benzyl alcohol has been researched along with Pain in 12 studies
Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
hydroxytoluene : Any member of the class of toluenes carrying one or more hydroxy substituents.
benzyl alcohol : An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.
aromatic alcohol : Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
aromatic primary alcohol : Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied its efficacy in decreasing the pain associated with IV administration of propofol and compared it with mixing lidocaine with propofol." | 9.11 | Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol. ( Minogue, SC; Sun, DA, 2005) |
| "9% sodium chloride containing the preservative benzyl alcohol with lidocaine hydrochloride 1% as an intradermal pretreatment for the relief of pain associated with intravenous cannulation." | 9.08 | Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain. ( McNelis, KA, 1998) |
| "Benzyl alcohol is reported to be painless on injection and to provide limited dermal anesthesia." | 9.07 | Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia. ( Howe, NR; Williams, JM, 1994) |
| " We studied its efficacy in decreasing the pain associated with IV administration of propofol and compared it with mixing lidocaine with propofol." | 5.11 | Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol. ( Minogue, SC; Sun, DA, 2005) |
| " The diphenhydramine median pain score was 55 mm, compared with 12." | 5.08 | Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia. ( Bartfield, JM; Jandreau, SW; Raccio-Robak, N, 1998) |
| "9% sodium chloride containing the preservative benzyl alcohol with lidocaine hydrochloride 1% as an intradermal pretreatment for the relief of pain associated with intravenous cannulation." | 5.08 | Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain. ( McNelis, KA, 1998) |
| "Benzyl alcohol is reported to be painless on injection and to provide limited dermal anesthesia." | 5.07 | Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia. ( Howe, NR; Williams, JM, 1994) |
| "Pain is similarly reduced for periocular botulinum toxin injections reconstituted with preserved saline compared with unpreserved saline." | 2.82 | Bacteriostatic preserved saline for pain-free periocular injections: review. ( Hunt, SV; Malhotra, R, 2022) |
| "The pain is caused mainly by the vehicle." | 2.67 | Analysis of the efficacy of measures to reduce pain after subcutaneous administration of epoetin alfa. ( Frenken, LA; Koene, RA; van Lier, HJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hunt, SV | 1 |
| Malhotra, R | 1 |
| Moses, A | 1 |
| Klager, S | 1 |
| Weinstein, A | 1 |
| Prabakaran, S | 1 |
| Sami, N | 1 |
| Weinstein, D | 1 |
| Belliveau, MJ | 1 |
| Jordan, DR | 1 |
| DUMONT, MM | 1 |
| Minogue, SC | 1 |
| Sun, DA | 1 |
| Thomas, DV | 2 |
| Frenken, LA | 1 |
| van Lier, HJ | 1 |
| Koene, RA | 1 |
| Williams, JM | 1 |
| Howe, NR | 1 |
| Bartfield, JM | 1 |
| Jandreau, SW | 1 |
| Raccio-Robak, N | 1 |
| McNelis, KA | 1 |
| Waite, DC | 1 |
| Jacobson, EW | 1 |
| Ennis, FA | 1 |
| Edelman, R | 1 |
| White, B | 1 |
| Kammer, R | 1 |
| Anderson, C | 1 |
| Kensil, CR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures[NCT05294640] | Phase 4 | 95 participants (Actual) | Interventional | 2022-05-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for benzyl alcohol and Pain
| Article | Year |
|---|---|
Bacteriostatic preserved saline for pain-free periocular injections: review.
Topics: Anesthetics, Local; Benzyl Alcohol; Botulinum Toxins, Type A; Double-Blind Method; Epinephrine; Huma | 2022 |
6 trials available for benzyl alcohol and Pain
| Article | Year |
|---|---|
Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol.
Topics: Adult; Anesthetics, Local; Bacteria; Benzyl Alcohol; Double-Blind Method; Female; Humans; Injections | 2005 |
Analysis of the efficacy of measures to reduce pain after subcutaneous administration of epoetin alfa.
Topics: Adult; Benzyl Alcohol; Benzyl Alcohols; Cross-Over Studies; Double-Blind Method; Erythropoietin; Fem | 1994 |
Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia.
Topics: Adult; Anesthetics; Benzyl Alcohol; Benzyl Alcohols; Double-Blind Method; Drug Combinations; Humans; | 1994 |
Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.
Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Diphenhydramine; Double-Blind Method; Drug Combinations; | 1998 |
Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain.
Topics: Adult; Aged; Anesthetics, Local; Benzyl Alcohol; Catheterization, Peripheral; Female; Humans; Inject | 1998 |
Three double-blind, randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS-21.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adjuvants, Immunologic; Adolescent; Adult; Aluminum Hydroxide; Be | 2001 |
5 other studies available for benzyl alcohol and Pain
| Article | Year |
|---|---|
A Comparative Analysis of Local Anesthetics: Injection Associated Pain and Duration of Anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Benzyl Alcohol; Double-Blind Method; Epinephrine; Humans; Lid | 2023 |
Minimizing injection pain.
Topics: Anesthetics, Local; Benzyl Alcohol; Drug Combinations; Eye Injuries, Penetrating; Humans; Injections | 2012 |
[THE TREATMENT OF BURNING GASTRIC PAINS AND PYROSIS IN PREGNANT WOMEN WITH BENZYL ALCOHOL].
Topics: Alcohols; Benzene; Benzyl Alcohol; Drug Therapy; Female; Heartburn; Humans; Pain; Pregnancy; Pregnan | 1965 |
Saline with benzyl alcohol prevents pain of needle insertion.
Topics: Anesthesia, Local; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Humans; Pain | 1984 |
Pain of skin infiltration with local anaesthetics.
Topics: Anesthetics, Local; Benzyl Alcohol; Benzyl Alcohols; Humans; Injections, Intradermal; Pain | 1985 |