dependent pathway in bladder cancer cells.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Extracellular Signal-Re | 2020 |
Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; | 2019 |
Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitrosamine; Isothiocyanates; Male; | 2002 |
Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Drug Combinations; Hyperplasia; Isothio | 2003 |
The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates.
Topics: Anticarcinogenic Agents; Biotransformation; Blotting, Western; Carcinogens; Cell Line, Tumor; DNA, N | 2005 |
The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.
Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; | 2006 |
Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Diethylnitrosamine; Drug Synergism; Hyperp | 1998 |