Page last updated: 2024-08-23

benzonidazole and Disease Exacerbation

benzonidazole has been researched along with Disease Exacerbation in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (22.73)29.6817
2010's14 (63.64)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Bottazzi, ME; Dean, DA; Hossain, E; Hotez, PJ; Jones, KM; Kane, SS; Kendricks, AL; Leão, AC; Liu, Z; McCall, LI; Pollet, J; Sankaranarayanan, K; Ulrich vonBargen, R; Wheeler, K1
Díaz, ML; Echeverría, LE; Eduardo Nieto, J; González, CI; Hernandez, JCM; López-Romero, LA; Morillo, CA; Ochoa, SAG; Rivera, JD; Rojas, LZ; Suárez, EU1
Alonso-Padilla, J; Alonso-Vega, C; Cortés-Serra, N; Gascón, J; Losada Galván, I; Pinazo, MJ1
Bahia, MT; Caldas, IS; Caldas, S; Diniz, LF; Menezes, APJ; Nascimento, ÁFDSD; Novaes, RD1
Egui, A; Lasso, P; López, MC; Pérez-Antón, E; Thomas, MC1
Echeverria, LE; Morillo, CA1
Asti, L; Bartsch, SM; Bottazzi, ME; Falcón-Lezama, JA; Hotez, PJ; Lee, BY; Meymandi, S; Randall, S; Strych, U1
Coura, JR; de Macedo, RC; Ferreira, AG; Junqueira, AC; Pinto, AY; Santos, LC; Valente, SA; Valente, Vda C1
Albajar-Viñas, P; Coura, JR; Dias, JC; Diniz, GA; Lana, Md; Machado-Coelho, GL; Machado-de-Assis, GF; Montoya, RA; Torres, RM1
Avezum, A; Bonilla, L; Bonilla, R; Britto, C; Connolly, SJ; Guhl, F; Lazdins, J; Marin-Neto, JA; Mattos, A; Meeks, B; Morillo, CA; Pogue, J; Quiroz, R; Rao-Melacini, P; Rassi, A; Rosas, F; Sosa-Estani, S; Velazquez, E; Villena, E; Yusuf, S1
Ciapponi, A; Comandé, D; Cuesta, CB; Hicks, E; Roberts, KN; Sguassero, Y; Sosa-Estani, S1
Bierrenbach, AL; Cardoso, CS; Cunha-Neto, E; de Oliveira, LC; Ferreira, AM; Ferreira, JE; Haikal, DS; Oliveira, CD; Reingold, AL; Ribeiro, AL; Sabino, EC1
Pays, JF1
Marin, JA; Rassi, A1
Condon, D; Dhiman, M; Garg, NJ; Guan, Z; Gupta, S; Lui, C; Wen, JJ1
Bern, C1
Ayala, E; Fisa, R; Gállego, M; Gascon, J; Monteagudo, J; Muñoz, J; Pinazo, MJ; Posada, Ede J; Reverter, JC; Tàssies, D1
Colmenarez-Mendoza, HJ; Dávila-Spinetti, DF; Lobo-Vielma, L1
Alvarez, MG; Armenti, A; Bertocchi, G; Lococo, B; Petti, M; Vigliano, C; Viotti, R1
Alvarez, MG; Armenti, A; Bertocchi, G; Lococo, B; Petti, M; Postan, M; Vigliano, C; Viotti, R1
Del Bigio, MR; Nijjar, SS1

Reviews

4 review(s) available for benzonidazole and Disease Exacerbation

ArticleYear
Dynamics of T Cells Repertoire During Trypanosoma cruzi Infection and its Post-Treatment Modulation.
    Current medicinal chemistry, 2019, Volume: 26, Issue:36

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chagas Disease; Chronic Disease; Disease Progression; Humans; Infectious Disease Transmission, Vertical; Nitroimidazoles; Risk Factors; Trypanosoma cruzi

2019
American Trypanosomiasis (Chagas Disease).
    Infectious disease clinics of North America, 2019, Volume: 33, Issue:1

    Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Clinical Trials as Topic; Disease Progression; Disease Vectors; Humans; Nitroimidazoles; Triatominae; Trypanocidal Agents; Trypanosoma cruzi

2019
Course of Chronic Trypanosoma cruzi Infection after Treatment Based on Parasitological and Serological Tests: A Systematic Review of Follow-Up Studies.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Adult; Antibodies, Protozoan; Chagas Disease; Child; Chronic Disease; Cohort Studies; Disease Progression; DNA, Protozoan; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Follow-Up Studies; Hemagglutination Tests; Humans; Nifurtimox; Nitroimidazoles; Parasitemia; Randomized Controlled Trials as Topic; Treatment Failure; Trypanocidal Agents; Trypanosoma cruzi; Xenodiagnosis

2015
Antitrypanosomal therapy for chronic Chagas' disease.
    The New England journal of medicine, 2011, Jun-30, Volume: 364, Issue:26

    Topics: Adult; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Electrocardiography; Female; Humans; Life Cycle Stages; Nifurtimox; Nitroimidazoles; Practice Guidelines as Topic; Trypanocidal Agents; Trypanosoma cruzi

2011

Trials

2 trial(s) available for benzonidazole and Disease Exacerbation

ArticleYear
Randomized Trial of Benznidazole for Chronic Chagas' Cardiomyopathy.
    The New England journal of medicine, 2015, Volume: 373, Issue:14

    Topics: Adult; Aged; Cardiovascular Diseases; Chagas Cardiomyopathy; Chronic Disease; Disease Progression; Female; Genotype; Humans; Male; Middle Aged; Nitroimidazoles; Parasite Load; Polymerase Chain Reaction; Proportional Hazards Models; Prospective Studies; Treatment Failure; Trypanocidal Agents; Trypanosoma cruzi

2015
Long-term cardiac outcomes of treating chronic Chagas disease with benznidazole versus no treatment: a nonrandomized trial.
    Annals of internal medicine, 2006, May-16, Volume: 144, Issue:10

    Topics: Adult; Animals; Antibodies, Protozoan; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prognosis; Sensitivity and Specificity; Trypanocidal Agents; Trypanosoma cruzi

2006

Other Studies

16 other study(ies) available for benzonidazole and Disease Exacerbation

ArticleYear
Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease.
    Nature communications, 2023, 10-25, Volume: 14, Issue:1

    Topics: Animals; Chagas Disease; Disease Progression; Heart; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2023
Efficacy of the Benznidazole+Posaconazole combination therapy in parasitemia reduction: An experimental murine model of acute Chagas.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Acute Disease; Animals; Chagas Disease; Disease Models, Animal; Disease Progression; DNA, Protozoan; Drug Therapy, Combination; Nitroimidazoles; Parasite Load; Parasitemia; Rats; Rats, Wistar; Triazoles; Trypanocidal Agents

2020
Benznidazole for the treatment of Chagas disease.
    Expert review of anti-infective therapy, 2021, Volume: 19, Issue:5

    Topics: Adult; Chagas Disease; Disease Progression; Female; Humans; Infectious Disease Transmission, Vertical; Nitroimidazoles; Pregnancy; Pregnancy Complications, Infectious; Trypanocidal Agents

2021
Parasitaemia and parasitic load are limited targets of the aetiological treatment to control the progression of cardiac fibrosis and chronic cardiomyopathy in Trypanosoma cruzi-infected dogs.
    Acta tropica, 2019, Volume: 189

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Chronic Disease; Collagen Type III; Disease Models, Animal; Disease Progression; DNA, Protozoan; Dogs; Drug Resistance; Fibrosis; Heart; Myocardium; Nitroimidazoles; Parasite Load; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi

2019
Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients.
    Vaccine, 2019, 06-19, Volume: 37, Issue:28

    Topics: Cardiomyopathies; Chagas Disease; Chronic Disease; Cost-Benefit Analysis; Disease Progression; Humans; Nitroimidazoles; Trypanosoma cruzi; Vaccination; Vaccines

