benzothiazide has been researched along with Tuberculosis in 28 studies
benzothiazide: structure
benzthiazide : 7-Sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by chlorine and that at position 3 is substituted by a benzylsulfanylmethyl group. A diuretic, it is used to treat hypertension and edema.
Tuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.
Excerpt | Relevance | Reference |
---|---|---|
"We show that treatment of M." | 5.42 | The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. ( Abramovitch, RB; Champion, PA; Colvin, CJ; Johnson, BK; Mba Medie, F; Needle, DB, 2015) |
"Mycobacterium tuberculosis is one of the worlds' most successful and sophisticated pathogens." | 2.44 | Not to wake a sleeping giant: new insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection. ( Lin, MY; Ottenhoff, TH, 2008) |
"We show that treatment of M." | 1.42 | The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. ( Abramovitch, RB; Champion, PA; Colvin, CJ; Johnson, BK; Mba Medie, F; Needle, DB, 2015) |
"Mycobacterium tuberculosis is the causative agent of tuberculosis, killing millions of people every year." | 1.40 | The copper-responsive RicR regulon contributes to Mycobacterium tuberculosis virulence. ( Butler-Wu, S; Darwin, KH; Festa, RA; Ioerger, TR; Sacchettini, JC; Samanovic, MI; Shi, X, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 10 (35.71) | 29.6817 |
2010's | 16 (57.14) | 24.3611 |
2020's | 2 (7.14) | 2.80 |
Authors | Studies |
---|---|
Saini, V | 1 |
Chinta, KC | 1 |
Reddy, VP | 1 |
Glasgow, JN | 1 |
Stein, A | 1 |
Lamprecht, DA | 1 |
Rahman, MA | 1 |
Mackenzie, JS | 1 |
Truebody, BE | 1 |
Adamson, JH | 1 |
Kunota, TTR | 1 |
Bailey, SM | 1 |
Moellering, DR | 1 |
Lancaster, JR | 1 |
Steyn, AJC | 1 |
Shanmuga Priya, VG | 1 |
Bhandare, V | 1 |
Muddapur, UM | 1 |
Swaminathan, P | 1 |
Fandilolu, PM | 1 |
Sonawane, KD | 1 |
Pandey, K | 1 |
Singh, S | 2 |
Bhatt, P | 1 |
Sharma, M | 1 |
Chaudhry, A | 1 |
Sharma, S | 2 |
Gaudion, A | 1 |
Dawson, L | 1 |
Davis, E | 1 |
Smollett, K | 1 |
Saraav, I | 1 |
Shi, X | 1 |
Festa, RA | 1 |
Ioerger, TR | 1 |
Butler-Wu, S | 1 |
Sacchettini, JC | 1 |
Darwin, KH | 1 |
Samanovic, MI | 1 |
Rustad, TR | 1 |
Minch, KJ | 1 |
Ma, S | 1 |
Winkler, JK | 1 |
Hobbs, S | 1 |
Hickey, M | 1 |
Brabant, W | 1 |
Turkarslan, S | 1 |
Price, ND | 1 |
Baliga, NS | 1 |
Sherman, DR | 2 |
Mehra, S | 3 |
Foreman, TW | 2 |
Didier, PJ | 1 |
Ahsan, MH | 1 |
Hudock, TA | 2 |
Kissee, R | 1 |
Golden, NA | 2 |
Gautam, US | 3 |
Johnson, AM | 1 |
Alvarez, X | 2 |
Russell-Lodrigue, KE | 1 |
Doyle, LA | 1 |
Roy, CJ | 1 |
Niu, T | 2 |
Blanchard, JL | 1 |
Khader, SA | 1 |
Lackner, AA | 2 |
Kaushal, D | 3 |
Voskuil, MI | 3 |
Schlesinger, LS | 1 |
Johnson, BK | 1 |
Colvin, CJ | 1 |
Needle, DB | 1 |
Mba Medie, F | 1 |
Champion, PA | 1 |
Abramovitch, RB | 1 |
Veatch, AV | 2 |
Caskey, J | 1 |
McGillivray, A | 1 |
Subramanian, R | 1 |
Kousoulas, KG | 1 |
Domenech, P | 1 |
Zou, J | 1 |
Averback, A | 1 |
Syed, N | 1 |
Curtis, D | 1 |
Donato, S | 1 |
Reed, MB | 2 |
Bandyopadhyay, N | 1 |
