Page last updated: 2024-08-18

benzothiophene and Breast Neoplasms

benzothiophene has been researched along with Breast Neoplasms in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (11.11)	29.6817
2010's	5 (55.56)	24.3611
2020's	3 (33.33)	2.80

Authors

Authors	Studies
Bai, C; Dong, H; Hao, H; Li, Z; Luo, G; Lv, Y; Qi, L; Ren, S; Shen, H; Wu, S; Xiang, H; Xiao, Y; Xiong, S; Ye, H; Zhu, M; Zhu, Y	1
Barbarossa, A; Caruso, A; Ceramella, J; Dallemagne, P; El-Kashef, H; Grande, F; Iacopetta, D; Occhiuzzi, MA; Rault, S; Rizzuti, B; Saturnino, C; Sinicropi, MS	1
Chen, H; Dubrovyskyii, O; Dye, K; Gordon-Blake, J; Gutgesell, LM; He, D; Hollas, M; Huang, F; Lasek, AW; Lee, S; Li, Y; Lu, Y; Rosales, CI; Shen, Z; Thatcher, GRJ; Tonetti, DA; Wang, Y; Xiong, R; Zhao, H; Zhao, J	1
Barakat, A; Boraei, ATA; Eltamany, EH; Gad, EM; Hammad, MSAG; Nafie, MS	1
Bai, C; Luo, G; Ren, S; Wu, S; Xiang, H; Zhu, M	1
Cherkasov, A; Dalal, K; Lallous, N; Munuganti, RSN; Rennie, PS; Sharma, A; Singh, K; Yamazaki, T; Yoon, JS	1
Gherezghiher, T; Jordan, VC; Maximov, PY; Michalsen, BT; Molloy, ME; Patel, H; Thatcher, GR; Tonetti, DA; White, BE; Xiong, R; Zhao, H	1
Gutgesell, LM; Karumudi, B; Lee, S; Lu, Y; Thatcher, GR; Tonetti, DA; Wang, Y; Xiong, R; Zhao, H; Zhao, J	1
Cooperwood, JS; Khan, MO; Musa, MA	1

Reviews

1 review(s) available for benzothiophene and Breast Neoplasms

Article	Year
Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs). Current medicinal chemistry, 2007, Volume: 14, Issue:11 Topics: Breast Neoplasms; Drug Design; Estrogen Receptor alpha; Female; Humans; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stilbenes; Structure-Activity Relationship; Tamoxifen; Thiophenes; Toremifene	2007

Article

Year

Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs).

Current medicinal chemistry, 2007, Volume: 14, Issue:11

Topics: Breast Neoplasms; Drug Design; Estrogen Receptor alpha; Female; Humans; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stilbenes; Structure-Activity Relationship; Tamoxifen; Thiophenes; Toremifene

2007

Other Studies

8 other study(ies) available for benzothiophene and Breast Neoplasms

Article	Year
X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles. Bioorganic chemistry, 2023, Volume: 141 Topics: Animals; Breast Neoplasms; Crystallography, X-Ray; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Female; Humans; MCF-7 Cells; Mice; Receptors, Estrogen	2023
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization. European journal of medicinal chemistry, 2019, Nov-01, Volume: 181 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Design; Female; Humans; Molecular Docking Simulation; Quinazolinones; Thiophenes; Topoisomerase I Inhibitors; Tubulin; Tubulin Modulators	2019
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer. Journal of medicinal chemistry, 2019, 12-26, Volume: 62, Issue:24 Topics: Animals; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Mutation; Proteolysis; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Thiophenes; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2019
Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[ Molecules (Basel, Switzerland), 2020, May-28, Volume: 25, Issue:11 Topics: Alkylation; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Hep G2 Cells; Humans; MCF-7 Cells; Pyrimidinones; Structure-Activity Relationship; Thiophenes	2020
Design and synthesis of novel benzothiophene analogs as selective estrogen receptor covalent antagonists against breast cancer. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Estrogen Receptor Antagonists; Female; Humans; MCF-7 Cells; Molecular Structure; Receptors, Estrogen; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured	2021
Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers. International journal of molecular sciences, 2018, Feb-15, Volume: 19, Issue:2 Topics: Binding Sites; Breast Neoplasms; Cell Proliferation; Chromatin; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mutation; Protein Binding; Tamoxifen; Thiophenes	2018
Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer. Molecular cancer therapeutics, 2014, Volume: 13, Issue:11 Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression; Estrogens; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; Random Allocation; Receptors, Estrogen; Tamoxifen; Thiophenes; Transfection; Xenograft Model Antitumor Assays	2014
Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer. Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4 Topics: Animals; Antineoplastic Agents, Hormonal; Breast; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Mice, Nude; Models, Molecular; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Thiophenes	2017