Page last updated: 2024-08-23

benzonidazole and Chemical and Drug Induced Liver Injury

benzonidazole has been researched along with Chemical and Drug Induced Liver Injury in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Beccacece, A; Carrara, S; Comandini, UV; Corpolongo, A; Del Nonno, F; Giancola, ML; Maffongelli, G; Mariano, A; Montalbano, M; Nicastri, E; Petrone, A1
Rendon, DA1
Basombrio, MA; Davies, C; Dey, N; Garg, NJ; Negrette, OS; Parada, LA1

Other Studies

4 other study(ies) available for benzonidazole and Chemical and Drug Induced Liver Injury

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Severe drug-induced liver injury (DILI) associated with benznidazole therapy for Chagas' disease.
    The Journal of antimicrobial chemotherapy, 2022, 11-28, Volume: 77, Issue:12

    Topics: Chagas Cardiomyopathy; Chagas Disease; Chemical and Drug Induced Liver Injury; Humans; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2022
Alterations of mitochondria in liver but not in heart homogenates after treatment of rats with benznidazole.
    Human & experimental toxicology, 2014, Volume: 33, Issue:10

    Topics: Adenosine Diphosphate; Animals; Cell Respiration; Chemical and Drug Induced Liver Injury; Female; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membranes; Mitochondrial Proton-Translocating ATPases; Nitroimidazoles; Oxidative Phosphorylation; Rats, Wistar

2014
Hepatotoxicity in mice of a novel anti-parasite drug candidate hydroxymethylnitrofurazone: a comparison with Benznidazole.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:10

    Topics: Animals; Cell Death; Cell Line, Tumor; Chagas Disease; Chemical and Drug Induced Liver Injury; DNA Damage; Female; Hep G2 Cells; Humans; Liver; Male; Mice; Mitochondria; Nifurtimox; Nitrofurazone; Nitroimidazoles; Parasites; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi; Tumor Necrosis Factor-alpha; Tyrosine

2014