benzothiazole has been researched along with Alzheimer Disease in 19 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (21.05) | 29.6817 |
2010's | 13 (68.42) | 24.3611 |
2020's | 2 (10.53) | 2.80 |
Authors | Studies |
---|---|
Anderl-Straub, S; Beer, AJ; Bohn, P; Fissler, P; Glatting, G; Higuchi, M; Kletting, P; Kneer, K; Ludolph, A; Otto, M; Polivka, D; Riepe, MW; Solbach, C; Strobel, J; von Arnim, CAF; Winter, G; Yousefzadeh-Nowshahr, E | 1 |
Berg, KR; Cifelli, JL; Yang, J | 1 |
Ågren, H; Arul Murugan, N; Zaleśny, R | 1 |
Cardoso, SM; Chaves, S; Marques, SM; Nunes, A; Quintanova, C; Santos, MA; Silva, DF | 1 |
Bergfors, A; Gillberg, PG; Marutle, A; Ni, R; Nordberg, A | 1 |
Cardoso, SM; Esteves, AR; Keri, RS; Marques, SM; Quintanova, C; Santos, MA | 1 |
Aitken, L; Benek, O; Dolezal, M; Gunn-Moore, F; Hroch, L; Kuca, K; Musilek, K | 1 |
Cui, M; Dai, J; Jia, J; Liu, B | 1 |
Adams, DL; Stefansson, S; Tang, CM | 1 |
Chung, TS; Cifelli, JL; Liu, H; Mayer, M; Prangkio, P; Yang, J | 1 |
Aitken, L; Benek, O; Dohnal, V; Dolezal, R; Guest, P; Gunn-Moore, F; Hroch, L; Janockova, J; Kuca, K; Musil, K; Musilek, K; Smith, TK; Soukup, O | 1 |
Borghgraef, P; Bormans, G; Cleynhens, J; Kung, H; Serdons, K; Van Leuven, F; Vanderghinste, D; Verbruggen, A; Verduyckt, T | 1 |
Borghgraef, P; Bormans, G; Cleynhens, J; Kung, H; Serdons, K; Terwinghe, C; Van Laere, K; Van Leuven, F; Vanderghinste, D; Verbruggen, A; Verduyckt, T; Vermaelen, P | 1 |
Alagille, D; Baldwin, RM; DaCosta, H; Tamagnan, GD | 1 |
Cisek, K; Honson, NS; Jensen, JR; Kuret, J | 1 |
Bergh, M; Jeppsson, F; Johnström, P; Juréus, A; Neelissen, J; Pyring, D; Sandell, J; Schou, M; Svensson, S; Swahn, BM | 1 |
Can, OD; Ozkay, UD; Ozkay, Y; Oztürk, Y | 1 |
Debnath, ML; Holt, DP; Huang, GF; Klunk, WE; Mathis, CA; Shao, L; Wang, Y | 1 |
LeVine, H | 1 |
1 review(s) available for benzothiazole and Alzheimer Disease
Article | Year |
---|---|
Benzothiazoles - scaffold of interest for CNS targeted drugs.
Topics: Alzheimer Disease; Animals; Anticonvulsants; Benzothiazoles; Humans; Neuroprotective Agents; Quantitative Structure-Activity Relationship; Radionuclide Imaging | 2015 |
18 other study(ies) available for benzothiazole and Alzheimer Disease
Article | Year |
---|---|
Quantitative analysis of regional distribution of tau pathology with 11C-PBB3-PET in a clinical setting.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Biomarkers; Brain; Carbon Radioisotopes; Humans; Positron-Emission Tomography; tau Proteins | 2022 |
Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons.
Topics: Alzheimer Disease; Benzothiazoles; Brain; Cells, Cultured; Cognitive Dysfunction; Dendritic Spines; Disks Large Homolog 4 Protein; Hippocampus; Humans; Induced Pluripotent Stem Cells; Neurodegenerative Diseases; Neurons; ras-GRF1; Synapses | 2020 |
Unusual binding-site-specific photophysical properties of a benzothiazole-based optical probe in amyloid beta fibrils.