2019
Clinical follow-up of responses to treatment with benznidazol in Amazon: a cohort study of acute Chagas disease.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibodies, Protozoan; Brazil; Chagas Cardiomyopathy; Chagas Disease; Child; Child, Preschool; Disease Progression; Follow-Up Studies; Humans; Immunoglobulin G; Middle Aged; Nitroimidazoles; Topography, Medical; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2013
A serological, parasitological and clinical evaluation of untreated Chagas disease patients and those treated with benznidazole before and thirteen years after intervention.
    Memorias do Instituto Oswaldo Cruz, 2013, Volume: 108, Issue:7

    Topics: Adolescent; Adult; Case-Control Studies; Chagas Disease; Child; Disease Progression; Female; Humans; Male; Nitroimidazoles; Polymerase Chain Reaction; Prognosis; Retrospective Studies; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2013
Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile.
    BMJ open, 2016, 05-04, Volume: 6, Issue:5

    Topics: Aged; Biomarkers; Brazil; Chagas Cardiomyopathy; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Heart Failure; Humans; Immunosuppressive Agents; Longitudinal Studies; Male; Middle Aged; Natriuretic Peptide, Brain; Nitroimidazoles; Peptide Fragments; Population Surveillance; Predictive Value of Tests; Prognosis; Prospective Studies; Quality of Life; Socioeconomic Factors

2016
[The third and new face of Chagas disease].
    Bulletin de la Societe de pathologie exotique (1990), 2016, Volume: 109, Issue:3

    Topics: Adult; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Humans; Neglected Diseases; Nitroimidazoles; Treatment Failure

2016
Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial.
    Memorias do Instituto Oswaldo Cruz, 2017, Volume: 112, Issue:3

    Topics: Animals; Chagas Cardiomyopathy; Chronic Disease; Clinical Trials as Topic; Disease Progression; Female; Humans; Latin America; Male; Middle Aged; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2017
Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats.
    Journal of the American College of Cardiology, 2010, Jun-01, Volume: 55, Issue:22

    Topics: Analysis of Variance; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Disease Progression; Heart Function Tests; Hemodynamics; Lipid Peroxidation; Mitochondria, Heart; Nitroimidazoles; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Trypanosoma cruzi

2010
Hypercoagulability biomarkers in Trypanosoma cruzi -infected patients.
    Thrombosis and haemostasis, 2011, Volume: 106, Issue:4

    Topics: Adult; Biomarkers; Biomarkers, Pharmacological; Chagas Disease; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prothrombin; Risk; Thrombin; Thromboembolism; Thrombophilia; Trypanosoma cruzi

2011
[Mechanisms responsible for myocardial damage progression in chronic Chagas' disease].
    Revista espanola de cardiologia, 2005, Volume: 58, Issue:9

    Topics: Allopurinol; Antimetabolites; Chagas Cardiomyopathy; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Electrocardiography; Follow-Up Studies; Humans; Nitroimidazoles; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Trypanocidal Agents

2005
[Clinical predictors of chronic chagasic myocarditis progression].
    Revista espanola de cardiologia, 2005, Volume: 58, Issue:9

    Topics: Adult; Chagas Cardiomyopathy; Disease Progression; Echocardiography; Electrocardiography; Follow-Up Studies; Heart Failure; Humans; Middle Aged; Myocarditis; Nitroimidazoles; Prognosis; Proportional Hazards Models; Risk Factors; Time Factors; Trypanocidal Agents

2005
Summaries for patients. Long-term outcomes of treating nonacute Chagas disease with benznidazole.
    Annals of internal medicine, 2006, May-16, Volume: 144, Issue:10

    Topics: Adult; Animals; Antibodies, Protozoan; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Progression; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prognosis; Sensitivity and Specificity; Trypanocidal Agents; Trypanosoma cruzi

2006
Cerebral trypanosomiasis in an incarcerated man.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007, Feb-13, Volume: 176, Issue:4

    Topics: Adult; Animals; Biopsy, Needle; Central Nervous System Protozoal Infections; Craniotomy; Disease Progression; Fatal Outcome; Humans; Immunohistochemistry; Male; Manitoba; Nitroimidazoles; Prisoners; Tomography, X-Ray Computed; Trypanosoma; Trypanosomiasis

2007