benzonidazole has been researched along with Inflammation in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 14 (66.67) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Asís, SE; Buldain, GY; Frank, FM; Muscia, GC; Roldán Pacheco, FJ | 1 |
| Garcia, AA; Koperniku, A; Mochly-Rosen, D | 1 |
| Arana-Argaez, VE; Bottazzi, ME; Cruz-Chan, JV; Dumonteil, E; Dzul-Huchim, VM; Gusovsky, F; Hotez, P; Martinez-Vega, PP; Ortega-Lopez, J; Ramirez-Sierra, MJ; Rosado-Vallado, ME; Villanueva-Lizama, LE | 1 |
| Caldas, IS; Chagas-Paula, DA; Diniz, LF; Fernandes, VHC; Gonçalves-Santos, E; Mazzeti, AL; Novaes, RD; Oliveira, CM; Rodrigues, MR; Veloso, MP; Vilas-Boas, DF | 1 |
| Cevey, ÁC; Donato, M; Gelpi, RJ; Goren, NB; Mirkin, GA; Penas, FN; Rada, MJ | 1 |
| Arrúa, EC; Esteva, MI; Fichera, LE; Rial, MS; Salomon, CJ; Scalise, ML | 1 |
| Camargo, RS; Carneiro, ZA; de Albuquerque, S; do Vale, GT; Portapilla, GB; Providello, MV; Tirapelli, CR | 1 |
| Chin, CM; da Rosa, JA; de Andrade, CR; Dos Santos, JL; Scarim, CB | 1 |
| Gonçalves, RV; Maldonado, IRSC; Mendonça, AAS; Natali, AJ; Novaes, RD; Souza-Silva, TG; Talvani, A | 1 |
| Carneiro, ZA; da Silva, RS; Milanezi, C; Santos, M; Sesti-Costa, R; Silva, GK; Silva, JS; Silva, MC | 1 |
| Araújo, MS; Carneiro, CM; Lana, Md; Machado-de-Assis, GF; Martins, HR; Martins-Filho, OA; Oliveira, MT; Oliveira-Silva, JC; Paiva, NC | 1 |
| Bastos, DS; Cardoso, SA; Gonçalves, WG; Novaes, RD; Oliveira, JM; Oliveira, LL; Penitente, AR; Santos, EC; Talvani, A | 1 |
| de Paula Costa, G; Horta, AL; Leite, AL; Natali, AJ; Neves, CA; Penitente, AR; Shrestha, D; Talvani, A | 1 |
| Cevey, ÁC; Goren, NB; Mirkin, GA; Penas, FN | 1 |
| Carnovale, CE; Catania, VA; de Luján Alvarez, M; Francés, DE; Lambertucci, F; Martín-Sanz, P; Motiño, O; Quiroga, AD; Rigalli, JP; Ronco, MT; Villar, S | 1 |
| Bottasso, E; Bottasso, O; Manarin, R; Revelli, S; Serra, E | 1 |
| Cruz-Zetina, G; del Rio-Rodriguez, R; López, R; Monteon, V; Ramos-Ligonio, A | 1 |
| Bozza, MT; Freire-De-Lima, CG; Gibaldi, D; Heise, N; Mendonça-Previato, L; Previato, JO; Saraiva, VB | 1 |
| Alves, CF; Bahia, MT; Carneiro, CM; Cruz, RE; Lana, M; Machado-Coelho, GL; Martins, HR; Tafuri, WL; Toledo, MJ; Veloso, VM | 1 |
| Amigorena, S; Bottasso, O; Guermonprez, P; Nocito, AL; Pascutti, MF; Pitashny, M; Revelli, S; Serra, E; Wietzerbin, J | 1 |
1 review(s) available for benzonidazole and Inflammation
| Article | Year |
|---|---|
Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
Topics: Communicable Diseases; Drug Discovery; Glucosephosphate Dehydrogenase; High-Throughput Screening Assays; Humans; Inflammation; Neoplasms | 2022 |
20 other study(ies) available for benzonidazole and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Hit-to-lead optimization of novel 2-alkylaminomethylquinoline derivatives as anti-chagas agents.
Topics: Animals; Cell Survival; Chagas Disease; Chlorocebus aethiops; Dose-Response Relationship, Drug; Female; Inflammation; Mice; Mice, Inbred C3H; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2020 |
Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice.
Topics: Adjuvants, Immunologic; Animals; Chagas Disease; Dogs; Fibrosis; Humans; Inflammation; Mice; Mice, Inbred BALB C; Nitroimidazoles; Perforin; Protozoan Vaccines; Recombinant Proteins; Toll-Like Receptor 4; Trypanosoma cruzi; Vaccines, Combined; Vaccines, DNA | 2022 |
Sesquiterpene lactone potentiates the immunomodulatory, antiparasitic and cardioprotective effects on anti-Trypanosoma cruzi specific chemotherapy.
Topics: Animals; Antiparasitic Agents; Cardiotonic Agents; Cell Line; Chagas Disease; Cytokines; Female; Immunologic Factors; Inflammation; Lactones; Mice; Myocarditis; Nitroimidazoles; Parasitemia; Rats; Sesquiterpenes; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2019 |
Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Diastole; Fenofibrate; Fibrosis; Humans; Inflammation; Interleukin-6; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Nitroimidazoles; PPAR alpha; Stroke Volume; Trypanocidal Agents; Trypanosoma cruzi; Tumor Necrosis Factor-alpha; Ventricular Dysfunction; Ventricular Function | 2017 |
Elucidating the impact of low doses of nano-formulated benznidazole in acute experimental Chagas disease.
