benzyl alcohol has been researched along with Acute Liver Injury, Drug-Induced in 6 studies
Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
hydroxytoluene : Any member of the class of toluenes carrying one or more hydroxy substituents.
benzyl alcohol : An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.
aromatic alcohol : Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
aromatic primary alcohol : Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Considering its toxic effect and the loss of protection in PHH, BA is not a clinically useful treatment option for APAP overdose patient." | 1.42 | Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. ( Du, K; Jaeschke, H; McGill, MR; Xie, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, C | 2 |
| Huang, H | 1 |
| Whelan, S | 1 |
| Liu, L | 1 |
| Kautza, B | 1 |
| Luciano, J | 1 |
| Wang, G | 1 |
| Chen, G | 1 |
| Stratimirovic, S | 1 |
| Tsung, A | 1 |
| Billiar, TR | 2 |
| Zuckerbraun, BS | 2 |
| Patman, G | 1 |
| Jaeschke, H | 2 |
| Du, K | 2 |
| McGill, MR | 1 |
| Xie, Y | 1 |
| Cebula, TA | 1 |
| El-Hage, AN | 1 |
| Ferrans, VJ | 1 |
6 other studies available for benzyl alcohol and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzyl Alcohol; Cells, Cultured; Chemical and Drug | 2014 |
Liver: benzyl alcohol limits acute liver injury.
Topics: Acetaminophen; Animals; Benzyl Alcohol; Chemical and Drug Induced Liver Injury; Mice; Toll-Like Rece | 2014 |
Reply: To PMID 24798499.
Topics: Animals; Benzyl Alcohol; Chemical and Drug Induced Liver Injury; Male; Toll-Like Receptor 4 | 2015 |
Benzyl Alcohol: A novel treatment for acetaminophen overdose?
Topics: Animals; Benzyl Alcohol; Chemical and Drug Induced Liver Injury; Male; Toll-Like Receptor 4 | 2015 |
Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Benzyl Alcohol; Chemical and D | 2015 |
Toxic interactions of benzyl alcohol with bacterial endotoxin.
Topics: Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Blood Chemical Analysis; Chemical and Dr | 1984 |