benzyl isothiocyanate has been researched along with Adenocarcinoma in 10 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have shown previously that cruciferous vegetable constituent benzyl isothiocyanate (BITC) suppresses viability of cultured MCF-7 and MDA-MB-231 human breast cancer cells and retards mammary cancer development in MMTV-neu mice by causing apoptosis, but the mechanism of cell death is not fully understood." | 7.76 | p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression. ( Kim, SH; Singh, SV, 2010) |
| "We have shown previously that cruciferous vegetable constituent benzyl isothiocyanate (BITC) suppresses viability of cultured MCF-7 and MDA-MB-231 human breast cancer cells and retards mammary cancer development in MMTV-neu mice by causing apoptosis, but the mechanism of cell death is not fully understood." | 3.76 | p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression. ( Kim, SH; Singh, SV, 2010) |
| "It has previously been observed that allyl isothiocyanate, a compound naturally present in the diet, is more cytotoxic toward the human colorectal adenocarcinoma cell line HT29 in its control transformed state than after exposure to sodium butyrate or to dimethylformamide, which slow growth and induce differentiation (detransformation)." | 3.69 | Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. ( Fyfe, D; Johnson, IT; Musk, SR; Smith, TK; Stening, P; Stephenson, P, 1995) |
| "Exposure of prostate cancer cells (LNCaP, 22Rv1, C4-2, and PC-3) to pharmacologically applicable concentrations of PEITC, benzyl isothiocyanate (BITC), and SFN (2." | 1.42 | CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells. ( Amjad, AI; Chinni, SR; Parikh, R; Sakao, K; Singh, SV; Vyas, AR, 2015) |
| "Benzyl isothiocyanate (BITC) is an important compound found in plant food and has been shown to have anti-cancer effects on human cancer cells, but its effect on prostate cancer cells in vitro remains unknown." | 1.37 | The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway. ( Chiu, TH; Chueh, FS; Chung, JG; Huang, YT; Ji, BC; Liu, KC; Wu, PP; Yang, JL; Yang, JS, 2011) |
| "Using adenocarcinoma and metastatic pancreatic cancer cells, we investigated whether this dietary isothiocyanate induces apoptosis by converging two major pathways: the death receptor-mediated extrinsic and the mitochondrial intrinsic pathway." | 1.35 | Anti-proliferative and proapoptotic effects of benzyl isothiocyanate on human pancreatic cancer cells is linked to death receptor activation and RasGAP/Rac1 down-modulation. ( Basu, A; Haldar, S, 2009) |
| " However, whereas it increased the number of aberrations four-fold, it was not able to raise SCE levels by more than 50% and there was a levelling-off in the dose-response curve." | 1.29 | Cytotoxic and clastogenic effects of benzyl isothiocyanate towards cultured mammalian cells. ( Astley, SB; Edwards, SM; Hubert, RB; Johnson, IT; Musk, SR; Stephenson, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, KWW | 1 |
| Po, WW | 1 |
| Sohn, UD | 1 |
| Kim, HJ | 1 |
| Sakao, K | 1 |
| Vyas, AR | 1 |
| Chinni, SR | 1 |
| Amjad, AI | 1 |
| Parikh, R | 1 |
| Singh, SV | 2 |
| Basu, A | 1 |
| Haldar, S | 1 |
| Kim, SH | 1 |
| Liu, KC | 1 |
| Huang, YT | 1 |
| Wu, PP | 1 |
| Ji, BC | 1 |
| Yang, JS | 1 |
| Yang, JL | 1 |
| Chiu, TH | 1 |
| Chueh, FS | 1 |
| Chung, JG | 1 |
| Kuroiwa, Y | 1 |
| Nishikawa, A | 1 |
| Kitamura, Y | 1 |
| Kanki, K | 1 |
| Ishii, Y | 1 |
| Umemura, T | 1 |
| Hirose, M | 1 |
| Wattenberg, LW | 1 |
| Musk, SR | 2 |
| Astley, SB | 1 |
| Edwards, SM | 1 |
| Stephenson, P | 2 |
| Hubert, RB | 1 |
| Johnson, IT | 2 |
| Smith, TK | 1 |
| Stening, P | 1 |
| Fyfe, D | 1 |
| Kirlin, WG | 1 |
| Cai, J | 1 |
| Thompson, SA | 1 |
| Diaz, D | 1 |
| Kavanagh, TJ | 1 |
| Jones, DP | 1 |
10 other studies available for benzyl isothiocyanate and Adenocarcinoma
| Article | Year |
|---|---|
Benzyl Isothiocyanate Induces Apoptosis via Reactive Oxygen Species-Initiated Mitochondrial Dysfunction and DR4 and DR5 Death Receptor Activation in Gastric Adenocarcinoma Cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Biological Products; C | 2019 |
CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Cell Line, Tumor; Chemoprevention; Humans; Isothio | 2015 |
Anti-proliferative and proapoptotic effects of benzyl isothiocyanate on human pancreatic cancer cells is linked to death receptor activation and RasGAP/Rac1 down-modulation.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Prolifer | 2009 |
p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression.
Topics: Active Transport, Cell Nucleus; Adenocarcinoma; Animals; Apoptosis; Breast Neoplasms; Cell Line, Tum | 2010 |
The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
Topics: Acetylcysteine; Adenocarcinoma; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Caspase | 2011 |
Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinogenicity Tests; Carcinogens; Cell | 2006 |
Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Benz(a)Anthracenes; Cyanates; Di | 1981 |
Cytotoxic and clastogenic effects of benzyl isothiocyanate towards cultured mammalian cells.
Topics: Adenocarcinoma; Animals; Cell Survival; CHO Cells; Chromosome Aberrations; Colorectal Neoplasms; Cri | 1995 |
Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29.
Topics: Adenocarcinoma; Allyl Compounds; Anticarcinogenic Agents; Butyrates; Butyric Acid; Cell Differentiat | 1995 |
Glutathione redox potential in response to differentiation and enzyme inducers.
Topics: Adenocarcinoma; Butyrates; Cell Differentiation; Cell Size; Colonic Neoplasms; Enzyme Induction; Gen | 1999 |