Page last updated: 2024-10-16

benzyl alcohol and Kernicterus

benzyl alcohol has been researched along with Kernicterus in 5 studies

Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
hydroxytoluene : Any member of the class of toluenes carrying one or more hydroxy substituents.
benzyl alcohol : An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.
aromatic alcohol : Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
aromatic primary alcohol : Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.

Kernicterus: A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)

Research Excerpts

ExcerptRelevanceReference
"A prospective study in 1983 demonstrated no significant relationship between serum unbound bilirubin levels and kernicterus."7.71Benzyl alcohol, kernicterus, and unbound bilirubin. ( Ahlfors, CE, 2001)
"To determine the unbound bilirubin concentration (UBC) associated with kernicterus with the use of clinical data from clusters of kernicterus after sulfisoxazole and benzyl alcohol administration."7.70Unbound bilirubin associated with kernicterus: a historical approach. ( Ahlfors, CE, 2000)
"Benzyl alcohol was not used after June 10, 1982."5.28Risk factors associated with kernicterus in the newborn infant: importance of benzyl alcohol exposure. ( Ahdab-Barmada, M; Brown, DR; Cronin, CM, 1991)
"A prospective study in 1983 demonstrated no significant relationship between serum unbound bilirubin levels and kernicterus."3.71Benzyl alcohol, kernicterus, and unbound bilirubin. ( Ahlfors, CE, 2001)
"To determine the unbound bilirubin concentration (UBC) associated with kernicterus with the use of clinical data from clusters of kernicterus after sulfisoxazole and benzyl alcohol administration."3.70Unbound bilirubin associated with kernicterus: a historical approach. ( Ahlfors, CE, 2000)
"Benzyl alcohol was not used after June 10, 1982."1.28Risk factors associated with kernicterus in the newborn infant: importance of benzyl alcohol exposure. ( Ahdab-Barmada, M; Brown, DR; Cronin, CM, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wennberg, RP1
Ahlfors, CE3
Cronin, CM1
Brown, DR1
Ahdab-Barmada, M1
Jardine, DS1
Rogers, K1

Other Studies

5 other studies available for benzyl alcohol and Kernicterus

ArticleYear
A different view on bilirubin binding.
    Pediatrics, 2006, Volume: 118, Issue:2

    Topics: Benzyl Alcohol; Bilirubin; Binding Sites; Blood Chemical Analysis; Blood Proteins; Humans; Hyperbili

2006
Unbound bilirubin associated with kernicterus: a historical approach.
    The Journal of pediatrics, 2000, Volume: 137, Issue:4

    Topics: Benzyl Alcohol; Bilirubin; Humans; Infant, Newborn; Kernicterus; Sulfisoxazole

2000
Benzyl alcohol, kernicterus, and unbound bilirubin.
    The Journal of pediatrics, 2001, Volume: 139, Issue:2

    Topics: Anesthetics, Local; Benzyl Alcohol; Bilirubin; Humans; Infant, Newborn; Kernicterus; Prospective Stu

2001
Risk factors associated with kernicterus in the newborn infant: importance of benzyl alcohol exposure.
    American journal of perinatology, 1991, Volume: 8, Issue:2

    Topics: Analysis of Variance; Benzyl Alcohol; Benzyl Alcohols; Bilirubin; Birth Weight; Case-Control Studies

1991
Relationship of benzyl alcohol to kernicterus, intraventricular hemorrhage, and mortality in preterm infants.
    Pediatrics, 1989, Volume: 83, Issue:2

    Topics: Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Cerebral Hemorrhage; Cerebral Ventricles; Cohort

1989