Topics: Animals; Antibodies, Protozoan; Cell Line; Chagas Disease; Chlorocebus aethiops; Disease Models, Animal; DNA, Protozoan; Drug Carriers; Female; Heart; Inflammation; Mice; Mice, Inbred C3H; Nanoparticles; Nitroimidazoles; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2017 |
Benefits of Ascorbic Acid in Association with Low-Dose Benznidazole in Treatment of Chagas Disease.
Topics: Animals; Antioxidants; Ascorbic Acid; Chagas Disease; Drug Therapy, Combination; Inflammation; Lipid Peroxidation; Male; Mice; Nitroimidazoles; Oxidation-Reduction; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi | 2018 |
Hydroxymethylnitrofurazone treatment in indeterminate form of chronic Chagas disease: Reduced intensity of tissue parasitism and inflammation-A histopathological study.
Topics: Animals; Chagas Disease; Disease Models, Animal; Inflammation; Kidney; Liver; Male; Mice; Muscle, Skeletal; Nitrofurazone; Nitroimidazoles; Trypanosoma cruzi | 2018 |
Concomitant exercise training attenuates the cardioprotective effects of pharmacological therapy in a murine model of acute infectious myocarditis.
Topics: Animals; Antioxidants; Cardiotonic Agents; Catalase; Chagas Cardiomyopathy; Chagas Disease; Cytokines; Disease Models, Animal; Heart; Inflammation; Interleukin-10; Male; Myocarditis; Myocardium; Nitric Oxide; Nitroimidazoles; Parasitemia; Physical Conditioning, Animal; Rats; Rats, Wistar; Superoxide Dismutase; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2019 |
Ruthenium complex with benznidazole and nitric oxide as a new candidate for the treatment of chagas disease.
Topics: Animals; Chagas Disease; Drug Resistance; Drug Therapy, Combination; Female; Heart; Humans; Inflammation; Mice; Nitric Oxide; Nitroimidazoles; Parasitemia; Ruthenium; Trypanocidal Agents; Trypanosoma cruzi | 2014 |
Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease.
Topics: Animals; Antibodies, Protozoan; Area Under Curve; Brazil; Chagas Disease; Child; Disease Models, Animal; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis; Flow Cytometry; Humans; Inflammation; Mice; Myocardium; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Primary Cell Culture; Remission Induction; Statistics, Nonparametric; Trypanocidal Agents; Trypanosoma cruzi | 2015 |
Modulation of oxidative and inflammatory cardiac response by nonselective 1- and 2-cyclooxygenase inhibitor and benznidazole in mice.
Topics: Administration, Oral; Animals; Antioxidants; Catalase; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glutathione Peroxidase; Ibuprofen; Immunosuppressive Agents; Inflammation; Male; Mice; Nitroimidazoles; Oxidative Stress; Random Allocation; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase | 2015 |
Enalapril in Combination with Benznidazole Reduces Cardiac Inflammation and Creatine Kinases in Mice Chronically Infected with Trypanosoma cruzi.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Chagas Cardiomyopathy; Enalapril; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi | 2015 |
Low-dose benznidazole treatment results in parasite clearance and attenuates heart inflammatory reaction in an experimental model of infection with a highly virulent Trypanosoma cruzi strain.
Topics: Animals; Cells, Cultured; Chagas Cardiomyopathy; Chagas Disease; Creatine Kinase; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Humans; Immunologic Factors; Inflammation; Interleukin-6; Mice; Mice, Inbred BALB C; Myocytes, Cardiac; NF-kappa B; Nitric Oxide Synthase Type II; Nitroimidazoles; Parasite Load; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2016 |
Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.
Topics: Animals; Antioxidants; Chagas Disease; Disease Models, Animal; Down-Regulation; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitroimidazoles; Oxidative Stress; Sepsis; Toll-Like Receptor 4; Trypanocidal Agents | 2017 |
Beneficial effects of benznidazole during an infectious-based situation of systemic inflammatory response: cecal ligation and puncture.
Topics: Animals; Bacteremia; Chagas Disease; Enzyme-Linked Immunosorbent Assay; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitroimidazoles; Trypanocidal Agents; Tumor Necrosis Factor-alpha | 2008 |
Decreased intensity of inflammation in benznidazole-treated mice inoculated with Trypanosoma cruzi I stocks from Mexico and persistence of circulating parasites.
Topics: Animals; Cardiomyopathies; Chagas Disease; Genotype; Heart; Inflammation; Mexico; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi | 2012 |
Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Drug Resistance; Exudates and Transudates; Inflammation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitroimidazoles; omega-N-Methylarginine; Phosphorylcholine; Survival Analysis; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2002 |
Effects of specific treatment on parasitological and histopathological parameters in mice infected with different Trypanosoma cruzi clonal genotypes.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Cloning, Molecular; Female; Genotype; Heart; Inflammation; Itraconazole; Mice; Mice, Inbred BALB C; Myocardium; Nitroimidazoles; Trypanosoma cruzi; Urogenital System | 2004 |
Benznidazole, a drug used in Chagas' disease, ameliorates LPS-induced inflammatory response in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chagas Disease; DNA Primers; Dose-Response Relationship, Drug; Endotoxemia; Flow Cytometry; Inflammation; Interleukin-10; Interleukin-12; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroimidazoles; Peritoneal Lavage; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Trypanocidal Agents; Tumor Necrosis Factor-alpha | 2004 |