benzonidazole has been researched along with Adverse Drug Event in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 9 (60.00) | 24.3611 |
| 2020's | 5 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| de Lima, ME; Freire-de-Lima, L; Heise, N; Mendonça-Previato, L; Previato, JO; Ribeiro, TS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Breynaert, A; De Bruyne, T; Hermans, N; Huits, R; Truyens, C; Van Den Broucke, S; Van Esbroeck, M; Van Herreweghe, M | 1 |
| Carrilero, B; Franco, F; García-Vázquez, E; Gil-Gallardo, LJ; Iborra, MA; Segovia, M; Simón, M; Vázquez, C | 1 |
| Arsuaga, M; Crespillo-Andújar, C; Díaz-Menéndez, M; López-Vélez, R; Monge-Maillo, B; Norman, F; Pérez-Molina, JA; Trigo, E | 1 |
| Arruda, HMBDS; Gontijo, MKCL; Noronha, EF; Toledo, MI | 1 |
| Almeida, IC; Alonso-Vega, C; Barboza, T; Barreira, F; Bilbe, G; Blum, B; Correia, E; Garcia, W; Gascón, J; Ortiz, L; Parrado, R; Ramirez, JC; Ribeiro, I; Sosa-Estani, S; Strub-Wourgaft, N; Torrico, F; Vaillant, M | 1 |
| Aldasoro, E; Calvo-Cano, A; Casellas, A; Gascon, J; Pinazo, MJ; Posada, E; Requena-Méndez, A; Sanz, S; Serret, N; Soy, D | 1 |
| Almeida, IC; Alonso-Vega, C; Alves, F; Gascon, J; Ortiz, L; Pinazo, MJ; Ribeiro, I; Schijman, A; Strub-Wourgaft, N; Torrico, F | 1 |
| Chamorro-Tojeiro, S; Crespillo-Andújar, C; López-Vélez, R; Monge-Maillo, B; Norman, F; Pérez-Molina, JA | 1 |
| Bern, C; Castellon, M; Gilman, RH; Lozano Beltran, DF; Solano Mercado, MA; Sullca, W; Tornheim, JA; Torrico, F | 1 |
| Alvarenga Americano do Brasil, PE; da Costa Chambela, M; da Silva, JA; de Sousa, AS; Hasslocher-Moreno, AM; Magalhães Saraiva, R; Mediano, MF; Rodrigues da Costa, A; Sperandio da Silva, GM; Xavier, SS | 1 |
| Eells, SJ; Hernandez, S; Meymandi, SK; Miller, DA; Miller, LG; Rodriguez De Armas, L; Traina, MM | 1 |
| Bocanegra, C; Molina, I; Pou, D; Roure, S; Salvador, F; Sánchez-Montalvá, A; Serre, N; Sulleiro, E; Treviño, B; Valerio, L | 1 |
| Chambela, MC; de Sousa, AS; do Brasil, PE; Hasslocher-Moreno, AM; Sperandio da Silva, GM; Xavier, SS | 1 |
4 trial(s) available for benzonidazole and Adverse Drug Event
| Article | Year |
|---|---|
New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial.
Topics: Adult; Bolivia; Chagas Disease; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Nitroimidazoles; Parasite Load; Treatment Outcome; Triazoles; Young Adult | 2021 |
What to expect and when: benznidazole toxicity in chronic Chagas' disease treatment.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Chagas Disease; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Trypanocidal Agents; Young Adult | 2018 |
Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Bolivia; Chagas Disease; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Male; Middle Aged; Nitroimidazoles; Parasite Load; Placebos; Polymerase Chain Reaction; Prospective Studies; Thiazoles; Treatment Outcome; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Young Adult | 2018 |
Improved completion rates and characterization of drug reactions with an intensive Chagas disease treatment program in rural Bolivia.
Topics: Adolescent; Adult; Antiprotozoal Agents; Bolivia; Chagas Disease; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Medication Adherence; Middle Aged; Nitroimidazoles; Prospective Studies; Rural Population; Treatment Outcome; Young Adult | 2013 |
11 other study(ies) available for benzonidazole and Adverse Drug Event
| Article | Year |
|---|---|
Toxic effects of natural piperine and its derivatives on epimastigotes and amastigotes of Trypanosoma cruzi.
Topics: Alkaloids; Animals; Benzodioxoles; Cells, Cultured; Chagas Disease; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Humans; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Piperidines; Polyunsaturated Alkamides; Trypanocidal Agents; Trypanosoma cruzi | 2004 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Mitigation of benznidazole toxicity and oxidative stress following ascorbic acid supplementation in an adult traveller with chronic indeterminate Chagas' disease.
Topics: Adult; Antioxidants; Ascorbic Acid; Biomarkers; Chagas Disease; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Humans; Nitroimidazoles; Oxidative Stress | 2022 |
Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole.
Topics: Chagas Disease; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Humans; Nitroimidazoles; Prospective Studies; Retrospective Studies; Trypanocidal Agents; Trypanosoma cruzi | 2023 |
Comparison of the toxicity of two treatment schemes with benznidazole for chronic Chagas disease: a prospective cohort study in two Spanish referral centres.
Topics: Adult; Chagas Disease; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Nitroimidazoles; Prospective Studies; Referral and Consultation; Spain; Trypanocidal Agents; Trypanosoma cruzi | 2020 |
Characterization of adverse reactions to benznidazole in patients with Chagas disease in the Federal District, Brazil.
Topics: Adult; Brazil; Chagas Disease; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Female; Fluorescent Antibody Technique, Indirect; Hemagglutination Tests; Hospitals, Public; Humans; Incidence; Male; Middle Aged; Nitroimidazoles; Severity of Illness Index; Socioeconomic Factors; Trypanocidal Agents | 2020 |
Toxicity of nifurtimox as second-line treatment after benznidazole intolerance in patients with chronic Chagas disease: when available options fail.
Topics: Adult; Chagas Disease; Chronic Disease; Cohort Studies; Drug Tolerance; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Prospective Studies; Retreatment; Trypanosoma cruzi | 2018 |
A clinical adverse drug reaction prediction model for patients with chagas disease treated with benznidazole.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Biomarkers; Chagas Disease; Drug-Related Side Effects and Adverse Reactions; Educational Status; Female; Humans; Logistic Models; Male; Nitroimidazoles; Racial Groups; Sex Factors; Trypanocidal Agents; Trypanosoma cruzi; Young Adult | 2014 |
Tolerance of benznidazole in a United States Chagas Disease clinic.
Topics: Adolescent; Adult; Aged; Angioedema; Chagas Disease; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Nitroimidazoles; Peripheral Nervous System Diseases; Retrospective Studies; Trypanocidal Agents; United States; Young Adult | 2015 |
Immunosuppression and Chagas disease; experience from a non-endemic country.
Topics: Adolescent; Adult; Aged; Antiprotozoal Agents; Chagas Disease; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunocompromised Host; Infant; Male; Middle Aged; Nitroimidazoles; Retrospective Studies; Spain; Treatment Outcome; Trypanosoma cruzi; Young Adult | 2015 |
Safety of benznidazole use in the treatment of chronic Chagas' disease.
Topics: Adolescent; Adult; Aged; Algorithms; Antiprotozoal Agents; Chagas Disease; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Models, Statistical; Nitroimidazoles; Young Adult | 2012 |