Page last updated: 2024-10-16

benzyl alcohol and Ache

benzyl alcohol has been researched along with Ache in 12 studies

Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
hydroxytoluene : Any member of the class of toluenes carrying one or more hydroxy substituents.
benzyl alcohol : An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.
aromatic alcohol : Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
aromatic primary alcohol : Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.

Research Excerpts

ExcerptRelevanceReference
" We studied its efficacy in decreasing the pain associated with IV administration of propofol and compared it with mixing lidocaine with propofol."9.11Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol. ( Minogue, SC; Sun, DA, 2005)
"9% sodium chloride containing the preservative benzyl alcohol with lidocaine hydrochloride 1% as an intradermal pretreatment for the relief of pain associated with intravenous cannulation."9.08Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain. ( McNelis, KA, 1998)
"Benzyl alcohol is reported to be painless on injection and to provide limited dermal anesthesia."9.07Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia. ( Howe, NR; Williams, JM, 1994)
" We studied its efficacy in decreasing the pain associated with IV administration of propofol and compared it with mixing lidocaine with propofol."5.11Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol. ( Minogue, SC; Sun, DA, 2005)
" The diphenhydramine median pain score was 55 mm, compared with 12."5.08Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia. ( Bartfield, JM; Jandreau, SW; Raccio-Robak, N, 1998)
"9% sodium chloride containing the preservative benzyl alcohol with lidocaine hydrochloride 1% as an intradermal pretreatment for the relief of pain associated with intravenous cannulation."5.08Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain. ( McNelis, KA, 1998)
"Benzyl alcohol is reported to be painless on injection and to provide limited dermal anesthesia."5.07Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia. ( Howe, NR; Williams, JM, 1994)
"Pain is similarly reduced for periocular botulinum toxin injections reconstituted with preserved saline compared with unpreserved saline."2.82Bacteriostatic preserved saline for pain-free periocular injections: review. ( Hunt, SV; Malhotra, R, 2022)
"The pain is caused mainly by the vehicle."2.67Analysis of the efficacy of measures to reduce pain after subcutaneous administration of epoetin alfa. ( Frenken, LA; Koene, RA; van Lier, HJ, 1994)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Hunt, SV1
Malhotra, R1
Moses, A1
Klager, S1
Weinstein, A1
Prabakaran, S1
Sami, N1
Weinstein, D1
Belliveau, MJ1
Jordan, DR1
DUMONT, MM1
Minogue, SC1
Sun, DA1
Thomas, DV2
Frenken, LA1
van Lier, HJ1
Koene, RA1
Williams, JM1
Howe, NR1
Bartfield, JM1
Jandreau, SW1
Raccio-Robak, N1
McNelis, KA1
Waite, DC1
Jacobson, EW1
Ennis, FA1
Edelman, R1
White, B1
Kammer, R1
Anderson, C1
Kensil, CR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures[NCT05294640]Phase 495 participants (Actual)Interventional2022-05-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for benzyl alcohol and Ache

ArticleYear
Bacteriostatic preserved saline for pain-free periocular injections: review.
    Eye (London, England), 2022, Volume: 36, Issue:8

    Topics: Anesthetics, Local; Benzyl Alcohol; Botulinum Toxins, Type A; Double-Blind Method; Epinephrine; Huma

2022

Trials

6 trials available for benzyl alcohol and Ache

ArticleYear
Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:3

    Topics: Adult; Anesthetics, Local; Bacteria; Benzyl Alcohol; Double-Blind Method; Female; Humans; Injections

2005
Analysis of the efficacy of measures to reduce pain after subcutaneous administration of epoetin alfa.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:9

    Topics: Adult; Benzyl Alcohol; Benzyl Alcohols; Cross-Over Studies; Double-Blind Method; Erythropoietin; Fem

1994
Benzyl alcohol attenuates the pain of lidocaine injections and prolongs anesthesia.
    The Journal of dermatologic surgery and oncology, 1994, Volume: 20, Issue:11

    Topics: Adult; Anesthetics; Benzyl Alcohol; Benzyl Alcohols; Double-Blind Method; Drug Combinations; Humans;

1994
Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.
    Annals of emergency medicine, 1998, Volume: 32, Issue:6

    Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Diphenhydramine; Double-Blind Method; Drug Combinations;

1998
Intradermal bacteriostatic 0.9% sodium chloride containing the preservative benzyl alcohol compared with intradermal lidocaine hydrochloride 1% for attenuation of intravenous cannulation pain.
    AANA journal, 1998, Volume: 66, Issue:6

    Topics: Adult; Aged; Anesthetics, Local; Benzyl Alcohol; Catheterization, Peripheral; Female; Humans; Inject

1998
Three double-blind, randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS-21.
    Vaccine, 2001, Jul-16, Volume: 19, Issue:28-29

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adjuvants, Immunologic; Adolescent; Adult; Aluminum Hydroxide; Be

2001

Other Studies

5 other studies available for benzyl alcohol and Ache

ArticleYear
A Comparative Analysis of Local Anesthetics: Injection Associated Pain and Duration of Anesthesia.
    Journal of drugs in dermatology : JDD, 2023, Apr-01, Volume: 22, Issue:4

    Topics: Anesthesia, Local; Anesthetics, Local; Benzyl Alcohol; Double-Blind Method; Epinephrine; Humans; Lid

2023
Minimizing injection pain.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2012, Oct-16, Volume: 184, Issue:15

    Topics: Anesthetics, Local; Benzyl Alcohol; Drug Combinations; Eye Injuries, Penetrating; Humans; Injections

2012
[THE TREATMENT OF BURNING GASTRIC PAINS AND PYROSIS IN PREGNANT WOMEN WITH BENZYL ALCOHOL].
    Journal de medecine de Lyon, 1965, Jan-20, Volume: 46

    Topics: Alcohols; Benzene; Benzyl Alcohol; Drug Therapy; Female; Heartburn; Humans; Pain; Pregnancy; Pregnan

1965
Saline with benzyl alcohol prevents pain of needle insertion.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:9

    Topics: Anesthesia, Local; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Humans; Pain

1984
Pain of skin infiltration with local anaesthetics.
    Anaesthesia and intensive care, 1985, Volume: 13, Issue:1

    Topics: Anesthetics, Local; Benzyl Alcohol; Benzyl Alcohols; Humans; Injections, Intradermal; Pain

1985