Page last updated: 2024-08-23

benzonidazole and Experimental Neoplasms

benzonidazole has been researched along with Experimental Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, JM; Hazlehurst, JL; Hirst, DG1
Owen, LN; Twentyman, PR; Walton, MI; White, RA; Workman, P1
Bleehen, NM; Walton, MI; Workman, P1
Walton, MI; Workman, P1

Other Studies

4 other study(ies) available for benzonidazole and Experimental Neoplasms

ArticleYear
Sensitization of normal and malignant tissue to cyclophosphamide by nitroimidazoles with different partition coefficients.
    British journal of cancer, 1984, Volume: 49, Issue:1

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Etanidazole; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Preclinical pharmacokinetics of benznidazole.
    British journal of cancer, 1984, Volume: 50, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain; Chromatography, High Pressure Liquid; Dogs; Drug Evaluation, Preclinical; Female; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Pharmaceutical Vehicles; Sheep

1984
Stimulation by localized tumor hyperthermia of reductive bioactivation of 2-nitroimidazole benznidazole in mice.
    Cancer research, 1989, May-01, Volume: 49, Issue:9

    Topics: Amines; Animals; Hyperthermia, Induced; Liver; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Oxidation-Reduction

1989
Nitroimidazole bioreductive metabolism. Quantitation and characterisation of mouse tissue benznidazole nitroreductases in vivo and in vitro.
    Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytosol; Kidney; Kinetics; Liver; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Neoplasms, Experimental; Nitroimidazoles; Nitroreductases; Oxidoreductases

1987