Topics: Alzheimer Disease; Amyloid; Benzothiazoles; Binding Sites; Fluorescent Dyes; Humans; Molecular Docking Simulation; Protein Binding; Quantum Theory; Thermodynamics | 2018 |
Multifunctional iron-chelators with protective roles against neurodegenerative diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Half-Life; Humans; Iron Chelating Agents; Molecular Docking Simulation; Peptide Fragments; Protein Structure, Tertiary; Pyridones; Zinc | 2013 |
Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Aniline Compounds; Apolipoprotein E4; Benzothiazoles; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Peptide Fragments; Postmortem Changes; Radionuclide Imaging; Thiazoles; Tissue Distribution; Tritium | 2013 |
Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Benzothiazoles; Cell Line; Cholinesterase Inhibitors; Drug Design; Humans; Models, Molecular; Neuroprotective Agents; Structure-Activity Relationship; Tacrine | 2013 |
99mTc(CO)3-Labeled Benzothiazole Derivatives Preferentially Bind Cerebrovascular Amyloid: Potential Use as Imaging Agents for Cerebral Amyloid Angiopathy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Benzothiazoles; Brain; Cerebral Amyloid Angiopathy; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Plaque, Amyloid; Radiopharmaceuticals; Technetium Compounds; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2015 |
Common benzothiazole and benzoxazole fluorescent DNA intercalators for studying Alzheimer Aβ1-42 and prion amyloid peptides.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Benzoxazoles; Congo Red; Fluorescent Dyes; Humans; Intercalating Agents; Peptide Fragments; Prions | 2012 |
Benzothiazole Amphiphiles Ameliorate Amyloid β-Related Cell Toxicity and Oxidative Stress.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidosis; Benzothiazoles; Cell Line, Tumor; Cell Survival; Humans; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species | 2016 |
Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Alzheimer Disease; Animals; Benzothiazoles; Cell Survival; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Molecular Structure; Structure-Activity Relationship; Urea | 2016 |
11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid beta in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Brain; Carbon Radioisotopes; Fluorine Radioisotopes; Humans; Hydroxides; Isomerism; Mice; Radioactive Tracers; Staining and Labeling; Thiazoles | 2009 |
Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Chemistry, Pharmaceutical; Drug Design; Fluorine Radioisotopes; Humans; Kinetics; Mice; Mice, Transgenic; Models, Chemical; Temperature; Tissue Distribution | 2009 |
2-Arylimidazo[2,1-b]benzothiazoles: a new family of amyloid binding agents with potential for PET and SPECT imaging of Alzheimer's brain.
Topics: Alzheimer Disease; Amyloid; Benzothiazoles; Binding, Competitive; Biological Assay; Humans; Imidazoles; Positron-Emission Tomography; Protein Binding; Tomography, Emission-Computed, Single-Photon | 2011 |
Ligand polarizability contributes to tau fibril binding affinity.
Topics: Alzheimer Disease; Benzothiazoles; Binding Sites; Humans; Indoles; Ligands; Oxindoles; Phenothiazines; Protein Binding; tau Proteins; Thiazoles | 2011 |
Synthesis and evaluation of pyridylbenzofuran, pyridylbenzothiazole and pyridylbenzoxazole derivatives as ¹⁸F-PET imaging agents for β-amyloid plaques.
Topics: Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Animals; Benzofurans; Benzothiazoles; Benzoxazoles; Brain; Contrast Media; Fluorine Radioisotopes; Humans; Mice; Mice, Transgenic; Positron-Emission Tomography; Radiopharmaceuticals; Structure-Activity Relationship | 2012 |
Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Benzothiazoles; Cognition Disorders; Disease Models, Animal; Maze Learning; Memory; Motor Activity; Piperazines; Rats; Rats, Wistar; Streptozocin | 2012 |
Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Binding, Competitive; Brain; Carbon Radioisotopes; Cerebellum; Disease Models, Animal; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Transgenic; Molecular Structure; Plaque, Amyloid; Positron-Emission Tomography; Radioligand Assay; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2004 |
Multiple ligand binding sites on A beta(1-40) fibrils.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Binding Sites; Congo Red; Fluorescent Dyes; Humans; Ibuprofen; Ligands; Models, Chemical; Molecular Structure; Naproxen; Peptide Fragments; Protein Binding; Thiazoles | 2005 |