LoBato, DN | 1 |
Gentry, KM | 1 |
Cavigli, A | 1 |
Mueller, M | 1 |
Hwang, SA | 1 |
Hunter, RL | 1 |
Bader, JS | 1 |
Lin, MY | 3 |
Ottenhoff, TH | 4 |
Black, GF | 1 |
Thiel, BA | 1 |
Ota, MO | 1 |
Parida, SK | 1 |
Adegbola, R | 1 |
Boom, WH | 1 |
Dockrell, HM | 2 |
Franken, KL | 3 |
Friggen, AH | 2 |
Hill, PC | 1 |
Klein, MR | 4 |
Lalor, MK | 1 |
Mayanja, H | 1 |
Schoolnik, G | 1 |
Stanley, K | 1 |
Weldingh, K | 1 |
Kaufmann, SH | 1 |
Walzl, G | 1 |
Bartek, IL | 1 |
Rutherford, R | 1 |
Gruppo, V | 1 |
Morton, RA | 1 |
Morris, RP | 1 |
Visconti, KC | 1 |
Ryan, GJ | 1 |
Schoolnik, GK | 2 |
Lenaerts, A | 1 |
Majumdar, SD | 1 |
Sharma, D | 1 |
Vashist, A | 1 |
Kaur, K | 1 |
Taneja, NK | 1 |
Chauhan, S | 1 |
Challu, VK | 1 |
Ramanathan, VD | 1 |
Balasangameshwara, V | 1 |
Kumar, P | 1 |
Tyagi, JS | 1 |
Flores Valdez, MA | 1 |
Isaza, JP | 1 |
Duque, C | 1 |
Gomez, V | 1 |
Robledo, J | 1 |
Barrera, LF | 1 |
Alzate, JF | 1 |
Lee, JH | 1 |
Ammerman, NC | 1 |
Nolan, S | 1 |
Geiman, DE | 1 |
Lun, S | 1 |
Guo, H | 1 |
Bishai, WR | 2 |
Hegde, SR | 1 |
Rajasingh, H | 1 |
Das, C | 1 |
Mande, SS | 1 |
Mande, SC | 1 |
Parish, T | 1 |
Smith, DA | 1 |
Roberts, G | 1 |
Betts, J | 1 |
Stoker, NG | 1 |
Ohno, H | 1 |
Zhu, G | 1 |
Mohan, VP | 1 |
Chu, D | 1 |
Kohno, S | 1 |
Jacobs, WR | 1 |
Chan, J | 1 |
Sun, R | 1 |
Converse, PJ | 1 |
Ko, C | 1 |
Tyagi, S | 1 |
Morrison, NE | 1 |
Roupie, V | 1 |
Romano, M | 1 |
Zhang, L | 1 |
Korf, H | 1 |
Huygen, K | 2 |
Gagneux, S | 1 |
Deriemer, K | 1 |
Small, PM | 1 |
Barry, CE | 1 |
Geluk, A | 1 |
Smith, SG | 1 |
Stewart, AL | 1 |
Verduyn, MJ | 1 |
van Meijgaarden, KE | 1 |
Shiloh, MU | 1 |
Manzanillo, P | 1 |
Cox, JS | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Characterization of Immune Responses in Treatment-induced Latency in Pulmonary Tuberculosis[NCT01154959] | Phase 3 | 120 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for benzothiazide and Tuberculosis
Article | Year |
---|---|
Immunogenic potential of latency associated antigens against Mycobacterium tuberculosis.
Topics: Animals; Antigens, Bacterial; Bacterial Proteins; DNA-Binding Proteins; Humans; Latent Tuberculosis; | 2014 |
Not to wake a sleeping giant: new insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection.
Topics: Animals; Antitubercular Agents; Genome; Host-Pathogen Interactions; Humans; Immunity, Cellular; Myco | 2008 |
26 other studies available for benzothiazide and Tuberculosis
Article | Year |
---|---|
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.
Topics: Animals; Copper; Cystathionine beta-Synthase; Cytokines; Disease Models, Animal; Electron Transport | 2020 |
Molecular modeling approach to identify inhibitors of Rv2004c (rough morphology and virulent strain gene), a DosR (dormancy survival regulator) regulon protein from
Topics: Bacterial Proteins; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Mycobacteri | 2022 |
DosR proteins of Mycobacterium tuberculosis upregulate effector T cells and down regulate T regulatory cells in TB patients and their healthy contacts.
