Page last updated: 2024-08-18

benzonitrile and Parkinson Disease

benzonitrile has been researched along with Parkinson Disease in 1 studies

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Berger, Z; Chen, Y; Coffman, KJ; Galatsis, P; Hayward, MM; Henderson, JL; Hirst, WD; Houle, C; Jasti, J; Kormos, BL; Kurumbail, RG; Needle, E; Noell, GS; Steyn, SJ; Verhoest, PR; Wager, TT	1

Other Studies

1 other study(ies) available for benzonitrile and Parkinson Disease

Article	Year
Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. Journal of medicinal chemistry, 2015, Jan-08, Volume: 58, Issue:1 Topics: Amino Acid Sequence; Animals; Area Under Curve; Brain; Crystallography, X-Ray; Drug Discovery; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation, Missense; Nitriles; Parkinson Disease; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteome; Pyrimidines; Pyrroles; Rats	2015

Article

Year

Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor.

Journal of medicinal chemistry, 2015, Jan-08, Volume: 58, Issue:1

Topics: Amino Acid Sequence; Animals; Area Under Curve; Brain; Crystallography, X-Ray; Drug Discovery; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation, Missense; Nitriles; Parkinson Disease; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteome; Pyrimidines; Pyrroles; Rats

2015