Topics: Antigens, Bacterial; Bacterial Proteins; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyt | 2019 |
Characterisation of the Mycobacterium tuberculosis alternative sigma factor SigG: its operon and regulon.
Topics: Animals; Base Sequence; Cells, Cultured; DNA Damage; Female; Gene Expression Profiling; Gene Express | 2013 |
The copper-responsive RicR regulon contributes to Mycobacterium tuberculosis virulence.
Topics: Animals; Copper; Disease Models, Animal; Female; Gene Expression Regulation, Bacterial; Gene Knockou | 2014 |
Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network.
Topics: Cloning, Molecular; Gene Expression Regulation, Bacterial; Gene Regulatory Networks; Humans; Isoniaz | 2014 |
The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence.
Topics: Animals; Bacterial Proteins; Disease Models, Animal; DNA-Binding Proteins; Hypoxia; Macaca mulatta; | 2015 |
Toward Resolving the Paradox of the Critical Role of the DosR Regulon in Mycobacterium tuberculosis Persistence and Active Disease.
Topics: Animals; Bacterial Proteins; Hypoxia; Mycobacterium tuberculosis; Protein Kinases; Regulon; Tubercul | 2015 |
The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence.
Topics: Animals; Antigens, Bacterial; Bacterial Proteins; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases | 2015 |
Sequencing-relative to hybridization-based transcriptomics approaches better define Mycobacterium tuberculosis stress-response regulons.
Topics: Bacterial Proteins; Diamide; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regula | 2016 |
Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis.
Topics: Animals; Bacterial Proteins; Beijing; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; L | 2017 |
Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis.
Topics: Anaerobiosis; Animals; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bact | 2017 |
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.
Topics: Adolescent; Adult; Aged; Antigens, Bacterial; Bacterial Proteins; Cells, Cultured; Child; DNA-Bindin | 2009 |
The DosR regulon of M. tuberculosis and antibacterial tolerance.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Disease Models, Animal; DNA-Binding Proteins; Dr | 2009 |
Co-expression of DevR and DevR(N)-Aph proteins is associated with hypoxic adaptation defect and virulence attenuation of Mycobacterium tuberculosis.
Topics: Adaptation, Physiological; Anaerobiosis; Animals; Bacterial Proteins; Cell Line; Gene Expression Reg | 2010 |
DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions.
Topics: BCG Vaccine; Gene Expression Regulation, Bacterial; Humans; Lymphocyte Activation; Mycobacterium tub | 2010 |
Whole genome shotgun sequencing of one Colombian clinical isolate of Mycobacterium tuberculosis reveals DosR regulon gene deletions.
Topics: Adult; Bacterial Proteins; Colombia; DNA-Binding Proteins; Gene Deletion; Genes, Bacterial; Genome, | 2012 |
Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Multiple, Bacterial; | 2012 |
Understanding communication signals during mycobacterial latency through predicted genome-wide protein interactions and boolean modeling.
Topics: Cell Communication; Computational Biology; Gene Regulatory Networks; Genome, Bacterial; Latent Tuber | 2012 |
The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence.
Topics: Animals; Bacterial Proteins; Cell Line; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, | 2003 |
The effects of reactive nitrogen intermediates on gene expression in Mycobacterium tuberculosis.
Topics: Animals; Female; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Hypoxia; | 2003 |
Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set.
Topics: Animals; Bacterial Proteins; Cell Line; Colony Count, Microbial; Consensus Sequence; Disease Models, | 2004 |
Immunogenicity of eight dormancy regulon-encoded proteins of Mycobacterium tuberculosis in DNA-vaccinated and tuberculosis-infected mice.
Topics: Animals; Antibodies, Bacterial; Antigens, Bacterial; Epitope Mapping; Epitopes, B-Lymphocyte; Epitop | 2007 |
The W-Beijing lineage of Mycobacterium tuberculosis overproduces triglycerides and has the DosR dormancy regulon constitutively upregulated.
Topics: Animals; China; DNA Primers; Gene Expression Regulation, Bacterial; Glycolipids; Humans; Mice; Mycob | 2007 |
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination.
Topics: Adolescent; Adult; Animals; Antigens, Bacterial; Bacterial Proteins; BCG Vaccine; Cattle; Female; Hu | 2007 |
Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection.
Topics: Animals; Carbon Monoxide; Cells, Cultured; Gene Expression Regulation, Bacterial; Heme Oxygenase-1; | 2008 |